LMPD Database

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LMP013474

UniProt Annotations

Entry Information
Gene Namelysophosphatidylcholine acyltransferase 3
Protein EntryMBOA5_RAT
UniProt IDQ5FVN0
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine.
DomainThe di-lysine motif confers endoplasmic reticulum localization
FunctionSeems to be the major enzyme contributing to lysophosphatidylcholine acyltransferase activity in the liver. Favors unsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Displays lysophosphatidylserine acyltransferase (LPSAT) activity (By similarity)
PathwayLipid metabolism; phospholipid metabolism.
SimilarityBelongs to the membrane-bound acyltransferase family
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .