LMPD Database

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LMP000760

Gene Information

Entrez Gene ID7376
Gene Namenuclear receptor subfamily 1, group H, member 2
Gene SymbolNR1H2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HGNCCcytoplasm
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:HGNCCnucleus
GO:0034191 IPI:BHF-UCLFapolipoprotein A-I receptor binding
GO:0051117 IPI:BHF-UCLFATPase binding
GO:0003677 TAS:ProtIncFDNA binding
GO:0004879 TAS:ProtIncFligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0000978 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001133 IEA:EnsemblFsequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity
GO:0003707 IEA:InterProFsteroid hormone receptor activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0044255 IEA:EnsemblPcellular lipid metabolic process
GO:0010467 TAS:ReactomePgene expression
GO:0010887 IMP:BHF-UCLPnegative regulation of cholesterol storage
GO:0060336 NAS:BHF-UCLPnegative regulation of interferon-gamma-mediated signaling pathway
GO:0032369 IMP:BHF-UCLPnegative regulation of lipid transport
GO:0010745 IC:BHF-UCLPnegative regulation of macrophage derived foam cell differentiation
GO:0048550 IMP:BHF-UCLPnegative regulation of pinocytosis
GO:0045892 IDA:HGNCPnegative regulation of transcription, DNA-templated
GO:0032270 IMP:BHF-UCLPpositive regulation of cellular protein metabolic process
GO:0010875 IMP:BHF-UCLPpositive regulation of cholesterol efflux
GO:0032376 IDA:BHF-UCLPpositive regulation of cholesterol transport
GO:0045723 IMP:BHF-UCLPpositive regulation of fatty acid biosynthetic process
GO:0051006 IMP:BHF-UCLPpositive regulation of lipoprotein lipase activity
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0010867 IMP:BHF-UCLPpositive regulation of triglyceride biosynthetic process
GO:2000188 ISS:UniProtKBPregulation of cholesterol homeostasis
GO:0048384 IEA:EnsemblPretinoic acid receptor signaling pathway
GO:0006367 TAS:ReactomePtranscription initiation from RNA polymerase II promoter
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_12627Generic Transcription Pathway
REACT_15525Nuclear Receptor transcription pathway