LMPD Database

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LMP013314

Gene Information

Entrez Gene ID309419
Gene Namephosphatidylinositol-4-phosphate 5-kinase, type I, beta
Gene SymbolPip5k1b
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0001931 IEA:EnsemblCuropod
GO:0016308 IEA:UniProtKB-ECF1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
KEGG Pathway Links
KEGG Pathway IDDescription
ko04144Endocytosis
rno04144Endocytosis
ko04666Fc gamma R-mediated phagocytosis
rno04666Fc gamma R-mediated phagocytosis
ko04510Focal adhesion
rno04510Focal adhesion
ko00562Inositol phosphate metabolism
rno00562Inositol phosphate metabolism
M00130Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
rno01100Metabolic pathways
ko04070Phosphatidylinositol signaling system
rno04070Phosphatidylinositol signaling system
ko04810Regulation of actin cytoskeleton
rno04810Regulation of actin cytoskeleton
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953253Disease
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5954026misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
5953474Phospholipid metabolism
5954478PI Metabolism
5954027RNF mutants show enhanced WNT signaling and proliferation
5953803Signaling by Wnt
5953965Signaling by WNT in cancer
5953381Signal Transduction
5954499Synthesis of PIPs at the plasma membrane
5954025TCF dependent signaling in response to WNT
5954031WNT mediated activation of DVL
5954028XAV939 inhibits tankyrase, stabilizing AXIN