LMPD Database

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LMP012510

Gene Information

Entrez Gene ID25428
Gene Namecytochrome P450, family 7, subfamily a, polypeptide 1
Gene SymbolCyp7a1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IEA:UniProtKB-KWCendoplasmic reticulum
GO:0043231 IDA:UniProtKBCintracellular membrane-bounded organelle
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0008123 IDA:UniProtKBFcholesterol 7-alpha-monooxygenase activity
GO:0020037 IEA:InterProFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0006699 IDA:UniProtKBPbile acid biosynthetic process
GO:0071397 IDA:UniProtKBPcellular response to cholesterol
GO:0071333 ISS:UniProtKBPcellular response to glucose stimulus
GO:0006707 IDA:UniProtKBPcholesterol catabolic process
GO:0042632 IDA:UniProtKBPcholesterol homeostasis
GO:0070857 IDA:UniProtKBPregulation of bile acid biosynthetic process
KEGG Pathway Links
KEGG Pathway IDDescription
ko04976Bile secretion
rno04976Bile secretion
rno01100Metabolic pathways
ko03320PPAR signaling pathway
rno03320PPAR signaling pathway
ko00120Primary bile acid biosynthesis
rno00120Primary bile acid biosynthesis
ko00140Steroid hormone biosynthesis
rno00140Steroid hormone biosynthesis
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-6061bile acid biosynthesis, neutral pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953720Bile acid and bile salt metabolism
5953258Biological oxidations
5953485Cytochrome P450 - arranged by substrate type
5953932Endogenous sterols
5953288Fatty acid, triacylglycerol, and ketone body metabolism
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5953326Phase 1 - Functionalization of compounds
5954333PPARA activates gene expression
5954222Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
5953930Synthesis of bile acids and bile salts
5953931Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol