Highlights from the Lipid Analysis Literature - latest Month

The following references were collected in a weekly literature search that reflects my (former) personal research interests, although most mainstream lipid analytical topics are covered. Among the exceptions are "steroidal hormones", "prostanoids", "fat-soluble vitamins" and "terpenoids", although some papers in these categories may be posted. My intention is to list only those papers that exhibit novel analytical methodology as opposed to tried and tested methods, although this may appear to introduce a bias towards modern mass spectrometry techniques, and the titles of more than 1500 references are scanned each month to make the selection. Some papers in press may be listed here without the full citation, but the DOI address should still be valid, and they may be updated later. References are listed alphabetically by the first author.

References Collected in October, 2024

Aladag, S. and others. A facile and efficient protocol for phospholipid enrichment in synovial joint fluid: monodisperse-mesoporous SiO2 microspheres as a new metal oxide affinity sorbent. Separations, 11, 262 (2024); DOI.
Arias-Santé, M.F., López-Puebla, S., de Camargo, A.C., Guil-Guerrero, J.L. and Rincón-Cervera, M.A. Development and validation of a simple analytical method to quantify tocopherol isoforms in food matrices by HPLC-UV-Vis. Appl. Sci. Basel, 14, 8750 (2024); DOI.
Arteaga-Clemente, G., García-González, M.A. and González-González, M. Soil lipid analysis by chromatography: A critical review of the current state in sample preparation. J. Chromatogr. Open, 6, 100173 (2024); DOI.
Burla, B. and others. Plasma and platelet lipidome changes in Fabry disease. Clin. Chim. Acta, 562, 119833 (2024); DOI.
Carpanedo, L., Rund, K.M., Wende, L.M., Kampschulte, N. and Schebb, N.H. LC-HRMS analysis of phospholipids bearing oxylipins. Anal. Chim. Acta, 1326, 343139 (2024); DOI.
Castro, K.D., Tose, L.V., Willetts, M., Park, M.A., Nouzova, M., Norieg, F.G. and Fernandez-Lima, F. Tracing de novo lipids using stable isotope labeling LCTIMS-TOF MS/MS. JOVE-J. Vis. Exp., e65590 (2024); DOI.
Cavo, I., Fresnedo, O., Mosteiro, L., López, J.I., Larrinaga, G. and Fernández, J.A. Lipid imaging mass spectrometry: Towards a new molecular histology. Biochim. Biophys. Acta, Lipids, 1870, 159568 (2025); DOI.
Chen, F., Peng, D.B., Xia, Y.Y., Sun, H.X., Shen, H. and Xia, M. Identification of oxylipins and lipid mediators in pulmonary embolism. Lipids Health Dis., 23, 330 (2024); DOI.
Chen, X. and others. Polymeric phenylpropanoid derivatives crosslinked by hydroxyl fatty acids form the core structure of rape sporopollenin. Nature Plants, in press (2024); DOI.
Fatima, Z., Chugh, M., Nigam, G. and Hameed, S. Quantification of mycolic acids in different mycobacterial species by standard addition method through liquid chromatography mass spectrometry. J. Chromatogr. B, 1247, 124297 (2024); DOI.
He, F.F., Liu, G., Huang, D.Y., Wang, Z., Zhao, A.Z. and Wang, X.Y. Liquid chromatography-mass spectrometry analysis of major lipid species in Bacteroides thetaiotaomicron VPI 5482. Systems Microbiol. Bioman., in press (2024); DOI.
Hernández-Cravero, B., Prez, G., Lombardo, V.A., Guastaferri, F.V., Delprato, C.B., Altabe, S., de Mendoza, D. and Binolfi, A. A high-resolution 13C NMR approach for profiling fatty acid unsaturation in lipid extracts and in live Caenorhabditis elegans. J. Lipid Res., 65, 100618 (2024); DOI.
Ingham, B., Hollywood, K., Wongsirichot, P., Veitch, A. and Winterburn, J. Uncovering the fragmentation and separation characteristics of sophorolipid biosurfactants with LC-MS-ESI. J. Indust. Microbiol. Biotechn., 51, kuae035 (2024); DOI.
Janker, T., Brun, A., Sievers-Engler, A., Dittrich, K., Gawaz, M. and Lämmerhofer, M. Targeted ultra-high performance liquid chromatography-tandem mass spectrometry assay for the quantification of medium-chain phosphatidylcholines in platelets of coronary artery disease patients. J. Chromatogr. Open, 6, 100160 (2024); DOI.
Jekimovs, L.J., Akefe, I.O., Wallis, T.P., Young, R.S.E., Brydon, S.C., Meunier, F.A., Poad, B.L.J. and Blanksby, S.J. Making OzID go FFASTer: Combining stable-isotope tagging with ozone-induced dissociation to uncover changes in fatty acid unsaturation within neurosecretory cells. Int. J. Mass Spectrom., 506, 117342 (2024); DOI.
Kchaou, M., Soltani, S., Frikha, D., Maalej, S., Allouche, N. and Ben Salah, H. New acid anhydride from Phalaris canariensis with antimicrobial activity assessed through in vitro and in silico approaches. Nat. Prod. Res., in press (2024); DOI.
Kumar, R., Breukink, E. and Weingarth, M. Isolation and molecular characterization of the LTA precursor molecule Glc2-DAG, a potential target for antibiotics. Chembiochem, in press (2024); DOI.
Linares-Maurizi, A. and others. Stress-induced production of bioactive oxylipins in marine microalgae. Marine Drugs, 22, 406 (2024); DOI.
Liu, R. and others. Corynebacterium parakroppenstedtii secretes a novel glycolipid to promote the development of granulomatous lobular mastitis. Signal Transd. Targeted Ther., 9, 292 (2024); DOI.
Ma, Y.J., Li, P., Zhu, B.W., Du, M. and Xu, X.B. Comprehensive determination of fatty acids in real samples without derivatization by DMU-SPME-GC methods. Food Res. Int., 195, 114986 (2024); DOI.
McAtamney, A., Ferranti, A., Ludvik, D.A., Yildiz, F.H., Mandel, M.J., Hayward, T. and Sanchez, L.M. Microbial metabolomics' latest SICRIT: soft ionization by chemical reaction in-transfer mass spectrometry. J. Am. Soc. Mass Spectrom., in press (2024); DOI.
Montone, C.M., Cavaliere, C., Cerrato, A., Laganà, A., Piovesana, S., Taglioni, E. and Capriotti, A.L. Detailed lipid investigation of edible seaweeds by photochemical derivatization and untargeted lipidomics. Anal. Bioanal. Chem., in press (2024); DOI.
Olfert, M., Knappe, C., Sievers-Engler, A., Masberg, B. and Lämmerhofer, M. Determination of double bond positions in unsaturated fatty acids by pre-column derivatization with dimethyl and dipyridyl disulfide followed by LC-SWATH-MS analysis. Anal. Bioanal. Chem., in press (2024); DOI.
Prieto, H.D., Cole, .LM., Forbes, S., Palmer, M. and Schwartz-Narbonne, R. Separation of mycolic acid isomers by cyclic ion mobility-mass spectrometry. Rapid Commun. Mass Spectrom., 38, e9917 (2024); DOI.
Qin, Y., Zhuang, H.D., Zhang, Y. and Chen, Y. Analysis of lipid composition of cell-bound membrane vesicles (CBMVs) derived from endothelial cells. Biochem. Biophys. Res. Commun., 733, 150722 (2024); DOI.
Roberts, J.A., Radnoff, A.S., Bushueva, A., Menard, J.A., Wasslen, K.V., Harley, M., Manthorpe, J.M. and Smith, J.C. Mobile phase contaminants affect neutral lipid analysis in LC-MS-based lipidomics studies. J. Am. Soc. Mass Spectrom., in press (2024); DOI.
Sanni, A. and others. An optimized liquid chromatography-mass spectrometry method for ganglioside analysis in cell lines. Cells, 13, 1640 (2024); DOI.
Slijkhuis, N., Towers, M., Claude, E. and van Soest, G. MALDI versus DESI mass spectrometry imaging of lipids in atherosclerotic plaque. Rapid Commun. Mass Spectrom., 39, e9927 (2025); DOI.
Sobhi, H.F. and others. Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues. J. Lipid Res., 65, 100632 (2024); DOI.
Striesow, J., Nasri, Z., von Woedtke, T., Bekeschus, S. and Wende, K. Epilipidomics reveals lipid fatty acid and headgroup modification in gas plasma-oxidized biomembranes. Redox Biol., 77, 103343 (2024); DOI.
Takeda, H., Takeuchi, M., Hasegawa, M., Miyamoto, J. and Tsugawa, H. A procedure for solid-phase extractions using metal-oxide-coated silica column in lipidomics. Anal. Chem., 96, 17065-17070 (2024); DOI.
Tang, S., Wang, H., Zhang, H.H., Zhang, M.Y., Xu, J.C., Yang, C., Chen, X.S. and Guo, X.H. Simultaneous determination of the position and cis-trans configuration of lipid C=C bonds via asymmetric derivatization and ion mobility-mass spectrometry. J. Am. Chem. Soc., 146, 29503-29512 (2024); DOI.
Torta, F. and others. Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards. Nature Commun., 15, 8562 (2024); DOI.
Vandergrift, G.W., Kew, W., Andersen, A., Lukowski, J.K., Goo, Y.A. and Anderton, C.R. Experimental and computational evaluation of lipidomic in-source fragmentation as a result of postionization with matrix-assisted laser desorption/ionization. Anal. Chem., 96, 16127-16133 (2024); DOI.
Vandermeulen, G., Rosseel, R., Chatonidi, G., Deroover, L., Boets, E. and Verbeke, K. The optimization and validation of a gas chromatography-mass spectrometry method to analyze the concentration of acetate, propionate and butyrate in human plasma or serum. J. Chromatogr. B, 1247, 124299 (2024); DOI.
Verpalen, E.C.J.M., Ehlers, A.M., van Wingaarden, A.C.A., Brouwer, A.J. and Boons, G.J. Synthesis and biological evaluation of lipid A derived from commensal Bacteroides. Org. Biomol. Chem., in press (2024); DOI.
Wang, Z.D. and Xia, Y. Selective enrichment via TiO2 magnetic nanoparticles enables deep profiling of circulating neutral glycosphingolipids. Anal. Chem., in press (2024); DOI.
Wu, Z.S., Du, Y.T., Kirchhausen, T. and He, K.M. Probing and imaging phospholipid dynamics in live cells. Life Metab., 3, loae014 (2024); DOI.
Xu, C.Y., Feng, X.H., Xing, W.H., Tang, C.H., Sun, X.J., Yang, Y.Y. and Zhang, J.M. Identification and quantitation of carbon-carbon double bond isomers of fatty acid in livestock and poultry meat. Food Res. Int., 196, 115119 (2024); DOI.
Yang, H., Yang, T.X., Qi, L.R., Zhang, Y., Xia, Y.H., Wang, Z. and Wang, D.H. Unusual polyunsaturated fatty acids in edible marine worms identified by covalent adduct chemical ionization mass spectrometry. Food Chem., 463, 141287 (2025); DOI.
Yoshida, T. and others. Elevated 12,13-diHOME level in maternal and umbilical cord blood complicated with preeclampsia. Front. Endocrin., 15, 1445475 (2024); DOI.
Zartmann, A., Galano, J.M. and Hammann, S. Analysis of glycerol bound ?-oxo-fatty acids as ?-dioxane-FAME-derivatives. Food Chem., 463, 141223 (2025); DOI.
Zhang, J.G., Lei, J., Liu, X.D., Zhang, N., Wu, L. and Li, Y.S. LC-MS simultaneous profiling of acyl-CoA and acyl-carnitine in dynamic metabolic status. Anal. Chim. Acta, 1329, 343235 (2024); DOI.
Zhou, J.Y.,, Chen, Y.Q., Hu, G., Zhao, H.Y. and Wan, J.B. An integrated strategy for in-depth profiling of N-acylethanolamines in biological samples by UHPLC-HRMS. Anal. Chim. Acta, 1329, 343262 (2024); DOI.

© Data compiled by Bill Christie
Updated: November 6^th, 2024	Contact/credits/disclaimer