LMPD Database

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LMP007131

Gene Information

Entrez Gene ID852818
Gene Namepyruvate carboxylase 1
Gene SymbolPYC1
SpeciesSaccharomyces cerevisiae S288c
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:SGDCcytosol
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004075 IEA:InterProFbiotin carboxylase activity
GO:0003677 IEA:InterProFDNA binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004736 IMP:SGDFpyruvate carboxylase activity
GO:0006094 IMP:SGDPgluconeogenesis
KEGG Pathway Links
KEGG Pathway IDDescription
ko01230Biosynthesis of amino acids
sce01230Biosynthesis of amino acids
ko01200Carbon metabolism
sce01200Carbon metabolism
ko00020Citrate cycle (TCA cycle)
sce00020Citrate cycle (TCA cycle)
sce01100Metabolic pathways
ko00620Pyruvate metabolism
sce00620Pyruvate metabolism
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
ASPBIO-PWYaspartate biosynthesis
GLUCONEO-YEAST-PWYgluconeogenesis
TCA-EUK-PWY-YEASTTCA cycle, aerobic respiration
REACTOME Pathway Links
REACTOME Pathway IDDescription
5618669Biotin transport and metabolism
5618374Defective AMN causes hereditary megaloblastic anemia 1
5618384Defective BTD causes biotidinase deficiency
5618383Defective CD320 causes methylmalonic aciduria
5618375Defective CUBN causes hereditary megaloblastic anemia 1
5618372Defective GIF causes intrinsic factor deficiency
5618386Defective HLCS causes multiple carboxylase deficiency
5618373Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
5618381Defective MMAA causes methylmalonic aciduria type cblA
5618378Defective MMAB causes methylmalonic aciduria type cblB
5618380Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
5618379Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
5618377Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
5618376Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
5618382Defective MUT causes methylmalonic aciduria mut type
5618369Defective TCN2 causes hereditary megaloblastic anemia
5618385Defects in biotin (Btn) metabolism
5618370Defects in cobalamin (B12) metabolism
5618371Defects in vitamin and cofactor metabolism
5618026Disease
5618020Gluconeogenesis
5618021Glucose metabolism
5618025Glycogen storage diseases
5618023Metabolism
5618022Metabolism of carbohydrates
5618368Metabolism of vitamins and cofactors
5618367Metabolism of water-soluble vitamins and cofactors
5618024Myoclonic epilepsy of Lafora