Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Apoptosis (mmu04210)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
1500003O
03Rik
KLA  ATP  ATP+KLA
 NM_019769 RIKEN cDNA 1500003O03 gene (1500003O03Rik), mRNA [NM_019769] KLA .92 .89 .89 .86 .85 .92 1.08
ATP 1.01 1.16 1.16 1.53 1.70 3.33 2.09
KLA/ATP .89 .97 .93 1.17 1.19 2.86 2.57
2010110P
09Rik
KLA  ATP  ATP+KLA
 NM_027363 RIKEN cDNA 2010110P09 gene (2010110P09Rik), mRNA [NM_027363] KLA .99 .98 1.02 .99 .94 1.01 1.01
ATP 1.04 1.05 .97 1.05 .95 .98 .95
KLA/ATP .93 1.00 1.02 .97 1.01 .96 .97
AK036998
KLA  ATP  ATP+KLA
 AK036998 adult female vagina cDNA, RIKEN full-length enriched library, clone:9930034M05 product:unclassifiable, full insert sequence. [AK036998] KLA 1.43 1.09 .89 .79 .96 .97 .71
ATP 1.04 1.04 .71 .64 .90 .82 .82
KLA/ATP 1.34 1.23 1.01 .89 1.10 .82 .75
Aifm1
KLA  ATP  ATP+KLA
 NM_012019 apoptosis-inducing factor, mitochondrion-associated 1 (Aifm1), nuclear gene encoding mitochondrial protein, mRNA [NM_012019] KLA .85 .82 .80 .72 .63 .66 .74
ATP 1.04 1.00 1.18 1.12 1.55 2.04 .89
KLA/ATP .82 .86 .94 .81 .86 1.09 .63
Akt1
KLA  ATP  ATP+KLA
 NM_009652 thymoma viral proto-oncogene 1 (Akt1), mRNA [NM_009652] KLA .80 .80 .75 .75 .71 .70 .82
ATP 1.00 1.02 .76 .85 .76 .68 .84
KLA/ATP .82 .80 .64 .68 .67 .61 .72
Akt2
KLA  ATP  ATP+KLA
 NM_007434 thymoma viral proto-oncogene 2 (Akt2), transcript variant 2, mRNA [NM_007434] KLA 1.45 1.49 1.81 1.61 1.83 1.17 .92
ATP 1.12 1.12 1.00 1.28 1.20 .94 1.06
KLA/ATP 1.48 1.70 1.69 1.58 1.57 1.32 1.27
Akt3
KLA  ATP  ATP+KLA
 NM_011785 thymoma viral proto-oncogene 3 (Akt3), mRNA [NM_011785] KLA 3.42 3.45 5.31 5.16 4.65 3.80 2.12
ATP 1.12 1.22 1.10 1.37 1.02 1.11 1.56
KLA/ATP 3.72 4.17 4.62 4.64 2.74 2.05 3.82
Apaf1
KLA  ATP  ATP+KLA
 NM_001042558 apoptotic peptidase activating factor 1 (Apaf1), transcript variant 1, mRNA [NM_001042558] KLA 2.92 2.81 3.22 2.74 2.42 1.74 1.40
ATP 1.05 .99 .87 .81 1.61 2.03 1.46
KLA/ATP 2.90 2.78 2.01 1.69 1.56 2.77 2.73
Atm
KLA  ATP  ATP+KLA
 NM_007499 ataxia telangiectasia mutated homolog (human) (Atm), mRNA [NM_007499] KLA 1.86 1.97 2.17 1.67 1.20 .86 .79
ATP 1.09 1.17 1.01 .97 .61 .63 .69
KLA/ATP 2.11 2.24 1.55 1.46 .85 .75 .59
Bad
KLA  ATP  ATP+KLA
 AK029400 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4833429M11 product:Bcl-associated death promoter, full insert sequence. [AK029400] KLA 1.15 1.22 1.26 1.31 1.40 1.67 1.59
ATP .95 1.06 1.12 1.06 .78 .89 1.27
KLA/ATP 1.25 1.39 1.33 1.29 1.11 .91 1.38
Bax
KLA  ATP  ATP+KLA
 NM_007527 Bcl2-associated X protein (Bax), mRNA [NM_007527] KLA 1.08 1.14 1.10 1.14 1.17 1.06 .92
ATP 1.06 1.05 1.02 1.25 1.26 .90 .86
KLA/ATP 1.11 1.19 1.30 1.34 1.34 .87 .71
Bcl2
KLA  ATP  ATP+KLA
 NM_009741 B-cell leukemia/lymphoma 2 (Bcl2), transcript variant 1, mRNA [NM_009741] KLA .30 .26 .25 .25 .34 .38 .26
ATP .97 .89 1.50 1.04 .99 .29 .52
KLA/ATP .28 .26 .40 .33 .62 .29 .12
Bcl2
KLA  ATP  ATP+KLA
 NM_177410 B-cell leukemia/lymphoma 2 (Bcl2), transcript variant 2, mRNA [NM_177410] KLA .33 .33 .37 .42 .49 .46 .39
ATP 1.07 1.12 1.22 1.56 1.00 .38 .76
KLA/ATP .35 .34 .54 .89 .76 .36 .23
Bcl2l1
KLA  ATP  ATP+KLA
 NM_009743 Bcl2-like 1 (Bcl2l1), nuclear gene encoding mitochondrial protein, mRNA [NM_009743] KLA .99 1.02 1.10 1.16 1.27 .97 1.05
ATP 1.18 1.42 .81 1.26 1.51 .71 1.67
KLA/ATP 1.21 1.30 .66 1.15 1.31 1.17 1.59
Bid
KLA  ATP  ATP+KLA
 NM_007544 BH3 interacting domain death agonist (Bid), mRNA [NM_007544] KLA 1.03 1.08 1.09 1.14 1.01 .99 .68
ATP 1.06 1.11 .97 .89 1.04 1.17 1.08
KLA/ATP .88 1.09 .92 1.06 1.16 1.28 1.56
Birc2
KLA  ATP  ATP+KLA
 NM_007465 baculoviral IAP repeat-containing 2 (Birc2), mRNA [NM_007465] KLA 4.63 4.59 3.77 2.79 2.32 2.07 1.84
ATP .95 .88 .84 .92 .76 1.34 1.28
KLA/ATP 4.70 4.93 4.13 2.60 1.34 1.60 2.31
Birc3
KLA  ATP  ATP+KLA
 BC011338 baculoviral IAP repeat-containing 3, mRNA (cDNA clone MGC:18386 IMAGE:3661563), complete cds [BC011338] KLA 5.48 5.46 4.94 4.16 4.91 3.36 3.74
ATP 1.05 1.08 4.21 4.28 2.59 2.55 1.57
KLA/ATP 6.78 8.91 11.01 4.87 2.28 2.12 3.66
Birc3
KLA  ATP  ATP+KLA
 NM_007464 baculoviral IAP repeat-containing 3 (Birc3), mRNA [NM_007464] KLA 17.83 15.88 13.48 11.14 11.79 6.90 6.10
ATP 1.14 1.16 1.70 4.07 5.00 6.33 2.41
KLA/ATP 14.77 16.44 19.09 13.91 8.27 6.22 7.73
Birc7
KLA  ATP  ATP+KLA
 AK053463 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130019N06 product:weakly similar to BA261N11.1.3 (BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 (LIVIN), ISOFORM 3) (FRAGMENT) [Homo sapiens], full insert sequence [AK05 KLA 1.02 1.02 .93 1.01 .91 1.27 1.07
ATP 1.02 1.03 .99 .93 .96 .98 1.01
KLA/ATP 1.00 1.04 .97 .94 .91 .93 .92
Capn1
KLA  ATP  ATP+KLA
 NM_007600 calpain 1 (Capn1), transcript variant 1, mRNA [NM_007600] KLA 1.28 1.27 1.46 1.23 1.37 1.27 .99
ATP 1.07 1.24 .99 1.33 .98 .89 1.21
KLA/ATP 1.46 1.49 1.09 1.57 1.03 1.18 1.28
Capn2
KLA  ATP  ATP+KLA
 NM_009794 calpain 2 (Capn2), mRNA [NM_009794] KLA .63 .65 .70 .57 .60 .61 .58
ATP 1.03 1.21 .78 .98 .82 .59 1.19
KLA/ATP .80 .71 .37 .54 .45 .46 1.05
Casp12
KLA  ATP  ATP+KLA
 NM_009808 caspase 12 (Casp12), mRNA [NM_009808] KLA 6.56 6.38 7.54 6.85 5.36 2.61 1.46
ATP .99 .98 1.17 1.56 1.32 1.40 1.13
KLA/ATP 6.27 6.52 5.79 5.68 3.74 2.21 1.78
Casp3
KLA  ATP  ATP+KLA
 NM_009810 caspase 3 (Casp3), mRNA [NM_009810] KLA 1.66 1.94 2.47 2.61 3.01 2.96 1.44
ATP .90 .99 1.17 1.30 1.01 1.17 .86
KLA/ATP 1.55 1.87 2.40 2.35 2.27 2.84 2.52
Casp3
KLA  ATP  ATP+KLA
 U49929 ICE-like cysteine protease (Lice) mRNA, complete cds. [U49929] KLA 1.71 1.87 2.69 3.11 3.64 3.42 1.52
ATP 1.04 1.07 1.16 1.34 .98 1.27 .86
KLA/ATP 1.80 1.96 2.46 2.91 2.50 3.24 3.10
Casp6
KLA  ATP  ATP+KLA
 NM_009811 caspase 6 (Casp6), mRNA [NM_009811] KLA .82 .78 .80 .80 .67 .60 .61
ATP .95 .92 1.18 1.08 .84 1.60 .72
KLA/ATP .76 .73 .90 .80 .72 1.30 .80
Casp7
KLA  ATP  ATP+KLA
 NM_007611 caspase 7 (Casp7), mRNA [NM_007611] KLA 3.50 3.60 4.52 5.05 5.20 2.96 1.27
ATP 1.03 1.14 1.20 1.27 .82 .77 .84
KLA/ATP 3.32 3.86 3.98 5.27 3.49 2.55 2.30
Casp8
KLA  ATP  ATP+KLA
 NM_009812 caspase 8 (Casp8), transcript variant 1, mRNA [NM_009812] KLA 2.41 2.53 3.20 3.26 2.75 2.78 1.57
ATP .91 .96 .66 .67 .54 1.53 1.52
KLA/ATP 2.47 2.52 2.08 2.41 1.41 2.50 2.77
Casp9
KLA  ATP  ATP+KLA
 NM_015733 caspase 9 (Casp9), mRNA [NM_015733] KLA .31 .31 .40 .66 .89 1.19 .91
ATP .88 .77 .91 .59 .43 .75 .93
KLA/ATP .26 .26 .30 .28 .80 1.06 .97
Cflar
KLA  ATP  ATP+KLA
 NM_009805 CASP8 and FADD-like apoptosis regulator (Cflar), transcript variant 2, mRNA [NM_009805] KLA 18.63 20.03 20.30 17.44 17.99 11.88 7.25
ATP .95 1.03 1.20 2.78 4.04 3.45 3.30
KLA/ATP 19.31 19.09 11.65 13.57 7.62 6.20 11.21
Cflar
KLA  ATP  ATP+KLA
 NM_207653 CASP8 and FADD-like apoptosis regulator (Cflar), transcript variant 1, mRNA [NM_207653] KLA 12.32 12.86 11.83 11.79 12.14 8.52 5.42
ATP .92 .92 1.63 4.97 7.95 5.18 2.39
KLA/ATP 12.27 13.57 13.15 12.79 10.27 7.71 8.32
Cflar
KLA  ATP  ATP+KLA
 Y14041 mRNA for CASH alpha protein. [Y14041] KLA 14.31 13.82 13.05 13.06 14.36 9.02 5.92
ATP 1.18 1.15 1.66 6.44 8.99 5.20 2.73
KLA/ATP 15.53 17.07 14.00 17.10 10.76 8.02 9.97
Chuk
KLA  ATP  ATP+KLA
 NM_007700 conserved helix-loop-helix ubiquitous kinase (Chuk), mRNA [NM_007700] KLA 1.32 1.42 1.41 1.17 1.32 1.22 1.40
ATP 1.22 1.30 1.18 .97 1.02 1.00 1.37
KLA/ATP 1.56 1.61 1.21 1.09 .83 .84 1.17
Csf2rb
KLA  ATP  ATP+KLA
 NM_007780 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb), mRNA [NM_007780] KLA 1.35 1.52 1.85 1.87 2.61 2.52 2.54
ATP 1.09 1.15 1.08 1.83 6.59 6.78 7.07
KLA/ATP 1.55 1.66 1.38 2.67 6.21 6.94 6.57
Csf2rb2
KLA  ATP  ATP+KLA
 NM_007781 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) (Csf2rb2), mRNA [NM_007781] KLA .78 .77 .81 1.04 1.45 1.45 1.91
ATP 1.12 1.03 .89 1.11 6.65 7.45 8.58
KLA/ATP .87 .87 .84 1.09 4.89 7.15 8.83
Cycs
KLA  ATP  ATP+KLA
 NM_007808 cytochrome c, somatic (Cycs), nuclear gene encoding mitochondrial protein, mRNA [NM_007808] KLA 2.20 2.21 2.35 2.69 2.62 3.22 2.14
ATP .87 .89 1.31 1.05 1.06 1.20 1.26
KLA/ATP 1.88 2.04 2.86 2.26 2.57 2.45 2.03
Cyct
KLA  ATP  ATP+KLA
 NM_009989 cytochrome c, testis (Cyct), mRNA [NM_009989] KLA .93 1.01 1.00 .99 1.02 1.03 .96
ATP 1.01 .91 1.01 .99 .98 .95 .95
KLA/ATP 1.10 .96 .89 .89 1.10 1.05 .97
Dffa
KLA  ATP  ATP+KLA
 NM_001025296 DNA fragmentation factor, alpha subunit (Dffa), transcript variant 1, mRNA [NM_001025296] KLA .96 .94 .93 .86 1.01 .91 .92
ATP 1.11 1.16 1.09 1.09 .73 .64 .83
KLA/ATP 1.02 1.02 .97 1.04 .67 .61 .69
Dffa
KLA  ATP  ATP+KLA
 NM_010044 DNA fragmentation factor, alpha subunit (Dffa), transcript variant 2, mRNA [NM_010044] KLA .85 .92 1.01 .94 .98 .88 .91
ATP 1.07 1.08 1.11 1.08 .80 .65 1.04
KLA/ATP .99 1.00 1.03 1.00 .74 .69 .71
Dffb
KLA  ATP  ATP+KLA
 NM_007859 DNA fragmentation factor, beta subunit (Dffb), mRNA [NM_007859] KLA .94 .81 .86 .86 .92 .90 .82
ATP 1.01 .90 .64 .60 .87 1.11 .93
KLA/ATP .84 .75 .71 .72 .90 .98 .80
Endog
KLA  ATP  ATP+KLA
 NM_007931 endonuclease G (Endog), nuclear gene encoding mitochondrial protein, mRNA [NM_007931] KLA .78 .76 .68 .66 .68 .77 1.12
ATP .99 1.08 .99 1.06 .71 .98 1.11
KLA/ATP .73 .74 .62 .69 .58 .93 .67
Fadd
KLA  ATP  ATP+KLA
 NM_010175 Fas (TNFRSF6)-associated via death domain (Fadd), mRNA [NM_010175] KLA .54 .54 .59 .64 .80 .97 1.16
ATP 1.05 1.09 1.03 1.65 1.18 .78 1.61
KLA/ATP .56 .56 .53 .78 .78 .82 1.34
Fas
KLA  ATP  ATP+KLA
 AK086933 0 day neonate lung cDNA, RIKEN full-length enriched library, clone:E030012O08 product:tumor necrosis factor receptor superfamily, member 6, full insert sequence. [AK086933] KLA 6.31 6.56 6.33 6.70 4.93 3.74 2.48
ATP .95 1.04 1.33 1.55 1.85 6.00 2.77
KLA/ATP 5.67 7.16 7.71 7.73 6.02 5.79 7.85
Fas
KLA  ATP  ATP+KLA
 NM_007987 Fas (TNF receptor superfamily member 6) (Fas), mRNA [NM_007987] KLA 17.08 17.45 19.08 17.38 13.33 6.78 4.46
ATP .98 .96 1.64 3.05 5.58 12.91 1.89
KLA/ATP 16.57 17.25 26.06 23.57 22.03 16.74 13.29
Fasl
KLA  ATP  ATP+KLA
 NM_010177 Fas ligand (TNF superfamily, member 6) (Fasl), mRNA [NM_010177] KLA 1.03 1.01 1.03 1.02 1.01 1.01 1.00
ATP 1.00 .99 1.04 1.21 1.18 1.20 1.01
KLA/ATP 1.00 1.02 1.07 1.16 1.18 1.23 1.00
Ikbkb
KLA  ATP  ATP+KLA
 NM_010546 inhibitor of kappaB kinase beta (Ikbkb), mRNA [NM_010546] KLA 1.88 2.10 2.14 1.83 1.73 1.31 1.19
ATP .81 .74 .55 .49 .59 1.05 .96
KLA/ATP 1.86 1.73 1.39 1.12 .89 1.17 1.24
Ikbkg
KLA  ATP  ATP+KLA
 AK042138 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630062P04 product:unclassifiable, full insert sequence. [AK042138] KLA .92 .87 .78 .78 .87 .88 .62
ATP .84 .71 .80 .50 1.15 2.33 .61
KLA/ATP .72 .69 .74 .48 1.06 1.97 .68
Ikbkg
KLA  ATP  ATP+KLA
 NM_010547 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 1, mRNA [NM_010547] KLA 1.51 1.63 1.74 1.83 1.83 1.73 1.72
ATP .80 .79 .82 .75 .66 2.58 2.37
KLA/ATP 1.43 1.42 1.17 1.04 .71 1.54 3.17
Ikbkg
KLA  ATP  ATP+KLA
 NM_178590 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 2, mRNA [NM_178590] KLA .84 .93 .86 .91 1.03 .89 .88
ATP 1.03 .98 .68 .56 .51 .93 .68
KLA/ATP .89 .81 .55 .52 .41 .67 .65
Il1a
KLA  ATP  ATP+KLA
 NM_010554 interleukin 1 alpha (Il1a), mRNA [NM_010554] KLA 32.45 35.22 31.30 20.95 28.57 18.36 19.02
ATP 1.04 1.02 2.21 5.46 11.06 32.07 3.40
KLA/ATP 32.02 41.20 35.12 46.91 28.76 42.72 57.80
Il1b
KLA  ATP  ATP+KLA
 NM_008361 interleukin 1 beta (Il1b), mRNA [NM_008361] KLA 149.78 133.59 100.91 116.58 86.48 89.37 64.72
ATP 3.49 13.96 61.44 70.91 82.12 162.79 28.18
KLA/ATP 130.32 139.00 219.12 148.17 165.44 172.57 146.98
Il1r1
KLA  ATP  ATP+KLA
 NM_008362 interleukin 1 receptor, type I (Il1r1), transcript variant 1, mRNA [NM_008362] KLA 1.20 1.08 1.22 1.52 2.19 2.32 1.61
ATP 1.10 .96 1.18 1.56 8.14 9.56 7.54
KLA/ATP 1.22 1.13 1.37 1.85 4.54 6.85 8.96
Il1rap
KLA  ATP  ATP+KLA
 AK032620 adult male olfactory brain cDNA, RIKEN full-length enriched library, clone:6430709H04 product:unclassifiable, full insert sequence [AK032620] KLA 1.05 .98 1.07 .95 .98 .95 .92
ATP .95 .98 1.05 1.01 .94 1.01 1.02
KLA/ATP .96 1.07 1.07 1.10 .99 1.03 1.01
Il1rap
KLA  ATP  ATP+KLA
 AK045686 adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230304B05 product:interleukin 1 receptor accessory protein, full insert sequence [AK045686] KLA 2.25 2.43 2.55 2.32 2.32 1.35 .81
ATP 1.13 1.31 1.25 1.28 1.04 1.28 .75
KLA/ATP 2.49 2.48 1.87 2.62 1.83 1.50 .77
Il1rap
KLA  ATP  ATP+KLA
 NM_008364 interleukin 1 receptor accessory protein (Il1rap), transcript variant 1, mRNA [NM_008364] KLA 1.11 1.16 1.17 1.15 1.11 .97 .97
ATP 1.02 1.12 1.07 1.03 1.01 .98 .84
KLA/ATP 1.20 1.19 1.07 1.10 .98 1.06 .89
Il1rap
KLA  ATP  ATP+KLA
 NM_134103 interleukin 1 receptor accessory protein (Il1rap), transcript variant 2, mRNA [NM_134103] KLA 1.42 1.42 1.46 1.39 1.40 1.14 .90
ATP 1.10 1.16 1.22 1.04 .98 .81 .79
KLA/ATP 1.45 1.53 1.33 1.33 1.08 .98 .75
Il3
KLA  ATP  ATP+KLA
 NM_010556 interleukin 3 (Il3), mRNA [NM_010556] KLA 1.05 .94 1.01 .99 1.03 1.07 .95
ATP .95 1.03 1.03 .98 .98 .97 .96
KLA/ATP 1.02 1.03 1.02 .94 .97 1.02 1.04
Il3ra
KLA  ATP  ATP+KLA
 NM_008369 interleukin 3 receptor, alpha chain (Il3ra), mRNA [NM_008369] KLA 1.23 1.35 1.52 1.31 1.38 1.42 1.35
ATP 1.04 1.20 1.11 1.42 1.18 .94 .77
KLA/ATP 1.33 1.45 1.45 1.69 1.25 1.22 1.32
Irak1
KLA  ATP  ATP+KLA
 NM_008363 interleukin-1 receptor-associated kinase 1 (Irak1), mRNA [NM_008363] KLA .67 .67 .64 .56 .58 .58 .84
ATP 1.02 1.10 .94 1.14 .81 .54 .87
KLA/ATP .72 .72 .57 .67 .51 .43 .62
Irak2
KLA  ATP  ATP+KLA
 NM_172161 interleukin-1 receptor-associated kinase 2 (Irak2), transcript variant 1, mRNA [NM_172161] KLA 8.24 8.89 7.70 6.43 6.61 4.53 3.48
ATP 1.06 1.22 1.26 2.10 4.99 4.55 2.69
KLA/ATP 8.32 9.13 7.57 7.95 5.01 6.84 8.36
Irak3
KLA  ATP  ATP+KLA
 NM_028679 interleukin-1 receptor-associated kinase 3 (Irak3), mRNA [NM_028679] KLA 2.04 2.22 2.80 3.81 6.02 4.81 6.76
ATP 1.13 1.14 1.02 1.26 .97 2.51 1.31
KLA/ATP 2.24 2.35 2.06 2.58 1.43 1.55 4.63
Irak4
KLA  ATP  ATP+KLA
 NM_029926 interleukin-1 receptor-associated kinase 4 (Irak4), mRNA [NM_029926] KLA .82 .86 .78 .82 .95 1.21 1.22
ATP 1.02 1.18 .95 1.10 .79 .85 .82
KLA/ATP .86 .89 .77 .90 .78 .96 .88
Map3k14
KLA  ATP  ATP+KLA
 NM_016896 mitogen-activated protein kinase kinase kinase 14 (Map3k14), mRNA [NM_016896] KLA .32 .30 .40 .52 1.08 1.14 .94
ATP 1.18 1.24 1.13 .85 .82 .84 .99
KLA/ATP .33 .30 .34 .50 1.02 .84 1.43
Mm.15898
1
KLA  ATP  ATP+KLA
 142388182 Unknown KLA .25 .22 .31 .50 .85 1.11 .83
ATP 1.02 .94 1.31 .76 .73 .96 .92
KLA/ATP .24 .22 .34 .38 1.16 .96 1.23
Mm.18787
9
KLA  ATP  ATP+KLA
 149250519 Unknown KLA .98 .98 1.02 1.05 1.01 1.10 1.02
ATP 1.03 1.00 .98 1.02 1.02 1.04 .99
KLA/ATP .99 1.07 1.04 1.02 .94 .97 .93
Mm.21312
8
KLA  ATP  ATP+KLA
 141801344 Unknown KLA .96 .95 .83 .77 .52 .99 1.32
ATP .80 .82 1.09 .80 .83 1.19 1.46
KLA/ATP .78 .92 .98 .62 .71 .94 1.41
Mm.25381
9
KLA  ATP  ATP+KLA
 118130676 Unknown KLA 1.81 1.88 1.96 1.62 1.89 2.44 1.56
ATP .92 .91 1.24 1.01 1.16 2.06 1.95
KLA/ATP 1.62 1.86 1.86 1.41 1.89 2.37 1.97
Mm.30616
3
KLA  ATP  ATP+KLA
 31543508 Unknown KLA .75 .79 .72 .74 .73 .95 1.15
ATP .93 .93 1.13 1.15 1.30 1.17 1.64
KLA/ATP .78 .83 .82 .86 1.02 1.17 1.18
Mm.33138
9
KLA  ATP  ATP+KLA
 158508469 Unknown KLA .80 .79 .81 .82 .72 .64 .50
ATP .95 .85 .56 .48 .30 .33 .46
KLA/ATP .71 .64 .50 .41 .33 .32 .42
Mm.33565
9
KLA  ATP  ATP+KLA
 160333365 Unknown KLA 5.54 4.69 3.93 3.03 2.00 1.91 1.69
ATP .98 .81 1.01 .78 .68 1.71 1.10
KLA/ATP 5.05 4.44 5.07 2.38 1.34 1.88 2.00
Mm.42163
KLA  ATP  ATP+KLA
 157951683 Unknown KLA 1.15 1.26 1.21 1.33 1.13 1.06 .99
ATP 1.07 1.05 1.10 1.32 1.03 1.01 1.00
KLA/ATP 1.19 1.16 1.15 1.47 1.11 1.12 .96
Mm.4387
KLA  ATP  ATP+KLA
 133892666 Unknown KLA .85 .87 .85 .89 .77 .91 1.18
ATP 1.01 1.01 .87 1.07 .75 .86 .93
KLA/ATP .88 .86 .77 .81 .72 .91 .84
Mm.5126
KLA  ATP  ATP+KLA
 158508678 Unknown KLA .70 .71 .73 .79 .87 1.11 1.25
ATP 1.22 1.37 1.08 1.54 1.38 1.01 1.26
KLA/ATP .85 .83 .75 .90 1.12 .96 1.17
Mm.80682
KLA  ATP  ATP+KLA
 94369627 Unknown KLA .96 1.00 .97 .97 1.07 1.05 .99
ATP .97 1.02 .98 1.01 1.01 1.06 .96
KLA/ATP 1.00 .93 1.02 1.08 .98 .95 .97
Myd88
KLA  ATP  ATP+KLA
 NM_010851 myeloid differentiation primary response gene 88 (Myd88), mRNA [NM_010851] KLA 3.35 3.51 3.91 4.13 4.13 3.62 2.53
ATP .99 .96 .79 .75 .93 2.15 1.60
KLA/ATP 3.37 3.52 3.52 3.48 2.81 3.03 3.33
Nfkb1
KLA  ATP  ATP+KLA
 BC050841 nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, mRNA (cDNA clone IMAGE:6392793), complete cds. [BC050841] KLA 5.81 4.96 4.77 3.21 3.37 2.00 1.71
ATP 1.39 1.52 3.25 12.63 13.64 4.80 1.08
KLA/ATP 7.21 8.69 19.53 23.93 11.70 2.85 2.01
Nfkb1
KLA  ATP  ATP+KLA
 M57999 gb|Mouse transcription factor NF-kappa-B DNA binding subunit mRNA, complete cds. [M57999] KLA 8.55 7.87 7.35 6.13 3.51 1.85 1.38
ATP .98 .96 1.21 3.06 5.29 4.67 .69
KLA/ATP 7.32 7.20 8.71 10.82 5.55 2.77 1.54
Nfkbia
KLA  ATP  ATP+KLA
 NM_010907 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA [NM_010907] KLA 18.65 18.46 13.63 17.88 14.25 9.17 7.92
ATP .91 1.09 7.11 32.39 17.44 10.49 1.72
KLA/ATP 15.57 17.66 15.73 23.91 13.83 10.73 9.48
Ngf
KLA  ATP  ATP+KLA
 NM_013609 nerve growth factor (Ngf), transcript variant A, mRNA [NM_013609] KLA .99 .98 .97 .99 .97 1.10 1.05
ATP .94 1.03 .99 1.00 .93 1.05 1.01
KLA/ATP .94 1.01 .99 .98 .98 1.11 1.02
Ntrk1
KLA  ATP  ATP+KLA
 NM_001033124 neurotrophic tyrosine kinase, receptor, type 1 (Ntrk1), mRNA [NM_001033124] KLA .95 .96 1.03 1.03 .95 1.01 1.02
ATP 1.04 .98 .98 1.07 .99 1.01 1.02
KLA/ATP .97 1.03 1.10 1.02 1.05 1.00 .97
Pik3ca
KLA  ATP  ATP+KLA
 ENSMUST00000108243 ens|Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K). [Source:Uniprot/SWISSPROT;Acc:P42337] [ENSMUST00000108243] KLA 1.07 1.01 .91 .90 .98 .96 .86
ATP 1.03 .87 1.12 .63 1.22 1.86 .60
KLA/ATP 1.05 .82 .91 .61 1.17 1.26 .63
Pik3ca
KLA  ATP  ATP+KLA
 NM_008839 phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca), mRNA [NM_008839] KLA 1.15 1.11 1.05 .82 .99 1.03 1.27
ATP .98 1.00 .79 .75 .96 1.32 1.10
KLA/ATP 1.10 .98 .64 .72 .80 1.20 1.41
Pik3cb
KLA  ATP  ATP+KLA
 NM_029094 phosphatidylinositol 3-kinase, catalytic, beta polypeptide (Pik3cb), mRNA [NM_029094] KLA 1.06 1.06 1.03 .73 .68 .98 1.69
ATP 1.04 1.21 .95 1.02 .85 .93 1.73
KLA/ATP 1.15 1.27 .73 .83 .58 .81 1.81
Pik3cd
KLA  ATP  ATP+KLA
 NM_008840 phosphatidylinositol 3-kinase catalytic delta polypeptide (Pik3cd), transcript variant 1, mRNA [NM_008840] KLA 2.28 2.42 3.10 4.17 3.35 2.31 1.34
ATP 1.02 .91 .99 .63 .30 .67 .80
KLA/ATP 2.14 2.23 2.70 1.51 1.17 .85 .72
Pik3cd
KLA  ATP  ATP+KLA
 U86587 phosphatidylinositol 3-kinase catalytic subunit p110 delta mRNA, complete cds. [U86587] KLA 2.21 2.24 3.71 3.17 3.67 2.66 1.48
ATP 1.00 1.03 .93 .96 .46 .75 .97
KLA/ATP 2.27 2.32 1.97 2.02 1.01 .99 .98
Pik3cg
KLA  ATP  ATP+KLA
 NM_020272 phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg), mRNA [NM_020272] KLA .53 .53 .61 .64 .97 .86 .79
ATP 1.01 1.13 .88 .89 .52 .53 .53
KLA/ATP .58 .53 .43 .60 .40 .43 .62
Pik3r1
KLA  ATP  ATP+KLA
 NM_001077495 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 2, mRNA [NM_001077495] KLA 1.05 1.07 1.03 1.00 1.01 1.20 .85
ATP .97 1.02 1.48 1.42 1.76 1.33 1.23
KLA/ATP 1.11 1.12 1.06 1.17 1.24 .99 1.12
Pik3r2
KLA  ATP  ATP+KLA
 NM_008841 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2), mRNA [NM_008841] KLA .50 .50 .48 .43 .46 .66 .75
ATP .78 .68 .45 .43 .28 .57 1.37
KLA/ATP .49 .38 .32 .33 .38 .67 1.10
Pik3r3
KLA  ATP  ATP+KLA
 NM_181585 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) (Pik3r3), mRNA [NM_181585] KLA 1.59 1.49 1.37 1.17 1.05 1.55 1.41
ATP 1.12 1.00 1.33 1.70 2.01 2.37 2.02
KLA/ATP 1.63 1.54 1.58 1.70 2.43 2.68 1.92
Pik3r5
KLA  ATP  ATP+KLA
 NM_177320 phosphoinositide-3-kinase, regulatory subunit 5, p101 (Pik3r5), mRNA [NM_177320] KLA 3.57 3.58 4.16 3.54 4.11 2.59 2.39
ATP 1.08 1.08 .93 1.67 3.11 1.88 1.34
KLA/ATP 3.91 3.70 3.30 3.80 2.70 2.04 3.00
Ppp3ca
KLA  ATP  ATP+KLA
 NM_008913 protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca), mRNA [NM_008913] KLA .76 .85 .81 .85 .73 .70 .52
ATP .96 .78 .55 .46 .31 .33 .48
KLA/ATP .74 .64 .52 .42 .37 .36 .45
Ppp3cb
KLA  ATP  ATP+KLA
 AK135203 12 days embryo male wolffian duct includes surrounding region cDNA, RIKEN full-length enriched library, clone:6720421K10 product:protein phosphatase 3, catalytic subunit, beta isoform, full insert sequence. [AK135203] KLA 1.74 1.57 1.91 1.59 1.47 1.26 1.40
ATP 1.17 1.03 1.30 1.00 .81 .62 1.37
KLA/ATP 1.68 1.70 1.91 1.37 1.09 .47 1.13
Ppp3cb
KLA  ATP  ATP+KLA
 AK171904 activated spleen cDNA, RIKEN full-length enriched library, clone:F830018L06 product:Protein phosphatase 3 catalytic subunit beta3 (EC 3.1.3.16) (Serine [AK171904] KLA 1.29 1.29 1.21 1.15 1.22 1.13 1.28
ATP .90 .86 .80 .98 .94 .73 .92
KLA/ATP 1.06 1.03 .77 1.04 .92 .68 .90
Ppp3cb
KLA  ATP  ATP+KLA
 NM_008914 protein phosphatase 3, catalytic subunit, beta isoform (Ppp3cb), mRNA [NM_008914] KLA 1.21 1.29 1.38 1.24 1.29 1.08 1.23
ATP 1.15 1.31 1.09 1.29 .86 .60 .64
KLA/ATP 1.33 1.40 1.04 1.28 .79 .58 .73
Ppp3cc
KLA  ATP  ATP+KLA
 AK037563 16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130026K22 product:unclassifiable, full insert sequence [AK037563] KLA 1.27 1.18 1.21 1.15 1.01 .92 1.36
ATP .96 1.09 1.10 1.03 .85 1.06 1.47
KLA/ATP 1.17 1.24 1.07 1.13 .91 .88 1.36
Ppp3cc
KLA  ATP  ATP+KLA
 NM_008915 protein phosphatase 3, catalytic subunit, gamma isoform (Ppp3cc), mRNA [NM_008915] KLA 1.64 1.81 1.79 1.35 .90 .70 1.31
ATP .90 .90 1.13 .93 .86 1.40 1.60
KLA/ATP 1.45 1.62 1.74 1.47 1.04 1.01 1.31
Ppp3r1
KLA  ATP  ATP+KLA
 NM_024459 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) (Ppp3r1), mRNA [NM_024459] KLA 1.02 1.17 .93 1.27 1.15 1.30 1.30
ATP .97 .95 .77 .91 .99 1.18 1.10
KLA/ATP 1.12 1.04 .88 1.00 1.10 1.10 1.07
Ppp3r2
KLA  ATP  ATP+KLA
 NM_001004025 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II) (Ppp3r2), mRNA [NM_001004025] KLA 1.03 1.05 1.06 1.08 1.12 1.05 1.04
ATP 1.00 1.02 1.04 1.04 .99 .99 1.01
KLA/ATP 1.04 1.12 1.03 1.09 1.00 .99 1.00
Prkaca
KLA  ATP  ATP+KLA
 NM_008854 protein kinase, cAMP dependent, catalytic, alpha (Prkaca), mRNA [NM_008854] KLA .71 .74 .72 .70 .72 .84 .85
ATP 1.05 .98 .89 .92 .76 .60 1.02
KLA/ATP .79 .74 .55 .65 .60 .65 .93
Prkacb
KLA  ATP  ATP+KLA
 NM_011100 protein kinase, cAMP dependent, catalytic, beta (Prkacb), mRNA [NM_011100] KLA .69 .70 .66 .58 .51 .55 .59
ATP 1.02 1.19 .97 1.01 .69 .38 .56
KLA/ATP .72 .73 .57 .62 .47 .41 .45
Prkar1a
KLA  ATP  ATP+KLA
 NM_021880 protein kinase, cAMP dependent regulatory, type I, alpha (Prkar1a), mRNA [NM_021880] KLA 1.03 1.01 1.14 .97 1.05 .93 .85
ATP 1.14 1.32 1.06 1.24 1.00 .62 .68
KLA/ATP 1.16 1.24 .83 1.13 .84 .79 .48
Prkar1b
KLA  ATP  ATP+KLA
 NM_008923 protein kinase, cAMP dependent regulatory, type I beta (Prkar1b), mRNA [NM_008923] KLA 1.02 1.05 .85 .95 .90 .98 1.26
ATP 1.05 1.12 .95 1.12 1.12 1.06 1.23
KLA/ATP 1.00 .97 .81 .90 .93 1.06 1.05
Prkar2a
KLA  ATP  ATP+KLA
 NM_008924 protein kinase, cAMP dependent regulatory, type II alpha (Prkar2a), mRNA [NM_008924] KLA .70 .65 .56 .52 .41 .48 .82
ATP 1.05 1.27 .85 1.05 .74 .70 .84
KLA/ATP .71 .72 .45 .56 .41 .51 .71
Prkar2b
KLA  ATP  ATP+KLA
 NM_011158 protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), mRNA [NM_011158] KLA .83 .76 .76 .67 .34 .43 .62
ATP .82 .79 1.08 .71 .69 2.46 .55
KLA/ATP .65 .74 .95 .63 .42 .70 1.19
Prkx
KLA  ATP  ATP+KLA
 NM_016979 protein kinase, X-linked (Prkx), mRNA [NM_016979] KLA 3.61 3.79 4.67 4.66 4.85 4.19 1.43
ATP .98 .90 .63 .61 1.12 1.90 1.29
KLA/ATP 3.56 3.36 2.62 2.06 2.26 2.87 2.31
Rela
KLA  ATP  ATP+KLA
 NM_009045 v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela), mRNA [NM_009045] KLA 2.05 2.05 2.07 1.75 1.83 1.58 1.33
ATP 1.03 1.08 1.10 1.44 1.61 2.48 1.05
KLA/ATP 2.17 2.27 2.05 2.47 1.93 2.35 2.02
Ripk1
KLA  ATP  ATP+KLA
 NM_009068 receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1), mRNA [NM_009068] KLA 1.32 1.33 1.50 1.09 1.00 1.11 1.13
ATP .98 .94 .60 .59 1.35 1.56 1.45
KLA/ATP 1.48 1.30 1.01 1.05 1.36 1.53 1.37
Tnf
KLA  ATP  ATP+KLA
 NM_013693 tumor necrosis factor (Tnf), mRNA [NM_013693] KLA 13.35 12.76 10.71 9.03 10.64 7.39 8.32
ATP 2.01 2.48 8.27 19.20 9.72 4.09 1.49
KLA/ATP 12.72 15.76 12.73 17.34 5.10 3.61 6.07
Tnfrsf10
b
KLA  ATP  ATP+KLA
 NM_020275 tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), mRNA [NM_020275] KLA 1.29 1.24 1.23 1.14 .96 .88 .87
ATP .99 1.04 1.06 1.14 .95 1.10 1.15
KLA/ATP 1.26 1.26 1.21 1.23 1.03 .93 .93
Tnfrsf1a
KLA  ATP  ATP+KLA
 NM_011609 tumor necrosis factor receptor superfamily, member 1a (Tnfrsf1a), mRNA [NM_011609] KLA 1.74 1.71 1.90 2.16 1.95 1.74 1.16
ATP .95 .83 .55 .41 .41 1.55 1.32
KLA/ATP 1.58 1.49 1.19 1.03 .98 2.02 2.10
Tnfsf10
KLA  ATP  ATP+KLA
 NM_009425 tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10), mRNA [NM_009425] KLA 31.48 31.73 32.62 36.94 28.34 23.40 4.96
ATP 1.06 .93 1.28 1.24 1.07 2.74 3.33
KLA/ATP 28.07 30.23 43.53 33.98 27.97 18.71 17.43
Tradd
KLA  ATP  ATP+KLA
 NM_001033161 TNFRSF1A-associated via death domain (Tradd), mRNA [NM_001033161] KLA .77 .71 .82 .89 .89 1.11 1.06
ATP 1.00 .90 1.01 .73 .59 1.34 1.50
KLA/ATP .79 .73 .83 .63 .72 1.11 1.73
Traf2
KLA  ATP  ATP+KLA
 NM_009422 Tnf receptor-associated factor 2 (Traf2), mRNA [NM_009422] KLA 3.38 3.62 3.49 3.36 3.49 3.39 2.68
ATP .97 1.04 1.00 1.10 1.54 2.40 1.55
KLA/ATP 3.38 3.16 2.93 2.74 2.67 3.11 4.70
Trp53
KLA  ATP  ATP+KLA
 NM_011640 transformation related protein 53 (Trp53), mRNA [NM_011640] KLA 1.25 1.37 1.11 .86 .72 .71 .95
ATP 1.15 1.32 .90 1.85 1.26 .68 .70
KLA/ATP 1.66 1.49 .80 1.76 .81 .65 .74
Xiap
KLA  ATP  ATP+KLA
 NM_009688 X-linked inhibitor of apoptosis (Xiap), mRNA [NM_009688] KLA 1.61 1.63 1.62 1.52 1.34 1.27 1.11
ATP 1.03 1.01 .99 .96 .88 1.19 1.25
KLA/ATP 1.64 1.63 1.54 1.33 1.08 1.19 1.72