LMPD Database

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LMP011312

Record overview

LMPD IDLMP011312
Gene ID829616
SpeciesArabidopsis thaliana (Arabidopsis)
Gene NameSqualene synthase 1
Gene SymbolSQS1
SynonymsERG9; SQS1; SQUALENE SYNTHASE; squalene synthase 1; T4L20.220; T4L20_220
Alternate namesSqualene synthase 1
Chromosome4
EC Number2.5.1.21
SummaryEncodes squalene synthase, which converts two molecules of farnesyl diphosphate (FPP) into squalene via an intermediate: presqualene diphosphate (PSPP). It is generally thought to be one of the key enzymes of sterol biosynthesis, since it catalyzes the first pathway-specific reaction of the sterol branch of the isoprenoid pathway.
OrthologsView orthologs and multiple alignments for SQS1

Proteins

Squalene synthase 1
Refseq ID:NP_195190
Protein GI:15236168
UniProt ID:P53799
mRNA ID:NM_119630
Length:410
RefSeq Status:REVIEWED
MGSLGTMLRYPDDIYPLLKMKRAIEKAEKQIPPEPHWGFCYSMLHKVSRSFSLVIQQLNTELRNAVCVFYLVLRALDTVEDDTSIPTDEKVPILIAFHRH
IYDTDWHYSCGTKEYKILMDQFHHVSAAFLELEKGYQEAIEEITRRMGAGMAKFICQEVETVDDYDEYCHYVAGLVGLGLSKLFLAAGSEVLTPDWEAIS
NSMGLFLQKTNIIRDYLEDINEIPKSRMFWPREIWGKYADKLEDLKYEENTNKSVQCLNEMVTNALMHIEDCLKYMVSLRDPSIFRFCAIPQIMAIGTLA
LCYNNEQVFRGVVKLRRGLTAKVIDRTKTMADVYGAFYDFSCMLKTKVDKNDPNASKTLNRLEAVQKLCRDAGVLQNRKSYVNDKGQPNSVFIIMVVILL
AIVFAYLRAN