LMPD Database

LMP013367

Gene Information

Entrez Gene ID	313929
Gene Name	nuclear receptor coactivator 1
Gene Symbol	Ncoa1
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:RGD	C	cytoplasm
GO:0043005	IDA:RGD	C	neuron projection
GO:0000790	IEA:Ensembl	C	nuclear chromatin
GO:0005634	IDA:RGD	C	nucleus
GO:0003682	IEA:Ensembl	F	chromatin binding
GO:0030331	IPI:RGD	F	estrogen receptor binding
GO:0004402	IEA:InterPro	F	histone acetyltransferase activity
GO:0016922	IPI:RGD	F	ligand-dependent nuclear receptor binding
GO:0030374	IEA:Ensembl	F	ligand-dependent nuclear receptor transcription coactivator activity
GO:0033142	IPI:RGD	F	progesterone receptor binding
GO:0032403	IPI:RGD	F	protein complex binding
GO:0042974	IPI:RGD	F	retinoic acid receptor binding
GO:0046965	IPI:RGD	F	retinoid X receptor binding
GO:0001012	IDA:RGD	F	RNA polymerase II regulatory region DNA binding
GO:0004871	IEA:InterPro	F	signal transducer activity
GO:0008134	IPI:RGD	F	transcription factor binding
GO:0032870	IMP:RGD	P	cellular response to hormone stimulus
GO:0021549	IEP:RGD	P	cerebellum development
GO:0021987	IEP:RGD	P	cerebral cortex development
GO:0021766	IEP:RGD	P	hippocampus development
GO:0043967	IEA:Ensembl	P	histone H4 acetylation
GO:0021854	IEP:RGD	P	hypothalamus development
GO:0060713	IEA:Ensembl	P	labyrinthine layer morphogenesis
GO:0007595	IEP:RGD	P	lactation
GO:0008584	IEP:RGD	P	male gonad development
GO:0060179	IMP:RGD	P	male mating behavior
GO:0042698	IEP:RGD	P	ovulation cycle
GO:0043065	IEA:Ensembl	P	positive regulation of apoptotic process
GO:0045925	IMP:RGD	P	positive regulation of female receptivity
GO:0045666	IEA:Ensembl	P	positive regulation of neuron differentiation
GO:0045944	IMP:RGD	P	positive regulation of transcription from RNA polymerase II promoter
GO:0000435	IEA:Ensembl	P	positive regulation of transcription from RNA polymerase II promoter by galactose
GO:2001038	IEA:Ensembl	P	regulation of cellular response to drug
GO:0032355	IMP:RGD	P	response to estradiol
GO:0009725	IEP:RGD	P	response to hormone
GO:0032570	IMP:RGD	P	response to progesterone
GO:0032526	IMP:RGD	P	response to retinoic acid
GO:0006351	IEA:UniProtKB-KW	P	transcription, DNA-templated

KEGG Pathway Links

KEGG Pathway ID	Description
rno04919	Thyroid hormone signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
5954496	Activation of gene expression by SREBF (SREBP)
5953720	Bile acid and bile salt metabolism
5953258	Biological oxidations
5954332	BMAL1:CLOCK,NPAS2 activates circadian gene expression
5954223	Circadian Clock
5953485	Cytochrome P450 - arranged by substrate type
5953533	Developmental Biology
5953932	Endogenous sterols
5953288	Fatty acid, triacylglycerol, and ketone body metabolism
5953330	Gene Expression
5953833	Generic Transcription Pathway
5953250	Metabolism
5953289	Metabolism of lipids and lipoproteins
5953600	Mitochondrial biogenesis
5953601	Organelle biogenesis and maintenance
5953326	Phase 1 - Functionalization of compounds
5954333	PPARA activates gene expression
5953719	Recycling of bile acids and salts
5954497	Regulation of cholesterol biosynthesis by SREBP (SREBF)
5954222	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
5954224	REV-ERBA represses gene expression
5954225	RORA activates circadian gene expression
5953930	Synthesis of bile acids and bile salts
5953929	Synthesis of bile acids and bile salts via 27-hydroxycholesterol
5953931	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
5953599	Transcriptional activation of mitochondrial biogenesis
5954166	Transcriptional regulation of white adipocyte differentiation
5954528	YAP1- and WWTR1 (TAZ)-stimulated gene expression