LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP000936

Gene Information

Entrez Gene ID23236
Gene Namephospholipase C, beta 1 (phosphoinositide-specific)
Gene SymbolPLCB1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0000790 ISS:BHF-UCLCnuclear chromatin
GO:0016607 IDA:BHF-UCLCnuclear speck
GO:0005634 NAS:UniProtKBCnucleus
GO:0005509 IEA:InterProFcalcium ion binding
GO:0005516 IPI:BHF-UCLFcalmodulin binding
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0005096 IDA:BHF-UCLFGTPase activator activity
GO:0005546 IDA:BHF-UCLFphosphatidylinositol-4,5-bisphosphate binding
GO:0004435 NAS:UniProtKBFphosphatidylinositol phospholipase C activity
GO:0042803 ISS:BHF-UCLFprotein homodimerization activity
GO:0004871 IEA:UniProtKB-KWFsignal transducer activity
GO:0060466 ISS:BHF-UCLPactivation of meiosis involved in egg activation
GO:0021987 ISS:BHF-UCLPcerebral cortex development
GO:0045444 IEA:EnsemblPfat cell differentiation
GO:0000086 ISS:BHF-UCLPG2/M transition of mitotic cell cycle
GO:0007215 ISS:BHF-UCLPglutamate receptor signaling pathway
GO:0007213 ISS:BHF-UCLPG-protein coupled acetylcholine receptor signaling pathway
GO:0043647 TAS:ReactomePinositol phosphate metabolic process
GO:0048009 ISS:BHF-UCLPinsulin-like growth factor receptor signaling pathway
GO:0035722 IDA:BHF-UCLPinterleukin-12-mediated signaling pathway
GO:0035723 IDA:BHF-UCLPinterleukin-15-mediated signaling pathway
GO:0070498 IDA:BHF-UCLPinterleukin-1-mediated signaling pathway
GO:0035556 IEA:InterProPintracellular signal transduction
GO:0016042 IEA:UniProtKB-KWPlipid catabolic process
GO:0007613 ISS:BHF-UCLPmemory
GO:2000438 ISS:BHF-UCLPnegative regulation of monocyte extravasation
GO:0045892 ISS:BHF-UCLPnegative regulation of transcription, DNA-templated
GO:0046488 ISS:BHF-UCLPphosphatidylinositol metabolic process
GO:2000344 ISS:BHF-UCLPpositive regulation of acrosome reaction
GO:2000560 ISS:BHF-UCLPpositive regulation of CD24 biosynthetic process
GO:0048639 ISS:BHF-UCLPpositive regulation of developmental growth
GO:0040019 ISS:BHF-UCLPpositive regulation of embryonic development
GO:1900087 ISS:BHF-UCLPpositive regulation of G1/S transition of mitotic cell cycle
GO:0043547 IDA:GOCPpositive regulation of GTPase activity
GO:0032735 ISS:BHF-UCLPpositive regulation of interleukin-12 production
GO:0046330 IDA:BHF-UCLPpositive regulation of JNK cascade
GO:0045663 ISS:BHF-UCLPpositive regulation of myoblast differentiation
GO:0045893 ISS:BHF-UCLPpositive regulation of transcription, DNA-templated
GO:0080154 ISS:BHF-UCLPregulation of fertilization
GO:0008277 ISS:BHF-UCLPregulation of G-protein coupled receptor protein signaling pathway
GO:0007165 NAS:UniProtKBPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007268 TAS:ReactomePsynaptic transmission
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04022cGMP-PKG signaling pathway
hsa04750Inflammatory mediator regulation of TRP channels
hsa04921Oxytocin signaling pathway
hsa04611Platelet activation