LMPD Database

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LMP013440

UniProt Annotations

Entry Information
Gene Nameethylmalonyl-CoA decarboxylase 1
Protein EntryECHD1_RAT
UniProt IDQ6AYG5
SpeciesRat
Comments
Comment typeDescription
Catalytic Activity(S)-ethylmalonyl-CoA = butanoyl-CoA + CO(2).
Catalytic Activity(S)-methylmalonyl-CoA = propanoyl-CoA + CO(2).
FunctionDecarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level (By similarity)
SimilarityBelongs to the enoyl-CoA hydratase/isomerase family
Subcellular LocationCytoplasm, cytosol .