LMPD Database

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LMP014734

Gene Information

Entrez Gene ID703407
Gene Nameprostaglandin I2 (prostacyclin) synthase
Gene SymbolPTGIS
SpeciesMacaca mulatta
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005901 ISS:UniProtKBCcaveola
GO:0005783 ISS:UniProtKBCendoplasmic reticulum
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0005615 ISS:UniProtKBCextracellular space
GO:0005634 ISS:UniProtKBCnucleus
GO:0020037 IBA:RefGenomeFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0004497 IEA:InterProFmonooxygenase activity
GO:0016705 IEA:InterProFoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0008116 ISS:UniProtKBFprostaglandin-I synthase activity
GO:0097190 IEA:EnsemblPapoptotic signaling pathway
GO:0071456 ISS:UniProtKBPcellular response to hypoxia
GO:0071347 ISS:UniProtKBPcellular response to interleukin-1
GO:0071354 ISS:UniProtKBPcellular response to interleukin-6
GO:0050728 ISS:UniProtKBPnegative regulation of inflammatory response
GO:0032088 ISS:UniProtKBPnegative regulation of NF-kappaB transcription factor activity
GO:0045019 ISS:UniProtKBPnegative regulation of nitric oxide biosynthetic process
GO:0045766 ISS:UniProtKBPpositive regulation of angiogenesis
GO:1900119 ISS:UniProtKBPpositive regulation of execution phase of apoptosis
GO:0035360 ISS:UniProtKBPpositive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0001516 ISS:UniProtKBPprostaglandin biosynthetic process
GO:0042981 IBA:RefGenomePregulation of apoptotic process
KEGG Pathway Links
KEGG Pathway IDDescription
ko00590Arachidonic acid metabolism
mcc00590Arachidonic acid metabolism
mcc01100Metabolic pathways