LMPD Database

LMP002064

Gene Information

Entrez Gene ID9536
Gene Nameprostaglandin E synthase
Gene SymbolPTGES
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 IDA:UniProtKBCintegral component of membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0005641 IEA:EnsemblCnuclear envelope lumen
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0043295 IDA:UniProtKBFglutathione binding
GO:0050220 IDA:UniProtKBFprostaglandin-E synthase activity
GO:0002526 IEA:EnsemblPacute inflammatory response
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0002544 IEA:EnsemblPchronic inflammatory response
GO:0019371 TAS:ReactomePcyclooxygenase pathway
GO:0008285 IEA:EnsemblPnegative regulation of cell proliferation
GO:0001516 IDA:UniProtKBPprostaglandin biosynthetic process
GO:0006693 TAS:ProtIncPprostaglandin metabolic process
GO:0051592 IEA:EnsemblPresponse to calcium ion
GO:0034097 IEA:EnsemblPresponse to cytokine
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
GO:0032526 IEA:EnsemblPresponse to retinoic acid
GO:0007165 NAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00590Arachidonic acid metabolism
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_150149Synthesis of Prostaglandins (PG) and Thromboxanes (TX)