LMPD Database

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LMP013066

UniProt Annotations

Entry Information
Gene Nameglycosylphosphatidylinositol specific phospholipase D1
Protein EntryPHLD_RAT
UniProt IDQ8R2H5
SpeciesRat
Comments
Comment typeDescription
Catalytic Activity6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D- myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1D-myo-inositol + phosphatidate.
FunctionThis protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane.
PtmGlycosylated
SimilarityBelongs to the GPLD1 family
SimilarityContains 7 FG-GAP repeats
Subcellular LocationSecreted. Note=Associated with the High- Density Lipoproteins (HDL)
SubunitMonomer