LMPD Database

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LMP011312

UniProt Annotations

Entry Information
Gene NameSqualene synthase 1
Protein EntryFDFT_ARATH
UniProt IDP53799
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic Activity2 farnesyl diphosphate + NAD(P)H = squalene + 2 diphosphate + NAD(P)(+).
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420;
PathwayTerpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.
SimilarityBelongs to the phytoene/squalene synthase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue SpecificityExpressed in all tissues analyzed (inflorescences, leaves, stems and roots). Highly expressed in roots. {ECO:0000269|PubMed:9363754}.