LMPD Database

LMP014071

Gene Information

Entrez Gene ID	613025
Gene Name	estrogen receptor 1
Gene Symbol	ESR1
Species	Macaca mulatta

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IEA:Ensembl	C	cytoplasm
GO:0005634	IEA:UniProtKB-SubCell	C	nucleus
GO:0005886	IEA:Ensembl	C	plasma membrane
GO:0003682	IEA:Ensembl	F	chromatin binding
GO:0001046	IEA:Ensembl	F	core promoter sequence-specific DNA binding
GO:0038052	IEA:Ensembl	F	estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0034056	IEA:Ensembl	F	estrogen response element binding
GO:0000978	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0005496	IEA:UniProtKB-KW	F	steroid binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0008209	IEA:Ensembl	P	androgen metabolic process
GO:0001547	IEA:Ensembl	P	antral ovarian follicle growth
GO:0071391	IEA:Ensembl	P	cellular response to estrogen stimulus
GO:0002064	IEA:Ensembl	P	epithelial cell development
GO:0060750	IEA:Ensembl	P	epithelial cell proliferation involved in mammary gland duct elongation
GO:0008584	IEA:Ensembl	P	male gonad development
GO:0060749	IEA:Ensembl	P	mammary gland alveolus development
GO:0060745	IEA:Ensembl	P	mammary gland branching involved in pregnancy
GO:0010629	IEA:Ensembl	P	negative regulation of gene expression
GO:0043124	IEA:Ensembl	P	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043433	IEA:Ensembl	P	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0048146	IEA:Ensembl	P	positive regulation of fibroblast proliferation
GO:0045429	IEA:Ensembl	P	positive regulation of nitric oxide biosynthetic process
GO:0051000	IEA:Ensembl	P	positive regulation of nitric-oxide synthase activity
GO:0048386	IEA:Ensembl	P	positive regulation of retinoic acid receptor signaling pathway
GO:0051091	IEA:Ensembl	P	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060527	IEA:Ensembl	P	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060523	IEA:Ensembl	P	prostate epithelial cord elongation
GO:0042981	IEA:Ensembl	P	regulation of apoptotic process
GO:0060687	IEA:Ensembl	P	regulation of branching involved in prostate gland morphogenesis
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0060065	IEA:Ensembl	P	uterus development
GO:0060068	IEA:Ensembl	P	vagina development

KEGG Pathway Links

KEGG Pathway ID	Description
ko04961	Endocrine and other factor-regulated calcium reabsorption
mcc04961	Endocrine and other factor-regulated calcium reabsorption
ko04915	Estrogen signaling pathway
mcc04915	Estrogen signaling pathway
ko04917	Prolactin signaling pathway
mcc04917	Prolactin signaling pathway
ko05205	Proteoglycans in cancer
mcc05205	Proteoglycans in cancer
mcc04919	Thyroid hormone signaling pathway