LMPD Database

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LMP012378

Gene Information

Entrez Gene ID100137049
Gene Namephospholipase A2, group IVB (cytosolic)
Gene SymbolPLA2G4B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:UniProtKBCcytosol
GO:0005768 IEA:UniProtKB-KWCendosome
GO:0005576 TAS:UniProtKBCextracellular region
GO:0005743 TAS:ReactomeCmitochondrial inner membrane
GO:0047498 IDA:UniProtKBFcalcium-dependent phospholipase A2 activity
GO:0005544 NAS:UniProtKBFcalcium-dependent phospholipid binding
GO:0005509 NAS:UniProtKBFcalcium ion binding
GO:0004622 NAS:UniProtKBFlysophospholipase activity
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0019369 NAS:UniProtKBParachidonic acid metabolic process
GO:0019722 NAS:UniProtKBPcalcium-mediated signaling
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0046475 IDA:UniProtKBPglycerophospholipid catabolic process
GO:0006954 NAS:UniProtKBPinflammatory response
GO:0007567 NAS:UniProtKBPparturition
GO:0006654 TAS:ReactomePphosphatidic acid biosynthetic process
GO:0036151 TAS:ReactomePphosphatidylcholine acyl-chain remodeling
GO:0036152 TAS:ReactomePphosphatidylethanolamine acyl-chain remodeling
GO:0036148 TAS:ReactomePphosphatidylglycerol acyl-chain remodeling
GO:0036150 TAS:ReactomePphosphatidylserine acyl-chain remodeling
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00592alpha-Linolenic acid metabolism
ko00592alpha-Linolenic acid metabolism
hsa00590Arachidonic acid metabolism
ko00590Arachidonic acid metabolism
hsa00565Ether lipid metabolism
ko00565Ether lipid metabolism
hsa04664Fc epsilon RI signaling pathway
ko04664Fc epsilon RI signaling pathway
hsa04666Fc gamma R-mediated phagocytosis
ko04666Fc gamma R-mediated phagocytosis
hsa04724Glutamatergic synapse
ko04724Glutamatergic synapse
hsa00564Glycerophospholipid metabolism
ko00564Glycerophospholipid metabolism
hsa04912GnRH signaling pathway
ko04912GnRH signaling pathway
hsa04750Inflammatory mediator regulation of TRP channels
ko04750Inflammatory mediator regulation of TRP channels
hsa00591Linoleic acid metabolism
ko00591Linoleic acid metabolism
hsa04730Long-term depression
ko04730Long-term depression
hsa04010MAPK signaling pathway
ko04010MAPK signaling pathway
hsa01100Metabolic pathways
hsa04913Ovarian steroidogenesis
ko04913Ovarian steroidogenesis
hsa04921Oxytocin signaling pathway
ko04921Oxytocin signaling pathway
hsa04611Platelet activation
hsa04014Ras signaling pathway
hsa04726Serotonergic synapse
hsa04270Vascular smooth muscle contraction
ko04270Vascular smooth muscle contraction
hsa04370VEGF signaling pathway
ko04370VEGF signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120829Acyl chain remodelling of PC
REACT_121369Acyl chain remodelling of PE
REACT_121324Acyl chain remodelling of PG
REACT_121384Acyl chain remodelling of PS
REACT_121401Glycerophospholipid biosynthesis
REACT_120977Hydrolysis of LPC
REACT_18368IRE1alpha activates chaperones
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_17015Metabolism of proteins
REACT_120870Phospholipid metabolism
REACT_120906Synthesis of PA
REACT_18356Unfolded Protein Response (UPR)
REACT_18273XBP1(S) activates chaperone genes