LMPD Database

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LMP009785

UniProt Annotations

Entry Information
Gene Nameacyl-coenzyme A oxidase 4
Protein EntryACOX4_ARATH
UniProt IDQ96329
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=8.3 uM for hexanoyl-CoA; pH dependence: Optimum pH is 8.5-9.0.;
Catalytic ActivityAcyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2).
CofactorName=FAD; Xref=ChEBI:CHEBI:57692;
Developmental StageInduced by seed imbibition with a peak at day 5 to 7. Decreases after illumination but still detectable 5 days after illumination.
FunctionCatalyzes the desaturation of short-chain acyl-CoAs to 2-trans-enoyl-CoAs. Active on butyryl-CoA (C4), hexanoyl-CoA (C6), and octanoyl-CoA (C8). Has no activity as acyl-CoA dehydrogenase or on crotonyl-CoA (an unsaturated C4:1 carbocyclic ester) or glutaryl-CoA (a dicarboxylic ester).
InductionInduced by dehydration and abscisic acid (ABA). {ECO:0000269|PubMed:15141068}.
SimilarityBelongs to the acyl-CoA dehydrogenase family. {ECO:0000305}.
Subcellular LocationGlyoxysome. Peroxisome.
SubunitHomotetramer. {ECO:0000269|PubMed:16887802}.
Tissue SpecificityParticularly abundant in etiolated cotyledons. Also present in flowers, roots and siliques, but not detected in green cotyledons, rosette leaves and stems. {ECO:0000269|PubMed:10212254}.