LMPD Database

LMP001124

Gene Information

Entrez Gene ID	2101
Gene Name	estrogen-related receptor alpha
Gene Symbol	ESRRA
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0045171	IDA:HPA	C	intercellular bridge
GO:0015630	IDA:HPA	C	microtubule cytoskeleton
GO:0005730	IDA:HPA	C	nucleolus
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	IDA:HPA	C	nucleus
GO:0003677	TAS:ProtInc	F	DNA binding
GO:0004879	TAS:ProtInc	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0019904	IPI:UniProtKB	F	protein domain specific binding
GO:0000978	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001077	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0043565	IDA:UniProtKB	F	sequence-specific DNA binding
GO:0005496	IEA:InterPro	F	steroid binding
GO:0003707	IEA:InterPro	F	steroid hormone receptor activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0051216	IEA:Ensembl	P	cartilage development
GO:0010467	TAS:Reactome	P	gene expression
GO:0030522	TAS:GOC	P	intracellular receptor signaling pathway
GO:0045944	ISS:BHF-UCL	P	positive regulation of transcription from RNA polymerase II promoter
GO:0042127	IEA:Ensembl	P	regulation of cell proliferation
GO:0045667	IEA:Ensembl	P	regulation of osteoblast differentiation
GO:0045670	IEA:Ensembl	P	regulation of osteoclast differentiation
GO:0006355	IMP:UniProtKB	P	regulation of transcription, DNA-templated
GO:0006367	TAS:Reactome	P	transcription initiation from RNA polymerase II promoter

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_116145	PPARA activates gene expression
REACT_200608	Transcriptional activation of mitochondrial biogenesis