LMPD Database

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LMP012510

Record overview

LMPD IDLMP012510
Gene ID25428
SpeciesMacaca mulata (Rhesus monkey)
Gene Namecytochrome P450, family 7, subfamily a, polypeptide 1
Gene SymbolCyp7a1
SynonymsCHAP; CYP7; CYP7S1;
Alternate namescholesterol 7-alpha-monooxygenase; CYPVII; cytochrome P450, 7a1; cholesterol 7-alpha hydroxylase; cholesterol 7-alpha-hydroxylase; cytochrome P450 (cholesterol hydroxylase 7 alpha);
Chromosome5
Map Location5q12
EC Number1.14.13.17
Summarycatalyzes the conversion of cholesterol, NADPH, and oxygen to 7-alpha-hydroxycholesterol, NADP(+) and water; plays a role in bile acid biosynthesis and cholesterol metabolism [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Cyp7a1

Proteins

cholesterol 7-alpha-monooxygenase
Refseq ID:NP_037074
Protein GI:7549754
UniProt ID:P18125
mRNA ID:NM_012942
Length:503
RefSeq Status:
MMTISLIWGIAVLVSCCIWFIVGIRRRKAGEPPLENGLIPYLGCALKFGSNPLEFLRANQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKF
HYTTSAKAFGHRSIDPNDGNTTENINNTFTKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSNAWVTEGMYAFCYRVMFEAGYLTLFGRDISKTDTQKA
LILNNLDNFKQFDQVFPALVAGLPIHLFKTAHKAREKLAEGLKHKNLCVRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLAILWASQANTIPATFWSLFQ
MIRSPEAMKAASEEVSGALQSAGQELSSGGSAIYLDQVQLNDLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDMIALYPQLMHLDPEI
YPDPLTFKYDRYLDESGKAKTTFYSNGNKLKCFYMPFGSGATICPGRLFAVQEIKQFLILMLSCFELEFVESQVKCPPLDQSRAGLGILPPLHDIEFKYK
LKH