LMPD Database

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LMP001889

Gene Information

Entrez Gene ID10062
Gene Namenuclear receptor subfamily 1, group H, member 3
Gene SymbolNR1H3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000790 IDA:BHF-UCLCnuclear chromatin
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 TAS:ProtIncCnucleus
GO:0015485 TAS:BHF-UCLFcholesterol binding
GO:0003677 TAS:ProtIncFDNA binding
GO:0004879 TAS:ProtIncFligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0000978 IEA:EnsemblFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA:EnsemblFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003707 IEA:InterProFsteroid hormone receptor activity
GO:0032810 IDA:UniProtKBFsterol response element binding
GO:0003713 TAS:ProtIncFtranscription coactivator activity
GO:0044212 IDA:BHF-UCLFtranscription regulatory region DNA binding
GO:0008270 IEA:InterProFzinc ion binding
GO:0043277 IMP:UniProtKBPapoptotic cell clearance
GO:0044255 IEA:EnsemblPcellular lipid metabolic process
GO:0071222 IDA:BHF-UCLPcellular response to lipopolysaccharide
GO:0042632 ISS:BHF-UCLPcholesterol homeostasis
GO:0010467 TAS:ReactomePgene expression
GO:0055088 ISS:BHF-UCLPlipid homeostasis
GO:0010887 IMP:BHF-UCLPnegative regulation of cholesterol storage
GO:0050728 ISS:BHF-UCLPnegative regulation of inflammatory response
GO:0060336 NAS:BHF-UCLPnegative regulation of interferon-gamma-mediated signaling pathway
GO:0032369 IMP:BHF-UCLPnegative regulation of lipid transport
GO:0043031 ISS:BHF-UCLPnegative regulation of macrophage activation
GO:0010745 IC:BHF-UCLPnegative regulation of macrophage derived foam cell differentiation
GO:0090188 ISS:BHF-UCLPnegative regulation of pancreatic juice secretion
GO:0048550 IMP:BHF-UCLPnegative regulation of pinocytosis
GO:0045861 IEA:EnsemblPnegative regulation of proteolysis
GO:0090341 ISS:BHF-UCLPnegative regulation of secretion of lysosomal enzymes
GO:0000122 ISS:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:0032270 IMP:BHF-UCLPpositive regulation of cellular protein metabolic process
GO:0010875 IDA:BHF-UCLPpositive regulation of cholesterol efflux
GO:2000189 IDA:BHF-UCLPpositive regulation of cholesterol homeostasis
GO:0032376 IDA:BHF-UCLPpositive regulation of cholesterol transport
GO:0045723 IMP:BHF-UCLPpositive regulation of fatty acid biosynthetic process
GO:0051006 IMP:BHF-UCLPpositive regulation of lipoprotein lipase activity
GO:0010870 IDA:BHF-UCLPpositive regulation of receptor biosynthetic process
GO:0034145 IDA:BHF-UCLPpositive regulation of toll-like receptor 4 signaling pathway
GO:0045893 IMP:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0010867 IMP:BHF-UCLPpositive regulation of triglyceride biosynthetic process
GO:2000188 ISS:UniProtKBPregulation of cholesterol homeostasis
GO:0042752 TAS:BHF-UCLPregulation of circadian rhythm
GO:0032570 IDA:BHF-UCLPresponse to progesterone
GO:0055092 ISS:BHF-UCLPsterol homeostasis
GO:0006367 TAS:ReactomePtranscription initiation from RNA polymerase II promoter
GO:0070328 ISS:BHF-UCLPtriglyceride homeostasis
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04932Non-alcoholic fatty liver disease (NAFLD)