LMPD Database

LMP006729

Record overview

LMPD ID	LMP006729
Gene ID	5733
Species	Homo sapiens (Human)
Gene Name	prostaglandin E receptor 3 (subtype EP3)
Gene Symbol	PTGER3
Synonyms	EP3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3e; PGE2-R
Alternate names	prostaglandin E2 receptor EP3 subtype; prostanoid EP3 receptor; PGE receptor, EP3 subtype; PGE2 receptor EP3 subtype; prostaglandin receptor (PGE-2); prostaglandin E receotor EP3 subtype 3 isoform
Chromosome	1
Map Location	1p31.2
Summary	The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Orthologs	View orthologs and multiple alignments for PTGER3

Proteins

prostaglandin E2 receptor EP3 subtype isoform 4

Refseq ID:	NP_001119516
Protein GI:	186659506
UniProt ID:	P43115
mRNA ID:	NM_001126044
Length:	390
RefSeq Status:	REVIEWED

prostaglandin E2 receptor EP3 subtype isoform 4
`MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLER`

Refseq ID:	NP_942007
Protein GI:	38505178
UniProt ID:	P43115
mRNA ID:	NM_198714
Length:	390
RefSeq Status:	REVIEWED

prostaglandin E2 receptor EP3 subtype isoform 4
Protein sequence is identical to GI:186659506 (mRNA isoform)

Refseq ID:	NP_942012
Protein GI:	38505188
UniProt ID:	P43115
mRNA ID:	NM_198719
Length:	390
RefSeq Status:	REVIEWED

prostaglandin E2 receptor EP3 subtype isoform 5
Protein sequence is identical to GI:186659506 (mRNA isoform)

Refseq ID:	NP_942008
Protein GI:	38505180
UniProt ID:	P43115
mRNA ID:	NM_198715
Length:	388
RefSeq Status:	REVIEWED

prostaglandin E2 receptor EP3 subtype isoform 6
`MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQVANAVSSCSNDGQKGQPISLSNEIIQTEA`

Refseq ID:	NP_942009
Protein GI:	38505182
UniProt ID:	P43115
mRNA ID:	NM_198716
Length:	374
RefSeq Status:	REVIEWED

prostaglandin E2 receptor EP3 subtype isoform 7
`MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQEEFWGN`

Refseq ID:	NP_942010
Protein GI:	38505184
UniProt ID:	P43115
mRNA ID:	NM_198717
Length:	365
RefSeq Status:	REVIEWED

prostaglandin E2 receptor EP3 subtype isoform 8
`MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQEEFWGN`

Refseq ID:	NP_942011
Protein GI:	38505186
UniProt ID:	O00325
mRNA ID:	NM_198718
Length:	418
RefSeq Status:	REVIEWED

MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDL
VGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYT
VQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEME
VLVSSINVYTRISTVKTE