LMPD Database

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LMP014734

UniProt Annotations

Entry Information
Gene Nameprostaglandin I2 (prostacyclin) synthase
Protein EntryF7F0C0_MACMU
UniProt IDF7F0C0
SpeciesRhesus monkey
Comments
Comment typeDescription
Catalytic Activity(5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15- hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-6,9-alpha-epoxy-11- alpha,15-dihydroxyprosta-5,13-dienoate.
CautionThe sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
CofactorNote=Heme group. ;
FunctionCatalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
SimilarityBelongs to the cytochrome P450 family.
Subcellular LocationEndoplasmic reticulum membrane