LMPD Database

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LMP012477

Gene Information

Entrez Gene ID25149
Gene Nameestrogen receptor 2 (ER beta)
Gene SymbolEsr2
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005929 IDA:RGDCcilium
GO:0005737 IDA:RGDCcytoplasm
GO:0005739 IDA:MGICmitochondrion
GO:0043025 IDA:RGDCneuronal cell body
GO:0043005 IDA:RGDCneuron projection
GO:0005634 IDA:RGDCnucleus
GO:0043204 IDA:RGDCperikaryon
GO:0048471 IDA:RGDCperinuclear region of cytoplasm
GO:0005886 IDA:RGDCplasma membrane
GO:0032993 IDA:RGDCprotein-DNA complex
GO:0001046 IDA:RGDFcore promoter sequence-specific DNA binding
GO:0008144 IPI:RGDFdrug binding
GO:0019899 IPI:RGDFenzyme binding
GO:0030284 IDA:RGDFestrogen receptor activity
GO:0034056 IDA:RGDFestrogen response element binding
GO:0042562 IDA:RGDFhormone binding
GO:0042975 IPI:RGDFperoxisome proliferator activated receptor binding
GO:0000978 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0043565 IDA:RGDFsequence-specific DNA binding
GO:0005496 IDA:UniProtKBFsteroid binding
GO:1990239 IPI:RGDFsteroid hormone binding
GO:0003707 IDA:RGDFsteroid hormone receptor activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0021764 IEP:RGDPamygdala development
GO:0001662 IDA:RGDPbehavioral fear response
GO:0035690 IEP:RGDPcellular response to drug
GO:0071392 IEP:RGDPcellular response to estradiol stimulus
GO:0071259 IEP:RGDPcellular response to magnetism
GO:0071407 IEP:RGDPcellular response to organic cyclic compound
GO:0021549 IEP:RGDPcerebellum development
GO:0060209 IMP:RGDPestrus
GO:0008585 IEP:RGDPfemale gonad development
GO:0021854 IEP:RGDPhypothalamus development
GO:0030520 TAS:RGDPintracellular estrogen receptor signaling pathway
GO:0030518 IDA:RGDPintracellular steroid hormone receptor signaling pathway
GO:0007611 IMP:RGDPlearning or memory
GO:0008584 IEP:RGDPmale gonad development
GO:0048521 IDA:RGDPnegative regulation of behavior
GO:0060548 IMP:RGDPnegative regulation of cell death
GO:0050680 IDA:RGDPnegative regulation of epithelial cell proliferation
GO:2000252 IMP:RGDPnegative regulation of feeding behavior
GO:1901215 IDA:RGDPnegative regulation of neuron death
GO:2000378 IMP:RGDPnegative regulation of reactive oxygen species metabolic process
GO:0048662 IMP:RGDPnegative regulation of smooth muscle cell proliferation
GO:0000122 IDA:RGDPnegative regulation of transcription from RNA polymerase II promoter
GO:0001541 IEP:RGDPovarian follicle development
GO:0043065 IDA:RGDPpositive regulation of apoptotic process
GO:0045742 IMP:RGDPpositive regulation of epidermal growth factor receptor signaling pathway
GO:0070374 IDA:RGDPpositive regulation of ERK1 and ERK2 cascade
GO:0051091 ISS:UniProtKBPpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0045893 IDA:RGDPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:NTNU_SBPpositive regulation of transcription from RNA polymerase II promoter
GO:0030850 IEP:RGDPprostate gland development
GO:0043523 IDA:RGDPregulation of neuron apoptotic process
GO:0014823 IEP:RGDPresponse to activity
GO:0071548 IEP:RGDPresponse to dexamethasone
GO:0042493 IEP:RGDPresponse to drug
GO:0032355 IEP:RGDPresponse to estradiol
GO:0043627 IEP:RGDPresponse to estrogen
GO:0045471 IEP:RGDPresponse to ethanol
GO:0033595 IEP:RGDPresponse to genistein
GO:0009725 IEP:RGDPresponse to hormone
GO:0044752 IEP:RGDPresponse to human chorionic gonadotropin
GO:0017085 IEP:RGDPresponse to insecticide
GO:0031667 IEP:RGDPresponse to nutrient levels
GO:0014070 IEP:RGDPresponse to organic cyclic compound
GO:1902074 IEP:RGDPresponse to salt
GO:0033574 IMP:RGDPresponse to testosterone
GO:0009414 IEP:RGDPresponse to water deprivation
GO:0060009 IEP:RGDPSertoli cell development
GO:0060011 IMP:RGDPSertoli cell proliferation
KEGG Pathway Links
KEGG Pathway IDDescription
ko04915Estrogen signaling pathway
rno04915Estrogen signaling pathway
ko04917Prolactin signaling pathway
rno04917Prolactin signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953330Gene Expression
5953833Generic Transcription Pathway
5954147Nuclear Receptor transcription pathway