LIPID MAPS® Gene/Proteome Database (LMPD)

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LMP011438

Record overview

LMPD IDLMP011438
Gene ID824702
SpeciesArabidopsis thaliana (Arabidopsis)
Gene Namevery-long-chain enoyl-CoA reductase
Gene SymbolCER10
SynonymsATTSC13; CER10; ECERIFERUM 10; ECR; ENOYL-COA REDUCTASE; TSC13
Alternate namesvery-long-chain enoyl-CoA reductase
Chromosome3
EC Number1.3.1.93
SummaryEnoyl-CoA reductase is involved in all very long chain fatty acids (VLCFA) elongation reactions that are required for cuticular wax, storage lipid and sphingolipid metabolism. The protein is located in the ER, but in contrast to its yeast homolog TSC13 is not particularly enriched in the nuclear envelope-vacuole junction. Mutants in this gene show abnormal organ morphology and stem glossiness. Cells in all tissues are only about 1/3 of the size of wild type cells. The morphological changes are most likely to result from the reduction in the VLCFA content of sphingolipids. Mutants also show abnormalities in the endocytic membrane organization and transport.
OrthologsView orthologs and multiple alignments for CER10

Proteins

very-long-chain enoyl-CoA reductase
Refseq ID:NP_191096
Protein GI:15233250
UniProt ID:Q9M2U2
mRNA ID:NM_115394
Length:310
RefSeq Status:REVIEWED
MKVTVVSRSGREVLKAPLDLPDSATVADLQEAFHKRAKKFYPSRQRLTLPVTPGSKDKPVVLNSKKSLKEYCDGNNNSLTVVFKDLGAQVSYRTLFFFEY
LGPLLIYPVFYYFPVYKFLGYGEDCVIHPVQTYAMYYWCFHYFKRILETFFVHRFSHATSPIGNVFRNCAYYWSFGAYIAYYVNHPLYTPVSDLQMKIGF
GFGLVCQVANFYCHILLKNLRDPSGAGGYQIPRGFLFNIVTCANYTTEIYQWLGFNIATQTIAGYVFLAVAALIMTNWALGKHSRLRKIFDGKDGKPKYP
RRWVILPPFL