Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Biosynthesis of amino acids (mmu01230)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
4933405O
20Rik
KLA  ATP  ATP+KLA
NM_172901 RIKEN cDNA 4933405O20 gene (4933405O20Rik), mRNA [NM_172901] KLA .98 .99 1.01 1.07 1.03 1.01 1.03
ATP .95 .97 .99 .96 .99 1.01 1.02
KLA/ATP .93 1.01 .99 .98 .98 .92 .96
AK077927
KLA  ATP  ATP+KLA
AK077927 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030447B09 product:unclassifiable, full insert sequence. [AK077927] KLA 3.15 2.64 2.14 1.56 1.86 1.87 1.23
ATP .91 .63 .45 .45 1.18 1.41 .90
KLA/ATP 2.53 2.04 1.88 .94 1.59 1.96 1.21
AK169742
KLA  ATP  ATP+KLA
AK169742 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430016M08 product:glyceraldehyde-3-phosphate dehydrogenase, full insert sequence. [AK169742] KLA .82 .94 .91 .90 1.13 .93 1.79
ATP .59 .66 .72 .89 1.88 1.96 1.26
KLA/ATP .75 .69 .70 .84 1.00 1.13 1.46
AU021838
KLA  ATP  ATP+KLA
AK032842 12 days embryo male wolffian duct includes surrounding region cDNA, RIKEN full-length enriched library, clone:6720461H18 product:unclassifiable, full insert sequence [AK032842] KLA .87 .74 .81 .58 .51 .52 .55
ATP 1.00 1.03 1.09 .76 .43 .45 .42
KLA/ATP .81 .82 .68 .56 .38 .37 .31
Aadat
KLA  ATP  ATP+KLA
NM_011834 aminoadipate aminotransferase (Aadat), mRNA [NM_011834] KLA 1.05 1.06 1.04 .98 1.00 1.04 .98
ATP .98 .99 1.10 1.03 1.00 1.04 1.03
KLA/ATP 1.05 1.09 1.07 1.04 .97 1.06 1.05
Aco1
KLA  ATP  ATP+KLA
NM_007386 aconitase 1 (Aco1), mRNA [NM_007386] KLA .82 .85 .80 .78 .73 .74 .84
ATP 1.02 1.07 1.04 .96 .95 .88 .83
KLA/ATP .83 .86 .81 .80 .76 .73 .62
Aco2
KLA  ATP  ATP+KLA
AK029122 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732494K09 product:hypothetical protein, full insert sequence [AK029122] KLA 1.02 1.02 .99 .98 .97 1.04 .83
ATP .98 1.04 1.05 .95 .95 1.02 1.00
KLA/ATP .96 .95 1.00 1.04 1.06 1.03 .99
Aco2
KLA  ATP  ATP+KLA
NM_080633 aconitase 2, mitochondrial (Aco2), nuclear gene encoding mitochondrial protein, mRNA [NM_080633] KLA .93 .96 .97 .91 .97 .99 1.07
ATP 1.05 1.04 .98 .92 .90 .83 .99
KLA/ATP 1.01 1.06 .86 .89 .83 .93 .93
Acy1
KLA  ATP  ATP+KLA
NM_025371 aminoacylase 1 (Acy1), mRNA [NM_025371] KLA 1.09 1.23 1.15 1.16 1.14 1.11 .71
ATP 1.00 1.03 .98 1.13 1.30 1.30 1.13
KLA/ATP 1.22 1.18 .95 1.22 1.08 1.03 .71
Aldh18a1
KLA  ATP  ATP+KLA
NM_019698 aldehyde dehydrogenase 18 family, member A1 (Aldh18a1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA [NM_019698] KLA .71 .71 .63 .58 .72 1.04 1.22
ATP 1.25 1.41 .88 1.39 1.25 .73 1.37
KLA/ATP .86 .91 .43 .66 .47 .59 .59
Aldh7a1
KLA  ATP  ATP+KLA
NM_138600 aldehyde dehydrogenase family 7, member A1 (Aldh7a1), mRNA [NM_138600] KLA .98 1.03 1.08 1.12 1.08 .94 .99
ATP 1.01 1.03 1.00 1.03 .98 .82 .91
KLA/ATP 1.15 1.12 1.01 1.02 .90 .89 .83
Aldoa
KLA  ATP  ATP+KLA
NM_007438 aldolase 1, A isoform (Aldoa), mRNA [NM_007438] KLA .81 .83 .75 .81 .83 .80 1.22
ATP .97 .93 .78 .78 1.01 1.14 1.35
KLA/ATP .80 .86 .84 .70 .80 .81 1.12
Aldoart1
KLA  ATP  ATP+KLA
AK016845 adult male testis cDNA, RIKEN full-length enriched library, clone:4933417I20 product:ALDOLASE 1, A ISOFORM homolog [Mus musculus], full insert sequence [AK016845] KLA 1.01 1.01 1.03 .98 .95 .96 1.03
ATP 1.00 1.01 .98 .90 .99 1.03 .91
KLA/ATP .97 1.01 1.04 .99 1.07 1.00 .98
Aldob
KLA  ATP  ATP+KLA
NM_144903 aldolase 2, B isoform (Aldob), mRNA [NM_144903] KLA .99 1.01 1.02 1.02 1.02 1.03 1.04
ATP 1.02 1.02 1.00 1.05 1.02 1.02 1.01
KLA/ATP 1.01 1.04 1.00 1.03 1.03 1.02 .97
Aldoc
KLA  ATP  ATP+KLA
AK039267 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330009L16 product:aldolase 3, C isoform, full insert sequence [AK039267] KLA .84 .77 .75 .78 .51 .34 .14
ATP .86 .84 1.15 1.01 .85 .60 .33
KLA/ATP .71 .78 .94 .76 .60 .34 .14
Aldoc
KLA  ATP  ATP+KLA
NM_009657 aldolase 3, C isoform (Aldoc), mRNA [NM_009657] KLA .88 .94 .93 .76 .72 .46 .16
ATP 1.02 1.17 1.00 1.29 1.00 .62 .76
KLA/ATP .99 1.00 .82 1.04 .71 .46 .18
Arg1
KLA  ATP  ATP+KLA
NM_007482 arginase 1, liver (Arg1), mRNA [NM_007482] KLA .98 1.01 .97 .97 1.12 1.83 1.27
ATP .98 1.00 1.11 .94 .98 5.11 20.89
KLA/ATP .92 1.03 1.02 1.02 .99 3.54 18.22
Arg2
KLA  ATP  ATP+KLA
NM_009705 arginase type II (Arg2), mRNA [NM_009705] KLA 1.93 1.99 2.17 2.47 2.41 2.13 4.33
ATP 1.01 1.08 1.69 5.21 16.98 33.44 6.60
KLA/ATP 2.20 2.09 3.52 10.32 17.71 32.56 24.21
Asl
KLA  ATP  ATP+KLA
NM_133768 argininosuccinate lyase (Asl), mRNA [NM_133768] KLA .88 .92 .83 .75 .78 .83 1.05
ATP 1.00 1.09 .93 1.21 1.02 .85 1.41
KLA/ATP .89 .96 .74 1.01 .81 .85 1.55
Ass1
KLA  ATP  ATP+KLA
M31690 gb|Mouse argininosuccinate synthetase (Ass) mRNA, complete cds. [M31690] KLA 4.67 5.37 6.47 6.68 8.75 9.43 8.52
ATP 1.17 1.32 1.27 1.78 2.00 6.66 7.95
KLA/ATP 5.78 6.01 5.41 6.67 6.73 8.48 13.11
Ass1
KLA  ATP  ATP+KLA
NM_007494 argininosuccinate synthetase 1 (Ass1), mRNA [NM_007494] KLA 4.88 5.58 7.14 7.84 10.68 11.29 9.93
ATP 1.12 1.29 1.28 1.75 2.04 7.76 9.44
KLA/ATP 5.70 6.62 5.49 8.11 6.90 9.65 16.23
Bcat1
KLA  ATP  ATP+KLA
NM_001024468 branched chain aminotransferase 1, cytosolic (Bcat1), transcript variant 1, mRNA [NM_001024468] KLA 1.04 1.03 .98 1.04 .99 1.02 1.03
ATP 1.00 1.01 1.02 1.01 1.12 1.25 1.09
KLA/ATP .99 1.00 1.04 1.04 1.01 1.08 1.15
Bcat2
KLA  ATP  ATP+KLA
NM_009737 branched chain aminotransferase 2, mitochondrial (Bcat2), nuclear gene encoding mitochondrial protein, mRNA [NM_009737] KLA 1.06 1.05 1.08 .97 1.08 .96 1.61
ATP 1.07 1.42 .96 1.55 .87 .66 .96
KLA/ATP 1.27 1.29 .84 1.36 .81 .76 .92
Cbs
KLA  ATP  ATP+KLA
NM_144855 cystathionine beta-synthase (Cbs), transcript variant 1, mRNA [NM_144855] KLA .95 1.02 .94 .94 .99 .99 1.00
ATP 1.00 1.14 1.04 .85 .99 .94 .91
KLA/ATP 1.01 1.08 .97 1.02 .97 .88 .98
Cps1
KLA  ATP  ATP+KLA
AK028683 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732433M03 product:weakly similar to carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) large chain [Schizosaccharomyces pombe], full insert sequence. [A KLA .99 1.01 1.08 1.02 1.01 .96 1.05
ATP .96 1.00 .94 .97 .98 .98 1.05
KLA/ATP .97 1.09 1.04 .99 1.05 1.03 .96
Cps1
KLA  ATP  ATP+KLA
AK028683 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732433M03 product:weakly similar to carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) large chain [Schizosaccharomyces pombe], full insert sequence. [AK KLA 1.03 1.04 1.06 .96 1.08 1.08 1.03
ATP .99 .98 1.09 1.07 .97 1.02 1.09
KLA/ATP .98 1.00 .95 1.10 1.00 1.05 1.09
Cs
KLA  ATP  ATP+KLA
NM_026444 citrate synthase (Cs), nuclear gene encoding mitochondrial protein, mRNA [NM_026444] KLA 1.09 1.07 1.04 1.05 1.08 1.15 1.14
ATP .91 .93 1.02 .90 .90 1.08 1.38
KLA/ATP .99 1.04 1.09 .98 .98 .90 1.13
Csl
KLA  ATP  ATP+KLA
NM_027945 citrate synthase like (Csl), mRNA [NM_027945] KLA 1.41 1.32 1.35 1.51 1.61 1.39 1.58
ATP 1.17 1.15 .98 1.23 1.18 1.33 2.00
KLA/ATP 1.32 1.53 1.45 1.59 1.13 1.14 1.77
Cth
KLA  ATP  ATP+KLA
NM_145953 cystathionase (cystathionine gamma-lyase) (Cth), mRNA [NM_145953] KLA 1.95 1.88 2.04 1.99 1.70 1.19 1.05
ATP 1.05 1.03 1.17 1.26 1.76 2.05 1.00
KLA/ATP 1.79 2.03 2.06 1.83 1.66 1.53 .99
Eno1
KLA  ATP  ATP+KLA
NM_023119 enolase 1, alpha non-neuron (Eno1), mRNA [NM_023119] KLA .95 1.06 1.16 .78 1.04 .91 1.33
ATP 1.32 1.63 .81 1.78 1.08 1.07 1.65
KLA/ATP 1.50 1.43 .46 1.67 .61 1.02 1.97
Eno2
KLA  ATP  ATP+KLA
NM_013509 enolase 2, gamma neuronal (Eno2), mRNA [NM_013509] KLA .84 .85 .72 .81 1.23 1.24 2.08
ATP 1.07 1.13 1.14 3.24 4.11 1.61 2.43
KLA/ATP .93 .89 .85 1.68 3.37 1.66 2.69
Eno3
KLA  ATP  ATP+KLA
NM_007933 enolase 3, beta muscle (Eno3), mRNA [NM_007933] KLA .85 .86 .88 .84 .67 .70 1.00
ATP .92 .90 1.28 1.20 .96 .59 .68
KLA/ATP .82 .90 1.10 .99 .94 .52 .51
Gapdh
KLA  ATP  ATP+KLA
NM_008084 glyceraldehyde-3-phosphate dehydrogenase (Gapdh), mRNA [NM_008084] KLA .83 .87 .98 .70 .98 .82 1.34
ATP 1.24 1.33 .70 1.26 .95 .96 1.64
KLA/ATP 1.08 1.18 .50 .98 .61 .79 1.40
Glul
KLA  ATP  ATP+KLA
NM_008131 glutamate-ammonia ligase (glutamine synthetase) (Glul), mRNA [NM_008131] KLA .58 .54 .47 .41 .30 .31 .40
ATP .96 .99 1.46 2.55 2.16 2.88 1.34
KLA/ATP .57 .56 .83 1.52 1.27 1.20 .97
Glul
KLA  ATP  ATP+KLA
X16314 gb|M.musculus mRNA for glutamine synthetase. [X16314] KLA .86 .95 .79 .87 .78 .99 .83
ATP .95 1.03 1.09 1.27 1.14 1.37 1.00
KLA/ATP .88 .97 .89 1.12 1.01 1.19 .91
Got1
KLA  ATP  ATP+KLA
NM_010324 glutamate oxaloacetate transaminase 1, soluble (Got1), mRNA [NM_010324] KLA .68 .70 .66 .56 .50 .57 .99
ATP 1.01 1.24 1.55 1.59 1.47 1.03 1.68
KLA/ATP .68 .71 .66 .77 1.13 2.33 1.89
Got2
KLA  ATP  ATP+KLA
NM_010325 glutamate oxaloacetate transaminase 2, mitochondrial (Got2), nuclear gene encoding mitochondrial protein, mRNA [NM_010325] KLA .84 .86 .88 .75 .75 .63 .61
ATP 1.02 1.12 .98 1.15 .98 .67 .86
KLA/ATP .92 .89 .75 .89 .68 .70 .77
Gpt
KLA  ATP  ATP+KLA
NM_182805 glutamic pyruvic transaminase, soluble (Gpt), mRNA [NM_182805] KLA .82 .81 .80 .82 .78 .83 1.05
ATP 1.01 1.00 1.07 1.23 1.20 .77 1.01
KLA/ATP .85 .86 .93 1.01 1.32 .83 .97
Gpt2
KLA  ATP  ATP+KLA
NM_173866 glutamic pyruvate transaminase (alanine aminotransferase) 2 (Gpt2), mRNA [NM_173866] KLA .82 .87 .84 .69 .64 .80 .91
ATP .97 1.08 1.06 .95 1.33 2.66 1.89
KLA/ATP .81 .83 .67 .70 1.07 2.66 1.63
Idh1
KLA  ATP  ATP+KLA
NM_010497 isocitrate dehydrogenase 1 (NADP+), soluble (Idh1), transcript variant 2, mRNA [NM_010497] KLA .71 .74 .69 .70 .54 .45 .63
ATP 1.22 1.28 1.00 1.28 1.06 .62 .81
KLA/ATP .76 .81 .68 .88 .55 .47 .40
Idh2
KLA  ATP  ATP+KLA
NM_173011 isocitrate dehydrogenase 2 (NADP+), mitochondrial (Idh2), nuclear gene encoding mitochondrial protein, mRNA [NM_173011] KLA .83 .83 .88 .94 .66 .31 .38
ATP 1.04 1.09 1.14 1.48 1.26 .39 .49
KLA/ATP .90 .92 1.04 1.10 .82 .41 .20
Idh3a
KLA  ATP  ATP+KLA
NM_029573 isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a), nuclear gene encoding mitochondrial protein, mRNA [NM_029573] KLA .99 1.06 .85 .83 .67 .51 .73
ATP .95 1.07 1.12 1.22 .93 .46 .52
KLA/ATP .92 1.00 .91 1.12 .75 .42 .21
Idh3b
KLA  ATP  ATP+KLA
NM_130884 isocitrate dehydrogenase 3 (NAD+) beta (Idh3b), nuclear gene encoding mitochondrial protein, mRNA [NM_130884] KLA .89 .94 .94 .89 .97 1.00 1.12
ATP 1.01 1.07 .94 1.16 .94 .52 .68
KLA/ATP .92 .94 .78 1.05 .78 .73 .58
Idh3g
KLA  ATP  ATP+KLA
NM_008323 isocitrate dehydrogenase 3 (NAD+), gamma (Idh3g), nuclear gene encoding mitochondrial protein, mRNA [NM_008323] KLA .74 .69 .66 .68 .61 .55 .63
ATP .94 .91 1.06 1.09 .93 .66 .62
KLA/ATP .72 .74 .80 .80 .73 .56 .48
Mm.12773
1
KLA  ATP  ATP+KLA
142352287 Unknown KLA .97 .93 .99 .98 1.00 1.04 1.07
ATP .98 1.05 1.00 .89 .96 .99 1.13
KLA/ATP 1.00 1.02 1.06 .96 1.00 .91 1.22
Mm.17905
KLA  ATP  ATP+KLA
94536843 Unknown KLA 1.05 1.02 1.06 1.01 .76 .88 .91
ATP .91 .83 1.42 .91 .93 1.14 1.10
KLA/ATP 1.01 1.05 1.76 1.10 1.06 .89 .88
Mm.1845
KLA  ATP  ATP+KLA
142351600 Unknown KLA .93 .92 .89 .81 .76 .84 .65
ATP 1.01 .94 1.08 1.00 .77 1.95 1.13
KLA/ATP .91 .84 .85 .81 .59 .66 .77
Mm.45856
3
KLA  ATP  ATP+KLA
142351405 Unknown KLA .93 .96 .85 .74 .64 .68 .87
ATP 1.03 1.07 1.02 1.04 .94 1.01 1.14
KLA/ATP .98 .98 .75 .87 .68 1.02 1.15
Mm.79179
KLA  ATP  ATP+KLA
141803280 Unknown KLA .95 1.09 1.04 1.13 1.00 1.10 .98
ATP 1.02 1.17 1.04 1.18 1.06 1.02 1.01
KLA/ATP .98 1.00 1.02 1.01 .98 .93 .99
Mtr
KLA  ATP  ATP+KLA
AK037599 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130029B16 product:5-methyltetrahydrofolate-homocysteine methyltransferase, full insert sequence. [AK037599] KLA .89 .92 .81 .83 .73 .76 .98
ATP .98 1.11 .85 .93 .68 .72 1.12
KLA/ATP .92 .93 .71 .85 .66 .68 .77
Mtr
KLA  ATP  ATP+KLA
NM_001081128 5-methyltetrahydrofolate-homocysteine methyltransferase (Mtr), mRNA [NM_001081128] KLA .93 .91 .89 .77 .64 .58 .99
ATP 1.12 1.11 1.05 .87 .71 .69 1.59
KLA/ATP 1.02 .95 .96 .78 .54 .55 .92
Nags
KLA  ATP  ATP+KLA
NM_145829 N-acetylglutamate synthase (Nags), transcript variant 1, mRNA [NM_145829] KLA .99 .97 1.02 1.06 1.03 1.03 1.08
ATP .95 .98 1.07 1.12 1.17 1.38 1.26
KLA/ATP .97 1.05 1.10 1.42 1.31 1.52 1.27
Nags
KLA  ATP  ATP+KLA
NM_178053 N-acetylglutamate synthase (Nags), transcript variant 2, mRNA [NM_178053] KLA 1.01 .98 1.07 1.10 1.02 1.02 1.06
ATP 1.07 1.06 1.12 1.00 1.56 2.35 1.57
KLA/ATP .98 1.02 1.09 .94 1.32 1.66 1.29
Otc
KLA  ATP  ATP+KLA
BC024893 ornithine transcarbamylase, mRNA (cDNA clone MGC:28946 IMAGE:4196455), complete cds [BC024893] KLA 1.00 1.00 .92 1.03 .95 .98 1.00
ATP 1.05 .95 1.03 1.01 .96 1.05 .99
KLA/ATP .97 .99 .95 1.05 .92 1.00 1.01
Otc
KLA  ATP  ATP+KLA
NM_008769 ornithine transcarbamylase (Otc), mRNA [NM_008769] KLA 1.01 .98 .99 1.00 .99 .96 1.02
ATP 1.04 1.01 1.02 1.01 1.00 .94 .94
KLA/ATP .96 1.07 1.01 1.00 .95 1.00 .97
Pah
KLA  ATP  ATP+KLA
NM_008777 phenylalanine hydroxylase (Pah), mRNA [NM_008777] KLA .99 .93 1.06 .99 1.01 .99 .98
ATP 1.09 1.02 .99 .95 .97 .98 .99
KLA/ATP .97 .93 .97 .95 .95 1.00 .87
Pcx
KLA  ATP  ATP+KLA
NM_008797 pyruvate carboxylase (Pcx), nuclear gene encoding mitochondrial protein, mRNA [NM_008797] KLA 1.28 1.34 1.44 1.30 1.34 1.23 .91
ATP 1.11 1.09 1.19 1.29 1.19 1.49 1.16
KLA/ATP 1.34 1.41 1.63 1.53 1.39 1.05 1.15
Pfkl
KLA  ATP  ATP+KLA
NM_008826 phosphofructokinase, liver, B-type (Pfkl), mRNA [NM_008826] KLA 1.19 1.33 1.34 1.23 1.57 1.49 2.02
ATP 1.17 1.34 1.04 1.45 .92 1.53 .97
KLA/ATP 1.54 1.64 1.36 1.91 1.17 .89 1.61
Pfkm
KLA  ATP  ATP+KLA
NM_021514 phosphofructokinase, muscle (Pfkm), mRNA [NM_021514] KLA .73 .74 .70 .88 .80 .61 .55
ATP 1.09 1.05 1.01 1.06 .80 .50 .52
KLA/ATP .76 .83 .86 .75 .57 .57 .46
Pfkp
KLA  ATP  ATP+KLA
BC050264 gb|Mus musculus, clone IMAGE:4503748, mRNA [BC050264] KLA 4.07 3.58 3.25 2.41 1.31 .76 .81
ATP 1.26 1.26 2.77 2.20 4.63 2.57 4.92
KLA/ATP 4.81 4.66 8.95 3.50 3.96 1.60 .91
Pfkp
KLA  ATP  ATP+KLA
NM_019703 phosphofructokinase, platelet (Pfkp), mRNA [NM_019703] KLA 1.94 1.99 2.15 2.05 1.90 1.20 .85
ATP 1.08 1.05 1.18 1.20 1.40 1.38 .93
KLA/ATP 1.94 2.12 2.35 2.26 1.91 1.36 .88
Pgam1
KLA  ATP  ATP+KLA
NM_023418 phosphoglycerate mutase 1 (Pgam1), mRNA [NM_023418] KLA .71 .69 .75 .85 .89 .84 1.30
ATP 1.02 1.10 1.00 .99 1.47 2.02 1.36
KLA/ATP .83 .83 .74 .76 1.24 1.73 1.11
Pgam2
KLA  ATP  ATP+KLA
NM_018870 phosphoglycerate mutase 2 (Pgam2), mRNA [NM_018870] KLA .99 1.05 1.11 1.10 1.10 1.14 1.30
ATP 1.09 1.08 1.17 1.17 1.31 1.63 1.18
KLA/ATP 1.07 1.08 1.06 1.09 1.27 1.42 1.13
Pgk1
KLA  ATP  ATP+KLA
NM_008828 phosphoglycerate kinase 1 (Pgk1), mRNA [NM_008828] KLA .98 1.04 1.04 .99 1.01 1.03 1.16
ATP 1.00 .94 .70 .64 .79 1.34 1.54
KLA/ATP 1.02 .96 .80 .72 .70 .90 1.24
Pgk2
KLA  ATP  ATP+KLA
NM_031190 phosphoglycerate kinase 2 (Pgk2), mRNA [NM_031190] KLA .96 .97 .96 1.08 .96 1.01 .98
ATP .98 .98 1.07 1.03 1.03 1.00 1.00
KLA/ATP 1.01 1.04 1.02 .95 1.05 .98 1.04
Phgdh
KLA  ATP  ATP+KLA
NM_016966 3-phosphoglycerate dehydrogenase (Phgdh), mRNA [NM_016966] KLA 1.06 1.11 .97 .89 .82 .80 .91
ATP 1.02 1.03 1.17 1.33 3.31 3.86 .74
KLA/ATP 1.07 1.06 1.15 1.38 1.78 1.84 .40
Pklr
KLA  ATP  ATP+KLA
NM_013631 pyruvate kinase liver and red blood cell (Pklr), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA [NM_013631] KLA 1.06 1.01 1.12 1.00 .98 1.01 1.07
ATP .98 .94 1.05 1.06 1.01 1.06 1.10
KLA/ATP .97 1.00 1.04 .95 .89 1.05 .97
Pkm2
KLA  ATP  ATP+KLA
D38379 mRNA for pyruvate kinase M, complete cds. [D38379] KLA .80 .83 .94 .67 .95 .95 1.42
ATP 1.22 1.30 .83 1.14 .99 1.23 2.53
KLA/ATP .99 1.03 .61 .83 .70 1.16 2.54
Pkm2
KLA  ATP  ATP+KLA
NM_011099 pyruvate kinase, muscle (Pkm2), mRNA [NM_011099] KLA .84 .89 .95 .72 .92 1.03 1.34
ATP 1.05 1.23 .83 1.13 .96 1.20 2.14
KLA/ATP .98 .97 .64 .89 .73 1.20 2.32
Prps1
KLA  ATP  ATP+KLA
NM_021463 phosphoribosyl pyrophosphate synthetase 1 (Prps1), mRNA [NM_021463] KLA .82 .83 .85 .70 .56 .42 .52
ATP 1.00 1.03 1.20 1.21 1.08 .67 .54
KLA/ATP .85 .86 .90 .86 .68 .52 .42
Prps1l1
KLA  ATP  ATP+KLA
NM_029294 phosphoribosyl pyrophosphate synthetase 1-like 1 (Prps1l1), mRNA [NM_029294] KLA 1.05 .97 .99 1.03 1.04 1.00 1.04
ATP .99 .96 1.04 1.05 1.05 .99 1.07
KLA/ATP .99 1.03 1.07 1.00 1.01 1.01 1.09
Prps2
KLA  ATP  ATP+KLA
NM_026662 phosphoribosyl pyrophosphate synthetase 2 (Prps2), mRNA [NM_026662] KLA .85 .85 .88 .76 .60 .45 .43
ATP 1.00 1.13 1.18 1.19 .79 .35 .37
KLA/ATP .85 .93 .88 .83 .62 .38 .24
Psat1
KLA  ATP  ATP+KLA
NM_177420 phosphoserine aminotransferase 1 (Psat1), mRNA [NM_177420] KLA 1.02 1.21 1.24 1.27 1.64 1.59 .38
ATP 1.02 1.01 1.04 1.17 1.27 1.09 .43
KLA/ATP 1.16 1.11 1.04 1.37 1.04 .70 .24
Psph
KLA  ATP  ATP+KLA
NM_133900 phosphoserine phosphatase (Psph), mRNA [NM_133900] KLA .94 .88 .76 .88 .65 .87 .75
ATP .77 .61 .53 .35 1.23 1.85 .73
KLA/ATP .71 .64 .54 .31 .46 .78 .61
Pycr2
KLA  ATP  ATP+KLA
NM_133705 pyrroline-5-carboxylate reductase family, member 2 (Pycr2), mRNA [NM_133705] KLA .59 .56 .56 .66 .62 .65 .80
ATP .86 .74 .49 .43 .33 .56 .69
KLA/ATP .53 .50 .41 .30 .29 .54 .52
Pycrl
KLA  ATP  ATP+KLA
AK004291 18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1110058B13 product:pyrroline-5-carboxylate reductase-like, full insert sequence. [AK004291] KLA .50 .57 .50 .50 .54 .66 .74
ATP .98 .99 .97 1.09 .76 .48 .60
KLA/ATP .58 .55 .48 .54 .59 .53 .44
Pycrl
KLA  ATP  ATP+KLA
NM_025412 pyrroline-5-carboxylate reductase-like (Pycrl), mRNA [NM_025412] KLA .66 .69 .67 .64 .64 .78 .89
ATP .99 1.01 1.03 1.10 .78 .61 .69
KLA/ATP .66 .69 .70 .69 .68 .63 .56
Rpe
KLA  ATP  ATP+KLA
NM_025683 ribulose-5-phosphate-3-epimerase (Rpe), mRNA [NM_025683] KLA 2.06 2.10 2.39 2.33 2.29 2.01 1.45
ATP 1.01 1.14 1.25 1.29 .90 .80 .89
KLA/ATP 1.87 2.38 2.22 2.33 1.57 1.08 1.10
Sds
KLA  ATP  ATP+KLA
NM_145565 serine dehydratase (Sds), mRNA [NM_145565] KLA 1.04 1.04 1.02 1.03 1.07 1.05 .77
ATP .93 .97 .91 .94 1.00 .94 1.00
KLA/ATP .93 .95 1.05 .96 .98 .96 1.05
Shmt1
KLA  ATP  ATP+KLA
NM_009171 serine hydroxymethyltransferase 1 (soluble) (Shmt1), mRNA [NM_009171] KLA .85 .89 .82 .83 .82 .88 .83
ATP .93 .81 .85 .82 .85 .86 .72
KLA/ATP .81 .83 .91 .86 .85 .86 .72
Shmt2
KLA  ATP  ATP+KLA
NM_028230 serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2), nuclear gene encoding mitochondrial protein, mRNA [NM_028230] KLA .82 .90 .78 .63 .51 .39 .63
ATP 1.04 1.21 .97 1.44 1.32 .85 .64
KLA/ATP .94 .92 .62 1.01 .59 .49 .32
Taldo1
KLA  ATP  ATP+KLA
NM_011528 transaldolase 1 (Taldo1), mRNA [NM_011528] KLA .82 .79 .79 .76 .63 .56 .56
ATP .93 .96 1.02 .91 1.13 1.91 2.17
KLA/ATP .77 .80 .86 .75 .94 1.33 1.43
Tat
KLA  ATP  ATP+KLA
NM_146214 tyrosine aminotransferase (Tat), nuclear gene encoding mitochondrial protein, mRNA [NM_146214] KLA 1.13 1.09 1.19 1.17 1.14 1.19 1.10
ATP .97 1.08 1.12 1.25 1.02 1.16 1.18
KLA/ATP 1.16 1.21 1.27 1.23 1.22 1.11 1.08
Tha1
KLA  ATP  ATP+KLA
NM_027919 threonine aldolase 1 (Tha1), mRNA [NM_027919] KLA 3.92 4.62 4.23 4.99 4.59 2.42 2.04
ATP .98 .92 .78 .74 .78 1.21 1.03
KLA/ATP 4.35 4.64 3.33 2.80 1.63 1.41 1.50
Tkt
KLA  ATP  ATP+KLA
NM_009388 transketolase (Tkt), mRNA [NM_009388] KLA .97 1.00 .97 1.00 .90 .86 .90
ATP .99 1.00 1.03 .97 .89 .83 .58
KLA/ATP 1.01 1.00 .97 .91 .80 .76 .51
Tktl1
KLA  ATP  ATP+KLA
NM_031379 transketolase-like 1 (Tktl1), mRNA [NM_031379] KLA 1.07 1.01 .98 1.03 .97 .99 .93
ATP 1.02 1.02 .98 .91 .99 1.06 .95
KLA/ATP .96 .98 .96 .99 1.05 .99 1.00
Tktl2
KLA  ATP  ATP+KLA
AK029871 adult male testis cDNA, RIKEN full-length enriched library, clone:4931419A11 product:TRANSKETOLASE (FRAGMENT) homolog [Mus musculus], full insert sequence [AK029871] KLA 1.09 1.03 1.10 .98 1.03 .96 .94
ATP .96 1.05 .99 1.00 .94 1.02 1.02
KLA/ATP .95 .92 1.15 1.06 .99 .93 .98
Tktl2
KLA  ATP  ATP+KLA
NM_028927 transketolase-like 2 (Tktl2), mRNA [NM_028927] KLA 1.02 .98 .98 .98 1.01 .97 .98
ATP 1.06 1.01 1.01 .99 .93 1.01 1.06
KLA/ATP 1.02 1.03 .98 .99 .96 1.00 .99
Tpi1
KLA  ATP  ATP+KLA
NM_009415 triosephosphate isomerase 1 (Tpi1), mRNA [NM_009415] KLA .70 .79 .73 .61 .66 .67 1.32
ATP 1.04 1.22 .90 1.30 .95 .86 1.24
KLA/ATP .84 .82 .55 .90 .66 .74 1.54