Lipidomics studies on macrophages - RAW 264.7 cells treated with Kdo2-Lipid A and compactin

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Legend:graph_icon: View data/graphs for replicates    graph icon: View graphs of average of replicates
PA| PC| PE| PG| PI| PS| DNA| TNF

Details/Graph
LM_ID NameMass
(neutral)
Kdo+Comp
Kdo
Comp
Ctrl
0 hrs
Kdo+Comp
Kdo
Comp
Ctrl
0.5 hrs
Kdo+Comp
Kdo
Comp
Ctrl
1 hr
Kdo+Comp
Kdo
Comp
Ctrl
2 hrs
Kdo+Comp
Kdo
Comp
Ctrl
4 hrs
Kdo+Comp
Kdo
Comp
Ctrl
8 hrs
Kdo+Comp
Kdo
Comp
Ctrl
12 hrs
Kdo+Comp
Kdo
Comp
Ctrl
24 hrs

Units
. . . .
  - PE(32:0)691.5 (ions) -
-
-
3.68
2.5
1.33
3.44
2.6
1.37
1.3
1.02
1.52
2.1
1.51
1.57
1.07
2.18
1.27
1.4
1.43
1.28
1.38
1.7
1.32
2.06
2.19
1.64
0.963
3.32
2.02
1.86
0.945
pmol/ug DNA
  - PE(32:1)689.5 (ions) -
-
-
9.47
7.08
6.47
7.41
7.44
6.52
6.88
5.76
6.38
7.04
7.04
6.19
6.68
8.64
6.84
6.96
6.7
5.73
6.89
6.35
6.79
6.87
8.06
5.32
5.12
7.82
7.19
4.78
3.79
pmol/ug DNA
  - PE(34:0)719.5 (ions) -
-
-
5.67
3.67
2.95
5
3.96
2.23
2.83
2.14
2.66
2.71
2.52
2.53
2.69
3.67
2.63
2.54
2.23
2.12
2.13
2.41
2.33
3.47
3.46
2.57
1.77
4.97
3.28
2.89
1.52
pmol/ug DNA
  - PE(34:1)717.5 (ions) -
-
-
23.4
19.8
20.5
19
19.2
18.5
20.4
18.1
18.6
19
19.3
18.3
18.1
24.6
20
19.4
20.2
17.2
21.1
18.2
19.1
19.6
22.6
15.8
14.9
20.3
19.9
13.5
11.4
pmol/ug DNA
  - PE(34:2)715.5 (ions) -
-
-
14.4
11.7
11.6
12.5
12.2
10.7
12.1
10.3
11.1
11.5
12.2
11.2
11.1
13
11.3
13
13.6
8.39
10.5
10.6
11.4
9.44
11.2
8.63
8.15
10.8
10.5
7.32
7.24
pmol/ug DNA
  - PE(36:0)747.6 (ions) -
-
-
15.2
12.6
14.4
12
10.6
11.9
11.7
11.2
12.2
9.49
8.64
10.5
10.8
9.18
9.4
8.16
9.8
8.73
9.55
7.24
6.58
8.81
11.9
6.11
7.09
11.4
11
7.04
4.41
pmol/ug DNA
  - PE(36:1)745.6 (ions) -
-
-
35.1
29.7
33.9
31
30.4
28.4
31.5
28.6
29.5
29.5
27.8
27.1
27.3
36.9
29.3
28
29.5
25.3
28.8
22.9
27.3
30.8
30.8
22.6
20.8
30
31.8
22.4
17.1
pmol/ug DNA
  - PE(36:1e)/PE(36:0p)731.6 (ions) -
-
-
6.67
5.15
4.76
6.81
5.53
3.6
4.48
3.18
4.57
4.78
4.48
4.04
3.9
5.53
3.31
4.09
3.93
3.37
4.41
3.79
3.58
4.47
5.47
3.74
3.21
7.11
5.71
4.21
2.6
pmol/ug DNA
  - PE(36:2)743.5 (ions) -
-
-
42
36.1
39.5
36.7
36
33.6
38.5
34.9
36.5
35.1
34.4
33.6
33.5
39.1
33.8
33.5
36.2
24.3
29.9
30.5
32.2
24.6
30.1
26
23.9
24.4
26.7
24.3
21.8
pmol/ug DNA
  - PE(36:2e)/PE(36:1p)729.6 (ions) -
-
-
14.8
11.2
13.3
12.4
11.8
11.7
12.6
12.1
10.3
11.4
9.42
11.4
11.2
11
9.69
9.82
11.9
9.09
12
11
10.2
11.4
13.9
10.2
9.79
15.3
16.6
10.1
8.52
pmol/ug DNA
  - PE(36:3)741.5 (ions) -
-
-
14.8
11.1
10.8
12.8
11.8
9.04
10.2
9.25
10.6
10.9
9.97
9.3
9.61
11.6
9.82
8.84
10.4
7.1
8.66
8.85
9.48
8.69
10
7.68
6.58
11.9
9.84
7.82
6.53
pmol/ug DNA
  - PE(36:3e)/PE(36:2p)727.6 (ions) -
-
-
11.6
9.04
11.1
11.6
9.92
9.48
11.4
9.7
9.5
9.32
7.99
8.77
9.65
8.44
8.57
8.14
10.1
8.1
9.74
8.76
8.28
8.16
9.69
7.32
8.37
9.75
10.2
8.08
7.69
pmol/ug DNA
  - PE(36:4)739.5 (ions) -
-
-
20.3
13.3
14
16.1
15.3
12.7
12.8
11.3
11.5
13.4
12.3
11.6
12.9
16.5
10.6
10.7
10.6
9.08
10.5
9.36
10.4
10.6
13.9
8.67
7.59
15.5
12.2
7.53
5.9
pmol/ug DNA
  - PE(36:4e)/PE(36:3p)725.5 (ions) -
-
-
9.9
9.82
14
10.1
10.9
10.6
11.3
10.8
10.5
9.94
9.08
9.81
11.1
8.7
9.58
8.88
10.8
9.27
11.3
9.15
8.93
9.85
12.5
7.65
9.28
13.6
13.4
8.02
8.09
pmol/ug DNA
  - PE(36:5)737.5 (ions) -
-
-
9.89
6.53
5.28
9.14
6.74
3.84
4.45
5.24
5.13
5.38
4.18
4.36
4.11
7.29
3.61
5.42
7.27
3.38
4.19
4.27
2.81
4.64
6.96
4.02
2.74
7.79
5.84
5.44
2.19
pmol/ug DNA
  - PE(36:5e)/PE(36:4p)723.5 (ions) -
-
-
20.4
19.1
13.9
20.9
15.8
20
20.8
19.8
19.4
19
16.2
16.3
18.3
13.2
14.4
12.1
17.8
14.2
16.7
12.9
11.8
13.4
17.3
9.54
12
18.6
17.9
8.79
7.43
pmol/ug DNA
  - PE(38:0)775.6 (ions) -
-
-
18.5
11.6
13
15.1
13.3
10.3
15
13.4
9.7
10.5
8.18
8.61
10.2
6.77
6.35
7.43
8.51
7.07
8.01
7.49
5.74
9.75
10.1
6.53
5.94
13.5
10.1
7.54
4.83
pmol/ug DNA
  - PE(38:1)773.6 (ions) -
-
-
8.6
7.9
11.9
7.45
8.12
8.29
8.59
8.41
8.25
7.14
6.34
6.89
7.37
6.33
6.2
5.94
6.27
5.61
6.03
4.52
5.31
5.33
5.38
3.97
4.85
5.36
5.35
3.68
3.12
pmol/ug DNA
  - PE(38:2)771.6 (ions) -
-
-
8.86
7.7
7.57
9.9
7.6
5.41
6.47
5.76
5.65
4.35
5.18
6.41
6.13
4.42
5.78
4.46
5.41
4.2
4.64
4.21
3.91
3.99
5.81
4.26
4.53
8.57
6.34
6.14
3.81
pmol/ug DNA
  - PE(38:3)769.6 (ions) -
-
-
29
19.7
24.8
21.7
25.1
20.9
21.3
20.3
21.3
19.4
20.6
18.7
20.2
33.5
19.6
20.3
15.6
13.7
16.3
11.8
18.1
16.5
15.1
11.3
14.3
13.9
16.6
14.5
11.7
pmol/ug DNA
  - PE(38:3e)/PE(38:2p)755.6 (ions) -
-
-
13.2
12.3
14.1
11.9
12.2
11
12.9
11.6
12.3
10.8
11.2
10.8
11.1
11.3
10.8
10.8
10.5
9.13
10.2
9.18
9.65
10.1
10.1
8.78
8.87
11.4
11.6
9.96
9
pmol/ug DNA
  - PE(38:4)767.5 (ions) -
-
-
53.7
43.3
51.5
45
44.1
41.5
46.8
41.3
44.4
37.3
38.7
38.1
38.3
56.6
38.6
40.4
38.2
27.9
32.3
30.2
32.4
32.4
31
28
24.3
32.8
33.6
21.1
18
pmol/ug DNA
  - PE(38:5)765.5 (ions) -
-
-
27.7
23.6
25.9
25.4
24.4
22.6
23.8
21.9
23.5
19.7
21.2
20.5
20.8
22.8
20
18.9
19.7
14.2
17.5
14.5
15.8
13.9
17.6
13
12.5
16.8
15.1
11
9.77
pmol/ug DNA
  - PE(38:5e)/PE(38:4p)751.6 (ions) -
-
-
27.7
25.7
32.9
26.5
25.9
27.1
29.3
28.9
29
25
22
23.9
26.1
22.2
21.6
18.7
25.2
21.4
24.3
18.2
17.9
20.8
24.8
15.4
17.8
25.9
25.2
15.5
13.4
pmol/ug DNA
  - PE(38:6)763.5 (ions) -
-
-
11.6
8.49
7.81
9.58
9.26
6.56
6.87
5.82
7.46
7.61
6.82
6.54
6.62
8.32
5.35
5.85
6.13
4.33
4.75
5.06
5.13
5.52
6.74
4.71
3.23
8.5
5.91
4.62
2.59
pmol/ug DNA
  - PE(38:6e)/PE(38:5p)749.5 (ions) -
-
-
31.5
19.7
27.1
20.5
23.3
23.2
23.9
23.2
23
20.5
17.6
20
21.6
14.9
16.8
14.7
19.9
16.2
17.9
14
13.5
14.6
17.9
11
13.1
18.3
16.1
9.5
9.01
pmol/ug DNA
  - PE(40:2)799.6 (ions) -
-
-
4.99
3.36
2.44
4.97
3.68
1.56
1.61
1.37
2.05
2.73
2.17
1.91
1.62
1.22
1.23
1.45
1.62
0.908
1.21
1.7
1.56
2.04
2.56
1.69
1.07
4.54
2.97
2.88
1.24
pmol/ug DNA
  - PE(40:3)797.6 (ions) -
-
-
7.87
4.48
4.11
7.25
6.14
2.79
4.01
3.2
3.53
4
3.6
2.92
3.54
2.44
2.97
3.61
3.29
2.4
2.82
2.86
2.51
3.36
4.09
2.51
1.97
6.4
4.83
4.17
2.1
pmol/ug DNA
  - PE(40:4)795.6 (ions) -
-
-
7.94
10.3
11.6
6.34
6.49
8.28
9.24
8.47
8.48
7.49
8.51
7.47
8.41
60.1
12
15.4
6.72
8.18
6.4
6.56
10.7
8.83
6.74
6.66
6.23
8.04
7.16
5.16
3.81
pmol/ug DNA
  - PE(40:5)793.6 (ions) -
-
-
15.2
11.9
12.6
13
13
10.6
10.9
10.1
11.2
8.21
9.14
9.69
9.19
19.1
10.1
11.2
8.06
7.11
7.64
7.73
8.19
8.86
9.31
6.88
6.06
11.2
9
5.12
3.98
pmol/ug DNA
  - PE(40:6)791.5 (ions) -
-
-
18.8
12
16.1
16.1
15.7
12.6
14
12.2
12.6
12.3
11.2
10.9
11.7
19.8
11.8
13.6
10.6
8.27
9.47
9.61
9.63
10.3
10.3
8.35
6.52
11.2
9.19
5.97
3.69
pmol/ug DNA
  - PE(40:7)789.5 (ions) -
-
-
11.2
7.84
7
8.68
8.15
5.12
5.49
4.89
6.32
6.46
6.31
5.29
5.07
6.66
4.23
5.23
5.28
2.87
3.29
3.87
3.71
2.9
5.93
3.29
2.71
6.14
4.49
3.64
2.1
pmol/ug DNA