LMPD Database

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LMP013646

UniProt Annotations

Entry Information
Gene Namealcohol dehydrogenase 5 (class III), chi polypeptide
Protein EntryADHX_RAT
UniProt IDP12711
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityAn alcohol + NAD(+) = an aldehyde or ketone + NADH.
Catalytic ActivityS-(hydroxymethyl)glutathione + NAD(P)(+) = S- formylglutathione + NAD(P)H.
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence= ; Note=Binds 2 Zn(2+) ions per subunit. ;
FunctionClass-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
Sequence CautionSequence=AAH83724.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily
Subcellular LocationCytoplasm.
SubunitHomodimer.