LMPD Database

LMP002551

Gene Information

Entrez Gene ID	19013
Gene Name	peroxisome proliferator activated receptor alpha
Gene Symbol	Ppara
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	TAS:MGI	C	nucleus
GO:0003677	IDA:MGI	F	DNA binding
GO:0008144	ISS:UniProtKB	F	drug binding
GO:0004879	IEA:Ensembl	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0008289	IDA:UniProtKB	F	lipid binding
GO:0046982	TAS:UniProtKB	F	protein heterodimerization activity
GO:0004872	IDA:MGI	F	receptor activity
GO:0000978	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001077	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001190	IDA:MGI	F	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0043565	IDA:UniProtKB	F	sequence-specific DNA binding
GO:0003700	IMP:UniProtKB	F	sequence-specific DNA binding transcription factor activity
GO:0003707	TAS:MGI	F	steroid hormone receptor activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0035095	IEA:Ensembl	P	behavioral response to nicotine
GO:0032922	IDA:UniProtKB	P	circadian regulation of gene expression
GO:0070166	IMP:MGI	P	enamel mineralization
GO:0008544	IMP:MGI	P	epidermis development
GO:0006631	IMP:MGI	P	fatty acid metabolic process
GO:0006006	TAS:MGI	P	glucose metabolic process
GO:0007507	IEA:Ensembl	P	heart development
GO:0006629	TAS:MGI	P	lipid metabolic process
GO:0042157	IEA:Ensembl	P	lipoprotein metabolic process
GO:0032099	IMP:UniProtKB	P	negative regulation of appetite
GO:0045776	IEA:Ensembl	P	negative regulation of blood pressure
GO:0010887	IEA:Ensembl	P	negative regulation of cholesterol storage
GO:1901215	IEA:Ensembl	P	negative regulation of neuron death
GO:0032091	IEA:Ensembl	P	negative regulation of protein binding
GO:0010871	IEA:Ensembl	P	negative regulation of receptor biosynthetic process
GO:0010891	IEA:Ensembl	P	negative regulation of sequestering of triglyceride
GO:2000678	IEA:Ensembl	P	negative regulation of transcription regulatory region DNA binding
GO:0046321	IMP:BHF-UCL	P	positive regulation of fatty acid oxidation
GO:0045722	IMP:MGI	P	positive regulation of gluconeogenesis
GO:0045893	IMP:UniProtKB	P	positive regulation of transcription, DNA-templated
GO:0045944	IDA:MGI	P	positive regulation of transcription from RNA polymerase II promoter
GO:0072366	IEA:Ensembl	P	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752	IDA:UniProtKB	P	regulation of circadian rhythm
GO:0019217	IMP:MGI	P	regulation of fatty acid metabolic process
GO:0010468	IMP:MGI	P	regulation of gene expression
GO:0072363	IEA:Ensembl	P	regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoter
GO:0072369	IEA:Ensembl	P	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0006355	TAS:MGI	P	regulation of transcription, DNA-templated
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0032868	IEA:Ensembl	P	response to insulin
GO:0042060	IMP:MGI	P	wound healing

KEGG Pathway Links

KEGG Pathway ID	Description
mmu04024	cAMP signaling pathway
mmu04932	Non-alcoholic fatty liver disease (NAFLD)