Lipidomics studies on macrophages - RAW 264.7 cells treated with Kdo2-Lipid A and compactin

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Legend:graph_icon: View data/graphs for replicates    graph icon: View graphs of average of replicates
PA| PC| PE| PG| PI| PS| DNA| TNF

Details/Graph
LM_ID NameMass
(neutral)		 Kdo+Comp
Kdo
Comp
Ctrl
 0 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 0.5 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 1 hr		 Kdo+Comp
Kdo
Comp
Ctrl
 2 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 4 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 8 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 12 hrs		 Kdo+Comp
Kdo
Comp
Ctrl
 24 hrs
Units
. . . .
  - PC(28:0)677.5 (ions) -
-
-
3.6		 2.92
2.19
3.33
4.17		 3.29
2.56
2.03
2.08		 3.33
3.25
2.8
3.75		 2.72
2.68
1.95
2.41		 2.43
3.78
1.87
1.86		 3.7
4.2
1.63
1.49		 5.29
5.22
2.05
2.08		 pmol/ug DNA
  - PC(32:0)733.6 (ions) -
-
-
19.1		 15.2
14.2
14.6
16.8		 13.9
14.8
11.7
13.3		 14.4
14
13.4
15.5		 15.3
16.5
14.3
13.9		 21
23.3
12.6
13.1		 25
26.1
12.1
12.3		 27.5
27.5
10.8
13.2		 pmol/ug DNA
  - PC(32:1)731.5 (ions) -
-
-
80		 79.1
73
73.8
78.7		 69.4
72.4
65.1
72.7		 78.8
73
69.1
80.1		 60.1
69.9
65.9
74.1		 67.5
83.6
57.5
60.9		 76.7
83.5
50.9
49.6		 74
78.9
41.8
45.3		 pmol/ug DNA
  - PC(32:2)729.5 (ions) -
-
-
15.8		 15.4
13.3
15
16.1		 13
13.4
12.3
13.7		 15.6
14.8
13.9
15.8		 11.9
13.9
13.3
14.6		 11.1
14.7
10.9
12.5		 10.7
12.6
8.87
8.98		 9.43
10.4
7.39
8.25		 pmol/ug DNA
  - PC(34:1)759.6 (ions) -
-
-
52.3		 48.5
45.3
45.3
47.2		 42.4
45.5
39.8
45.2		 48.5
42.6
41.5
45.7		 36.4
41.3
39.6
42		 41.6
48.5
36.7
34		 49.2
50.8
31.9
30.4		 46.8
49.6
26.7
29.3		 pmol/ug DNA
  - PC(34:2)757.6 (ions) -
-
-
32.9		 32.2
30.6
30.1
31.8		 28.1
30.2
27.4
30.3		 32.8
30.2
28.5
32.7		 24.4
27.5
27.6
30.1		 22.6
28.9
23.7
25.4		 23.1
26.6
19.7
20		 18.9
22.5
14.6
17.9		 pmol/ug DNA
  - PC(34:3)755.5 (ions) -
-
-
2.45		 2.6
1.98
3.3
4.02		 3.58
2.46
2.84
2.95		 4.08
4.33
2.81
3.18		 2.5
2.83
2.9
2.86		 2.5
2.9
2.28
2.79		 2.26
3.98
1.9
1.74		 3.22
3.46
2.04
2.58		 pmol/ug DNA
  - PC(36:0)789.6 (ions) -
-
-
4.77		 6.63
3.43
4.02
2.67		 4.52
3.26
2.6
4.9		 5.64
2.19
4.55
6.29		 3.63
3.79
2.64
2.1		 1.3
1.28
1.76
3.99		 2.62
1.87
2.27
2.93		 6.92
6.98
3.57
1.64		 pmol/ug DNA
  - PC(36:1)787.6 (ions) -
-
-
52.1		 39.4
38.5
40.3
42.6		 34.1
37.7
32.5
36.5		 31
32.9
33.7
37.3		 25.9
33.9
34.4
30.1		 34.8
42.3
25.5
26		 55.8
55
29
26.8		 70.2
73.4
36.9
35.7		 pmol/ug DNA
  - PC(36:2)785.6 (ions) -
-
-
85.4		 99.1
94.2
95.5
99.4		 84.6
94.8
85.7
93.4		 90.6
87.4
87.6
96.3		 69.3
85.1
84.9
86.9		 68.8
85.3
70.9
73.8		 74.1
83.6
64.6
61.6		 63.9
75.4
57.3
67.8		 pmol/ug DNA
  - PC(36:2e)/PC(36:1p)771.6 (ions) -
-
-
11.2		 9.85
8.14
8.43
9.33		 9.12
8.55
7.22
7.79		 7.68
8.66
7.4
8.98		 5.99
6.97
6.3
7.63		 5.95
7.9
5.74
6.34		 7.77
9.14
5.87
5.31		 8.2
9.41
6.94
7.81		 pmol/ug DNA
  - PC(36:3)783.6 (ions) -
-
-
24.5		 22.1
21.1
22.7
20.4		 21.3
19.9
18.4
20.2		 22.5
20.1
20.8
21.5		 17.3
19.8
18.4
19.6		 15.5
20.5
14.7
16.8		 17.2
17.3
11.6
12.5		 12.2
15.1
8.06
10.7		 pmol/ug DNA
  - PC(36:3e)/PC(36:2p)769.6 (ions) -
-
-
4.14		 3.91
3.6
4.59
3.47		 4.12
3.55
3.85
3.14		 4.08
3.96
3.67
3.85		 1.78
2.49
2.36
2.78		 2.41
4.41
1.99
1.79		 3.36
4.23
1.41
1.81		 4.01
3.93
2.51
2.95		 pmol/ug DNA
  - PC(36:4)781.6 (ions) -
-
-
14.5		 14
11.6
11.9
12.9		 14.6
14.5
8.78
10.3		 13.1
12.5
10.4
12.3		 11.1
12.2
9.33
9.27		 8.1
12.2
6.8
7.01		 10.6
10.9
4.45
3.3		 8.4
9.78
4.92
5.6		 pmol/ug DNA
  - PC(36:4e)/PC(36:3p)767.6 (ions) -
-
-
1.86		 3.84
1.69
1.83
3.97		 4.26
2.94
3.19
3.06		 5.39
3.94
4.04
6.18		 2.89
2.99
2.9
3.75		 2.21
3.93
3.74
2.54		 3.22
4.12
1.03
1.78		 4.04
4.93
0.95
1.99		 pmol/ug DNA
  - PC(36:5e)/PC(36:4p)765.6 (ions) -
-
-
15.6		 12.9
8.63
12.4
14.4		 8.35
9.34
8.7
11.6		 8.42
11.7
9.31
12.5		 7.6
9.36
7.89
12.3		 10.4
11.6
6.22
11.7		 11.6
21.6
10.6
10.5		 21.9
23.6
9.27
13		 pmol/ug DNA
  - PC(38:0)817.7 (ions) -
-
-
50.3		 46.7
29.7
29.5
42.5		 38.6
39.1
20.5
35.4		 35
36.8
44.2
46.3		 49.6
45
52.2
32.1		 34.9
35.9
28.8
37.2		 38.2
28.3
27.3
32.9		 23.4
31.3
20.6
16.3		 pmol/ug DNA
  - PC(38:1)815.6 (ions) -
-
-
-		 18.1
2.89
23.8
37.9		 6.18
4.66
2.01
11.7		 17.6
9.23
4.47
-		 7.76
6.59
9.04
14.9		 5.67
2.26
3.06
4.79		 2.77
10.8
2.95
3.21		 17.7
28.1
13.6
7.29		 pmol/ug DNA
  - PC(38:2)813.6 (ions) -
-
-
27.4		 15.2
10.5
14.4
11.2		 12.9
9.96
8.94
10.2		 10.5
11.3
9.73
10.8		 6.13
6.99
9.5
9.11		 6.44
12.9
6.75
6.31		 13
16.6
8.03
7.74		 12.9
15.2
11
10.6		 pmol/ug DNA
  - PC(38:3)811.6 (ions) -
-
-
16.5		 13.9
12.4
15.9
13.6		 12.3
12.9
11
12.3		 13.5
12.1
13.2
13.1		 7.23
10.3
11.2
10.4		 8.94
11.9
7.17
7.2		 12.5
12.4
7.76
7.37		 12.4
11.6
10.7
11.2		 pmol/ug DNA
  - PC(38:4)809.6 (ions) -
-
-
24.1		 24.7
20.5
21.5
25.4		 22.9
23.1
17.3
22.4		 19.7
21.6
19.1
20.7		 15.1
18.5
17.8
15.9		 11.4
17.9
10
11.8		 15.4
15.5
9.99
8.67		 13.5
15.6
10.2
11.3		 pmol/ug DNA
  - PC(38:5e)/PC(38:4p)793.6 (ions) -
-
-
9.05		 4.39
4.57
5.57
7.1		 5.33
5.74
4.46
5.2		 4.63
7.15
5.41
3.79		 3.63
3.76
3.25
3.46		 2.36
3.76
2.33
4.21		 5.06
7.42
2.4
2.76		 2.98
4.98
2.21
2.65		 pmol/ug DNA
  - PC(38:6)805.6 (ions) -
-
-
31.6		 23.1
22.4
26.3
26.9		 22.8
24
21.4
21.8		 19.7
20.8
21.9
24.2		 15.9
20.9
20.6
19		 18.6
21.6
16
16.1		 23.7
23
16.7
15.6		 26.6
28.5
18.3
20.9		 pmol/ug DNA
  - PC(38:6e)/PC(38:5p)791.6 (ions) -
-
-
-		 -
-
-
-		 4.94
0.1
0.8
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 -
-
-
-		 pmol/ug DNA
  - PC(40:1)843.7 (ions) -
-
-
-		 17.7
8.9
19.9
23.7		 13.5
12.8
6.93
13.9		 10
11.8
12.2
15		 13.3
13.9
16.3
7.04		 9.63
10.4
6.67
8.46		 12
8.87
5.67
7.72		 11.9
10.7
8.52
3.35		 pmol/ug DNA
  - PC(40:2)841.7 (ions) -
-
-
-		 10.4
5.58
26.6
36		 9.42
9.7
4.71
8.82		 12
7.96
8.16
10.4		 12.2
10.2
9.73
9.64		 6.23
7.71
3.81
5.43		 7.55
7.7
3.08
3.98		 22.5
8.74
7.62
3.6		 pmol/ug DNA
  - PC(40:3)839.6 (ions) -
-
-
6.31		 10.6
7.83
8.47
6.63		 10.1
8.65
6.32
8.96		 9.37
8.2
12.3
14.3		 6.38
6.9
4.7
10.1		 4.31
10.3
8.16
7.43		 5.69
3.18
6.36
5.35		 5.37
4.53
5.87
3.42		 pmol/ug DNA
  - PC(40:4)837.6 (ions) -
-
-
7.8		 7.52
6.06
8.31
7.57		 11.2
13.1
10
10.4		 10.6
12
9.44
10.3		 8.58
8.17
8.21
11.1		 5.82
13.5
4.85
8.47		 8.53
9.16
4.61
5.16		 6.74
9.89
6.45
4.55		 pmol/ug DNA
  - PC(40:5)835.6 (ions) -
-
-
13.8		 10.9
10.1
10.6
11.6		 12.4
15.3
11.4
10.8		 10.7
13.5
9.45
13.9		 11.1
10
11.7
9.76		 5.11
10.1
4.31
3.47		 9.68
5.94
6.48
6.26		 10.3
8.71
6.94
4.86		 pmol/ug DNA
  - PC(40:6)833.6 (ions) -
-
-
20.6		 22.7
16.4
24.7
25.1		 24.2
22.7
16
19.8		 24.1
19.1
18.1
20.1		 14.5
18.4
12.4
19.5		 11.1
16.5
12.5
13.2		 17.7
20.4
11.7
13		 27.3
26.2
21.1
15.8		 pmol/ug DNA