LMPD Database

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LMP013565

UniProt Annotations

Entry Information
Gene Namechemokine (C-X-C motif) ligand 16
Protein EntryCXL16_RAT
UniProt IDQ6AXU5
SpeciesRat
Comments
Comment typeDescription
FunctionInduces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity)
InductionBy interleukin-18 and the induction is strongly mediated by an activator protein-1-dependent pathway
PtmGlycosylated
SimilarityBelongs to the intercrine alpha (chemokine CxC) family
Subcellular LocationMembrane ; Single-pass type I membrane protein .