LMPD Database

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LMP013492

UniProt Annotations

Entry Information
Gene Namecholine phosphotransferase 1
Protein EntryCHPT1_RAT
UniProt IDQ66H21
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityCDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence= ; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence= ;
FunctionCatalyzes phosphatidylcholine biosynthesis from CDP- choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity)
PathwayPhospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 2/2.
SimilarityBelongs to the CDP-alcohol phosphatidyltransferase class-I family
Subcellular LocationGolgi apparatus membrane ; Multi-pass membrane protein .