LMPD Database

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LMP013058

UniProt Annotations

Entry Information
Gene Nameinositol-3-phosphate synthase 1
Protein EntryINO1_RAT
UniProt IDQ6AYK3
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityD-glucose 6-phosphate = 1D-myo-inositol 3- phosphate.
CofactorName=NAD(+); Xref=ChEBI:CHEBI:57540; Evidence= ;
FunctionKey enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity)
PathwayPolyol metabolism; myo-inositol biosynthesis; myo- inositol from D-glucose 6-phosphate: step 1/2.
SimilarityBelongs to the myo-inositol 1-phosphate synthase family
Subcellular LocationCytoplasm .