Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: TGF-beta signaling pathway (mmu04350)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Acvr1
KLA  ATP  ATP+KLA
 NM_007394 activin A receptor, type 1 (Acvr1), transcript variant 2, mRNA [NM_007394] KLA 2.86 2.67 2.99 2.33 1.67 1.27 1.19
ATP 1.08 1.12 .80 .69 .92 1.14 1.07
KLA/ATP 2.85 2.94 2.29 1.72 1.01 1.36 1.65
Acvr1b
KLA  ATP  ATP+KLA
 AK154578 NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630048N11 product:activin A receptor, type 1B, full insert sequence [AK154578] KLA .92 .81 .83 1.45 2.62 1.73 1.65
ATP 1.06 1.05 .97 .57 1.31 2.68 1.19
KLA/ATP .72 .72 .90 .77 1.56 2.22 1.98
Acvr1b
KLA  ATP  ATP+KLA
 NM_007395 activin A receptor, type 1B (Acvr1b), mRNA [NM_007395] KLA 1.00 .95 .98 1.13 1.27 1.23 1.23
ATP 1.02 1.04 .96 .98 1.23 1.33 1.14
KLA/ATP .97 1.01 1.07 1.03 1.12 1.51 1.51
Acvr1c
KLA  ATP  ATP+KLA
 NM_001033369 activin A receptor, type IC (Acvr1c), transcript variant 2, mRNA [NM_001033369] KLA 1.00 .97 1.03 1.01 .99 1.01 1.04
ATP 1.00 .94 1.01 1.00 1.00 1.05 .98
KLA/ATP 1.01 1.01 .99 1.09 1.05 1.03 1.04
Acvr2a
KLA  ATP  ATP+KLA
 AK050252 adult male liver tumor cDNA, RIKEN full-length enriched library, clone:C730031B13 product:hypothetical protein, full insert sequence. [AK050252] KLA .97 .95 1.02 1.08 1.00 1.08 1.10
ATP .97 1.00 .96 1.07 1.01 1.01 1.03
KLA/ATP .97 .95 .98 1.05 1.28 1.13 .95
Acvr2a
KLA  ATP  ATP+KLA
 NM_007396 activin receptor IIA (Acvr2a), mRNA [NM_007396] KLA 1.73 1.69 1.95 1.90 1.85 1.44 1.34
ATP .99 1.01 1.09 1.12 1.12 1.51 1.23
KLA/ATP 1.67 1.67 1.44 1.20 .95 1.29 1.72
Acvr2b
KLA  ATP  ATP+KLA
 NM_007397 activin receptor IIB (Acvr2b), mRNA [NM_007397] KLA .67 .63 .74 .69 .73 .71 .68
ATP .90 .88 .87 .76 .79 .97 .80
KLA/ATP .63 .61 .72 .66 .77 .78 .71
Amh
KLA  ATP  ATP+KLA
 NM_007445 anti-Mullerian hormone (Amh), mRNA [NM_007445] KLA 1.02 .96 .94 1.02 1.03 .96 .97
ATP .95 1.06 1.00 1.21 .99 1.00 .98
KLA/ATP 1.01 .96 1.02 1.05 .94 .96 .97
Amhr2
KLA  ATP  ATP+KLA
 NM_144547 anti-Mullerian hormone type 2 receptor (Amhr2), mRNA [NM_144547] KLA .96 1.00 .96 1.01 1.11 1.23 1.22
ATP 1.00 1.06 1.12 1.34 1.56 1.31 1.09
KLA/ATP 1.05 .99 .98 1.19 2.37 1.86 1.66
BI646741
KLA  ATP  ATP+KLA
 BI646741 gb|BI646741 603279769F1 NCI_CGAP_Mam3 Mus musculus cDNA clone IMAGE:5320025 5, mRNA sequence [BI646741] KLA .55 .54 .47 .54 .65 1.09 1.60
ATP 1.04 .99 .93 1.08 2.49 .79 .88
KLA/ATP .54 .49 .54 .60 1.21 .97 1.54
Bambi
KLA  ATP  ATP+KLA
 NM_026505 BMP and activin membrane-bound inhibitor, homolog (Xenopus laevis) (Bambi), mRNA [NM_026505] KLA 1.52 1.41 1.12 .61 .61 1.26 .84
ATP 1.33 1.93 2.43 2.79 2.83 2.18 1.24
KLA/ATP 1.52 1.79 2.51 2.89 3.90 4.00 1.23
Bmp2
KLA  ATP  ATP+KLA
 NM_007553 bone morphogenetic protein 2 (Bmp2), mRNA [NM_007553] KLA 1.18 1.19 1.30 1.16 1.02 1.07 .99
ATP 1.05 1.18 1.79 4.60 2.95 2.38 .96
KLA/ATP 1.26 1.52 1.77 2.64 1.78 1.47 .97
Bmp4
KLA  ATP  ATP+KLA
 NM_007554 bone morphogenetic protein 4 (Bmp4), mRNA [NM_007554] KLA 1.02 1.04 1.04 1.09 1.08 1.12 1.06
ATP .98 1.00 1.05 1.04 .94 .97 1.00
KLA/ATP .99 1.03 1.07 1.04 .99 .99 .97
Bmp5
KLA  ATP  ATP+KLA
 AK079078 adult male diencephalon cDNA, RIKEN full-length enriched library, clone:9330158F20 product:unclassifiable, full insert sequence. [AK079078] KLA 1.04 1.02 1.02 1.01 .95 .94 1.05
ATP .98 .98 .99 .99 1.01 1.06 1.04
KLA/ATP .97 1.03 .98 .99 1.00 1.13 1.00
Bmp5
KLA  ATP  ATP+KLA
 NM_007555 bone morphogenetic protein 5 (Bmp5), mRNA [NM_007555] KLA .95 .99 1.00 1.02 1.04 1.07 1.07
ATP .97 1.07 .99 1.06 1.02 1.02 1.04
KLA/ATP 1.03 1.02 1.09 1.06 1.11 1.06 1.02
Bmp6
KLA  ATP  ATP+KLA
 NM_007556 bone morphogenetic protein 6 (Bmp6), mRNA [NM_007556] KLA 1.03 1.02 .97 .97 1.01 1.01 1.00
ATP .99 1.00 .96 .97 .94 .98 1.01
KLA/ATP .98 1.06 1.04 1.01 1.02 1.00 .98
Bmp7
KLA  ATP  ATP+KLA
 NM_007557 bone morphogenetic protein 7 (Bmp7), mRNA [NM_007557] KLA 1.00 .98 1.00 1.00 .99 1.00 1.00
ATP 1.00 .99 1.04 .97 1.01 1.01 1.01
KLA/ATP .98 .97 1.02 1.00 1.03 1.00 .99
Bmp8a
KLA  ATP  ATP+KLA
 NM_007558 bone morphogenetic protein 8a (Bmp8a), mRNA [NM_007558] KLA .95 .93 .96 1.03 1.00 .92 .98
ATP 1.07 .96 .97 1.50 1.90 1.94 1.64
KLA/ATP .98 .99 .98 1.24 1.43 1.49 1.37
Bmp8b
KLA  ATP  ATP+KLA
 NM_007559 bone morphogenetic protein 8b (Bmp8b), mRNA [NM_007559] KLA 1.12 1.03 1.05 1.06 1.07 1.05 1.04
ATP .97 1.03 1.04 .98 1.00 .94 1.04
KLA/ATP 1.06 1.05 .98 1.02 1.04 .95 1.07
Bmpr1a
KLA  ATP  ATP+KLA
 NM_009758 bone morphogenetic protein receptor, type 1A (Bmpr1a), mRNA [NM_009758] KLA .98 .98 .93 .89 .89 .92 1.00
ATP 1.03 .99 .98 .87 .97 1.08 1.03
KLA/ATP .99 1.00 .89 .85 .94 1.01 .92
Bmpr1b
KLA  ATP  ATP+KLA
 NM_007560 bone morphogenetic protein receptor, type 1B (Bmpr1b), mRNA [NM_007560] KLA .99 1.00 .93 .94 .98 .90 .94
ATP 1.11 1.06 .94 .95 .98 .88 .95
KLA/ATP .84 .92 .95 .90 .89 .90 .89
Bmpr2
KLA  ATP  ATP+KLA
 AK011534 10 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2610024H22 product:unclassifiable, full insert sequence. [AK011534] KLA 1.17 1.10 1.17 1.35 1.31 1.08 .67
ATP 1.01 .89 .93 .55 .59 .82 .57
KLA/ATP 1.17 .99 1.12 .63 .74 .67 .50
Bmpr2
KLA  ATP  ATP+KLA
 AK140220 adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230350M15 product:unclassifiable, full insert sequence [AK140220] KLA 1.21 1.16 1.17 1.25 1.42 .90 .98
ATP 1.20 1.22 .96 .97 .88 1.00 .76
KLA/ATP 1.20 1.36 .96 1.00 .84 .91 .94
Bmpr2
KLA  ATP  ATP+KLA
 NM_007561 bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2), mRNA [NM_007561] KLA 1.39 1.34 1.46 1.67 1.59 1.39 1.15
ATP .94 .95 1.10 .88 .91 1.24 1.31
KLA/ATP 1.33 1.36 1.39 1.13 1.15 1.34 2.01
Cdkn2b
KLA  ATP  ATP+KLA
 NM_007670 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (Cdkn2b), mRNA [NM_007670] KLA .70 .75 .94 1.44 1.66 .55 .81
ATP 1.02 .89 1.00 .86 1.33 3.87 .57
KLA/ATP .71 .77 .91 .94 .74 1.64 1.17
Chrd
KLA  ATP  ATP+KLA
 NM_009893 chordin (Chrd), mRNA [NM_009893] KLA 1.16 1.12 1.11 1.11 1.48 1.45 1.43
ATP 1.01 1.09 1.11 1.12 1.01 1.10 1.16
KLA/ATP 1.07 1.16 1.24 1.33 1.12 1.07 1.43
Crebbp
KLA  ATP  ATP+KLA
 AK048818 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230072N21 product:hypothetical protein, full insert sequence [AK048818] KLA 1.44 1.19 1.26 1.25 1.25 1.36 1.24
ATP .98 .90 1.04 1.11 1.95 2.72 1.51
KLA/ATP 1.17 1.27 1.45 1.28 1.98 2.80 2.52
Crebbp
KLA  ATP  ATP+KLA
 NM_001025432 CREB binding protein (Crebbp), mRNA [NM_001025432] KLA .97 1.01 .98 1.06 1.05 .99 1.07
ATP 1.07 1.05 .96 1.01 1.15 1.14 1.00
KLA/ATP 1.01 .97 .97 1.00 1.03 1.23 1.13
Crebbp
KLA  ATP  ATP+KLA
 S66385 gb|CREB-binding protein [mice, brain, mRNA Partial, 7326 nt]. [S66385] KLA 1.00 .98 1.08 .98 1.04 1.07 1.08
ATP .99 .98 .99 1.09 1.13 1.08 1.05
KLA/ATP 1.06 1.00 1.05 1.03 1.02 1.14 1.11
Cul1
KLA  ATP  ATP+KLA
 NM_012042 cullin 1 (Cul1), mRNA [NM_012042] KLA 1.54 1.57 1.59 1.36 1.13 1.06 1.15
ATP 1.02 1.15 1.00 1.02 1.00 1.16 1.10
KLA/ATP 1.54 1.68 1.30 1.46 .98 1.02 1.12
Dcn
KLA  ATP  ATP+KLA
 AK052759 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630044L13 product:unclassifiable, full insert sequence. [AK052759] KLA 1.02 1.03 1.01 .96 .94 1.04 1.03
ATP .97 1.02 1.05 .96 .93 .99 1.01
KLA/ATP 1.03 1.01 1.00 1.02 .97 1.01 1.04
Dcn
KLA  ATP  ATP+KLA
 NM_007833 decorin (Dcn), mRNA [NM_007833] KLA 1.21 1.36 1.45 1.54 1.74 2.09 2.92
ATP 1.01 .98 1.09 1.22 1.20 1.70 2.43
KLA/ATP 1.19 1.34 1.60 1.75 1.99 3.41 18.56
E2f4
KLA  ATP  ATP+KLA
 NM_148952 E2F transcription factor 4 (E2f4), mRNA [NM_148952] KLA 1.12 1.11 1.05 1.36 1.41 1.24 1.32
ATP 1.09 1.10 1.06 1.33 1.15 1.26 1.16
KLA/ATP 1.10 1.21 1.06 1.25 .90 1.12 1.41
E2f5
KLA  ATP  ATP+KLA
 AK028856 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732463D08 product:unclassifiable, full insert sequence [AK028856] KLA 1.04 1.04 .97 .94 1.02 1.03 1.06
ATP .94 .95 1.05 1.13 1.07 .99 1.04
KLA/ATP 1.01 1.02 .96 1.01 1.04 1.02 1.00
E2f5
KLA  ATP  ATP+KLA
 NM_007892 E2F transcription factor 5 (E2f5), mRNA [NM_007892] KLA 2.26 2.26 2.58 2.14 1.76 1.32 1.34
ATP .94 1.03 1.08 1.20 1.55 2.09 .79
KLA/ATP 2.20 2.30 2.17 2.85 2.23 2.03 1.50
E2f5
KLA  ATP  ATP+KLA
 X86925 gb|M.musculus mRNA for E2F-5 protein. [X86925] KLA 2.12 2.10 2.40 2.23 1.81 1.31 1.25
ATP .95 .91 1.19 1.12 1.70 2.41 .77
KLA/ATP 2.23 2.10 2.79 2.62 2.72 2.29 1.55
Ep300
KLA  ATP  ATP+KLA
 AK042627 7 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:A730011L11 product:P300 TRANSCRIPTION COACTIVATOR (FRAGMENT) homolog [Mus sp], full insert sequence. [AK042627] KLA 1.02 .95 .92 1.04 1.01 1.00 1.05
ATP 1.06 .89 .88 .89 1.00 .90 1.07
KLA/ATP 1.10 1.02 .87 .91 1.04 .97 .98
Ep300
KLA  ATP  ATP+KLA
 NM_177821 E1A binding protein p300 (Ep300), mRNA [NM_177821] KLA 1.61 1.26 1.57 1.38 1.78 1.41 1.40
ATP 1.34 1.60 1.11 1.08 1.16 1.05 1.15
KLA/ATP 1.86 1.94 1.18 1.56 1.71 1.42 2.05
Fst
KLA  ATP  ATP+KLA
 NM_008046 follistatin (Fst), mRNA [NM_008046] KLA 3.44 4.09 5.28 3.56 2.00 1.24 1.14
ATP .97 .99 1.19 1.17 1.21 1.35 1.14
KLA/ATP 3.94 4.27 4.94 4.55 2.33 1.47 1.22
Gdf5
KLA  ATP  ATP+KLA
 NM_008109 growth differentiation factor 5 (Gdf5), mRNA [NM_008109] KLA 1.00 .93 .91 .99 1.06 1.04 1.16
ATP .99 .98 .97 .98 .89 .97 1.01
KLA/ATP .88 .96 1.01 .95 .89 .97 1.03
Gdf6
KLA  ATP  ATP+KLA
 NM_013526 growth differentiation factor 6 (Gdf6), mRNA [NM_013526] KLA .91 1.01 .99 1.02 .96 1.07 1.01
ATP .99 1.00 1.04 1.04 1.01 1.03 .98
KLA/ATP .98 .93 .98 .99 1.05 1.05 1.01
Gdf7
KLA  ATP  ATP+KLA
 NM_013527 growth differentiation factor 7 (Gdf7), mRNA [NM_013527] KLA .78 .75 .77 .90 .93 .92 .94
ATP .94 .95 1.01 .86 .92 .99 1.00
KLA/ATP .76 .73 .88 .82 .93 .86 .82
Id1
KLA  ATP  ATP+KLA
 NM_010495 inhibitor of DNA binding 1 (Id1), mRNA [NM_010495] KLA .72 .71 .65 1.22 .65 .61 .28
ATP .42 .19 .66 4.43 2.48 1.03 1.45
KLA/ATP .39 .23 .64 4.32 4.15 1.68 .89
Id2
KLA  ATP  ATP+KLA
 NM_010496 inhibitor of DNA binding 2 (Id2), mRNA [NM_010496] KLA .91 1.00 1.04 1.09 1.46 1.70 1.98
ATP 1.17 1.43 3.42 12.70 9.83 2.42 4.02
KLA/ATP 1.07 1.16 1.76 7.26 7.29 1.58 4.38
Id3
KLA  ATP  ATP+KLA
 NM_008321 inhibitor of DNA binding 3 (Id3), mRNA [NM_008321] KLA .67 .80 .84 1.69 1.16 .85 .53
ATP .87 .88 4.53 13.40 10.68 2.19 .74
KLA/ATP .79 .80 1.70 6.53 5.98 2.60 1.73
Id4
KLA  ATP  ATP+KLA
 NM_031166 inhibitor of DNA binding 4 (Id4), mRNA [NM_031166] KLA 1.01 1.03 .98 1.00 1.02 .97 1.00
ATP 1.00 1.00 1.00 1.04 1.01 .99 .97
KLA/ATP 1.01 1.00 .90 1.08 1.02 1.00 1.00
Ifng
KLA  ATP  ATP+KLA
 NM_008337 interferon gamma (Ifng), mRNA [NM_008337] KLA 1.05 1.02 1.01 1.01 1.01 1.04 1.00
ATP 1.00 1.01 1.01 .98 .97 1.04 1.03
KLA/ATP 1.01 1.01 1.06 1.10 1.24 1.10 1.04
Inhba
KLA  ATP  ATP+KLA
 NM_008380 inhibin beta-A (Inhba), mRNA [NM_008380] KLA 7.13 7.30 8.51 8.11 5.73 5.18 5.94
ATP 1.03 1.23 3.72 7.04 13.27 17.63 11.55
KLA/ATP 6.97 10.73 20.43 21.90 23.12 20.33 20.24
Inhbb
KLA  ATP  ATP+KLA
 NM_008381 inhibin beta-B (Inhbb), mRNA [NM_008381] KLA 1.13 1.17 1.11 1.13 1.04 .98 .97
ATP 1.00 1.02 1.01 1.00 1.00 .97 1.00
KLA/ATP 1.22 1.23 1.24 1.07 1.05 1.00 .96
Inhbc
KLA  ATP  ATP+KLA
 NM_010565 inhibin beta-C (Inhbc), mRNA [NM_010565] KLA 1.01 .97 1.01 .99 .94 .96 .99
ATP 1.01 1.02 .95 .99 .93 .97 .96
KLA/ATP .91 .98 .98 .95 .94 .99 .92
Inhbe
KLA  ATP  ATP+KLA
 NM_008382 inhibin beta E (Inhbe), mRNA [NM_008382] KLA .97 1.02 1.12 1.15 1.03 1.06 1.03
ATP 1.03 .99 1.09 1.10 1.03 1.16 .73
KLA/ATP 1.08 1.07 1.13 1.07 1.08 1.04 1.05
Lefty1
KLA  ATP  ATP+KLA
 NM_010094 left right determination factor 1 (Lefty1), mRNA [NM_010094] KLA .68 .71 .64 .67 .64 .68 .64
ATP 1.12 1.02 .96 .90 .70 .62 .55
KLA/ATP .64 .66 .66 .63 .64 .64 .43
Lefty2
KLA  ATP  ATP+KLA
 NM_177099 Left-right determination factor 2 (Lefty2), mRNA [NM_177099] KLA .97 .97 1.04 .99 1.03 1.00 1.06
ATP .99 .91 .99 1.03 .92 .98 .88
KLA/ATP .97 1.19 .97 1.01 1.00 1.02 .95
Ltbp1
KLA  ATP  ATP+KLA
 NM_019919 latent transforming growth factor beta binding protein 1 (Ltbp1), transcript variant 1, mRNA [NM_019919] KLA 1.01 1.04 .98 .97 1.06 1.01 1.00
ATP 1.02 1.08 1.02 .99 .99 1.00 .97
KLA/ATP 1.03 .99 1.02 1.02 .95 .97 1.07
Mapk1
KLA  ATP  ATP+KLA
 NM_001038663 mitogen-activated protein kinase 1 (Mapk1), transcript variant 2, mRNA [NM_001038663] KLA .97 1.03 .93 .86 .79 1.01 1.04
ATP .96 1.18 1.01 1.13 .84 1.04 1.16
KLA/ATP .99 .99 .84 .87 .63 .96 1.26
Mapk1
KLA  ATP  ATP+KLA
 NM_011949 mitogen-activated protein kinase 1 (Mapk1), transcript variant 1, mRNA [NM_011949] KLA .88 .80 .80 .73 .75 .76 .65
ATP .97 .96 1.06 .88 .90 .68 .48
KLA/ATP .82 .81 .78 .65 .64 .64 .45
Mapk3
KLA  ATP  ATP+KLA
 NM_011952 mitogen-activated protein kinase 3 (Mapk3), mRNA [NM_011952] KLA .81 .85 .88 .72 .79 .73 .90
ATP 1.13 1.30 .92 1.48 1.08 .68 1.03
KLA/ATP 1.01 1.01 .66 1.13 .77 .77 1.16
Mm.4744
KLA  ATP  ATP+KLA
 6679980 Unknown KLA 1.08 1.04 1.02 1.05 .98 1.02 .72
ATP 1.02 1.12 .98 1.06 1.02 1.00 1.00
KLA/ATP .96 1.00 1.11 1.04 .99 .97 1.01
Mm.87078
KLA  ATP  ATP+KLA
 42734479 Unknown KLA 1.02 1.05 .98 .98 1.04 1.01 1.08
ATP 1.03 .97 .97 1.09 .94 1.05 1.12
KLA/ATP 1.02 .92 1.01 1.01 1.09 1.14 1.08
Myc
KLA  ATP  ATP+KLA
 NM_010849 myelocytomatosis oncogene (Myc), mRNA [NM_010849] KLA .38 .31 .45 .45 .49 .35 .33
ATP 1.05 1.09 1.72 4.41 1.28 .45 .76
KLA/ATP .37 .30 .44 1.23 .34 .17 .19
Nodal
KLA  ATP  ATP+KLA
 X70514 gb|M. musculus nodal gene, a TGF-beta-like gene [X70514] KLA 1.09 1.21 1.24 1.20 1.35 1.23 1.25
ATP 1.03 1.07 1.11 1.05 1.10 1.09 1.05
KLA/ATP 1.17 1.26 1.17 1.15 1.17 1.04 1.11
Nog
KLA  ATP  ATP+KLA
 NM_008711 noggin (Nog), mRNA [NM_008711] KLA 1.18 1.10 1.11 1.08 1.14 1.20 1.08
ATP 1.02 1.08 1.22 1.14 1.04 1.18 1.16
KLA/ATP 1.13 1.11 1.47 1.24 1.20 1.22 1.25
Pitx2
KLA  ATP  ATP+KLA
 AK034846 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430046L11 product:paired-like homeodomain transcription factor 2, full insert sequence [AK034846] KLA .96 .95 .96 .98 1.07 .98 1.02
ATP 1.05 1.02 .82 1.02 1.05 1.03 1.03
KLA/ATP .95 .99 1.07 1.00 .96 1.08 1.02
Pitx2
KLA  ATP  ATP+KLA
 NM_001042502 paired-like homeodomain transcription factor 2 (Pitx2), transcript variant 3, mRNA [NM_001042502] KLA .99 .97 1.06 .99 .98 1.00 .97
ATP 1.09 .99 .99 .95 .99 .96 .97
KLA/ATP 1.02 .99 .99 .94 1.05 .93 .94
Ppp2ca
KLA  ATP  ATP+KLA
 NM_019411 protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Ppp2ca), mRNA [NM_019411] KLA 1.17 1.13 1.18 1.20 1.54 1.45 1.34
ATP 1.09 1.20 1.07 1.33 1.56 2.04 1.43
KLA/ATP 1.14 1.17 1.15 1.49 1.59 2.37 2.02
Ppp2cb
KLA  ATP  ATP+KLA
 NM_017374 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), mRNA [NM_017374] KLA 1.32 1.33 1.37 1.24 1.27 1.09 1.18
ATP .94 .93 .82 .91 1.22 2.01 1.08
KLA/ATP 1.24 1.14 .80 .97 1.13 1.54 1.18
Ppp2r1a
KLA  ATP  ATP+KLA
 NM_016891 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (Ppp2r1a), mRNA [NM_016891] KLA 1.44 1.39 1.47 1.37 1.69 1.33 1.16
ATP 1.18 1.55 .85 1.67 1.38 .99 1.24
KLA/ATP 1.66 1.98 .97 2.33 1.41 1.65 1.38
Ppp2r1b
KLA  ATP  ATP+KLA
 NM_001034085 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform (Ppp2r1b), transcript variant 1, mRNA [NM_001034085] KLA 1.26 1.17 1.14 1.13 1.12 1.11 .99
ATP .90 .90 .96 .98 1.59 1.71 1.16
KLA/ATP 1.23 1.16 .99 1.00 1.54 1.34 1.24
Ppp2r1b
KLA  ATP  ATP+KLA
 NM_028614 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform (Ppp2r1b), transcript variant 2, mRNA [NM_028614] KLA 2.38 2.38 2.53 1.80 1.52 .95 1.16
ATP 1.17 1.29 1.04 1.09 1.16 1.19 1.00
KLA/ATP 2.59 2.78 1.82 2.31 1.34 1.03 .75
Rbl1
KLA  ATP  ATP+KLA
 NM_011249 retinoblastoma-like 1 (p107) (Rbl1), mRNA [NM_011249] KLA 3.37 3.24 4.88 3.79 2.52 1.65 .61
ATP 1.08 1.11 1.29 .91 .48 .56 .53
KLA/ATP 3.36 3.65 4.38 3.36 2.12 1.71 1.31
Rbx1
KLA  ATP  ATP+KLA
 NM_019712 ring-box 1 (Rbx1), mRNA [NM_019712] KLA 1.04 1.01 .98 1.09 1.06 1.14 1.09
ATP .92 .89 1.13 1.16 1.68 1.07 .83
KLA/ATP .99 .99 1.25 1.31 2.63 2.06 .67
Rhoa
KLA  ATP  ATP+KLA
 NM_016802 ras homolog gene family, member A (Rhoa), mRNA [NM_016802] KLA .93 1.00 1.07 .97 1.08 1.06 1.02
ATP .93 .88 .49 .61 .63 .78 1.05
KLA/ATP .94 .92 .59 .63 .61 .78 1.12
Rock1
KLA  ATP  ATP+KLA
 NM_009071 Rho-associated coiled-coil containing protein kinase 1 (Rock1), mRNA [NM_009071] KLA 2.40 2.48 2.37 3.07 1.94 1.42 1.21
ATP .95 .92 .87 .70 1.13 1.74 .98
KLA/ATP 2.27 2.35 2.56 1.60 1.65 1.56 1.23
Rock2
KLA  ATP  ATP+KLA
 NM_009072 Rho-associated coiled-coil containing protein kinase 2 (Rock2), mRNA [NM_009072] KLA .99 .92 .83 .87 .73 .74 1.04
ATP 1.07 1.31 1.16 1.02 1.02 1.03 .88
KLA/ATP 1.00 1.07 .93 .85 .69 .63 .81
Rps6kb1
KLA  ATP  ATP+KLA
 NM_001114334 ribosomal protein S6 kinase, polypeptide 1 (Rps6kb1), transcript variant 1, mRNA [NM_001114334] KLA .99 1.00 .90 .89 .99 .99 .92
ATP 1.01 .96 1.00 .79 1.36 1.19 .72
KLA/ATP 1.08 .99 .93 .92 1.18 .90 .56
Rps6kb1
KLA  ATP  ATP+KLA
 NM_028259 ribosomal protein S6 kinase, polypeptide 1 (Rps6kb1), transcript variant 2, mRNA [NM_028259] KLA 1.01 .93 1.07 1.04 .99 .99 .98
ATP 1.09 1.05 1.00 1.01 1.08 1.03 1.03
KLA/ATP 1.07 1.04 .94 .98 1.03 1.05 1.05
Rps6kb2
KLA  ATP  ATP+KLA
 AK090093 kidney CCL-142 RAG cDNA, RIKEN full-length enriched library, clone:G430107K15 product:ribosomal protein S6 kinase, 70kD, polypeptide 2, full insert sequence [AK090093] KLA .97 1.01 .98 .97 .98 1.04 1.07
ATP 1.00 1.08 1.06 1.09 1.11 1.06 1.03
KLA/ATP 1.05 .96 .86 1.03 1.40 1.07 .99
Rps6kb2
KLA  ATP  ATP+KLA
 NM_021485 ribosomal protein S6 kinase, polypeptide 2 (Rps6kb2), mRNA [NM_021485] KLA 1.36 1.40 1.45 1.40 1.63 1.57 1.46
ATP 1.08 1.19 .97 1.15 .90 .99 1.34
KLA/ATP 1.44 1.55 1.09 1.39 1.00 1.12 1.77
Skp1a
KLA  ATP  ATP+KLA
 NM_011543 S-phase kinase-associated protein 1A (Skp1a), mRNA [NM_011543] KLA 1.05 1.00 .92 .92 .88 .89 1.02
ATP .90 .98 1.21 1.43 1.32 1.46 1.09
KLA/ATP .93 1.01 1.11 1.31 1.21 1.27 1.21
Smad1
KLA  ATP  ATP+KLA
 NM_008539 MAD homolog 1 (Drosophila) (Smad1), mRNA [NM_008539] KLA .54 .60 .74 .93 1.36 1.54 1.27
ATP .99 1.02 .81 .87 1.26 .93 .84
KLA/ATP .57 .55 .54 .63 1.04 .97 .88
Smad2
KLA  ATP  ATP+KLA
 NM_010754 MAD homolog 2 (Drosophila) (Smad2), mRNA [NM_010754] KLA 1.05 1.08 1.04 1.17 1.40 1.43 1.59
ATP 1.01 1.02 1.16 1.14 1.15 1.32 1.34
KLA/ATP 1.00 .99 .97 1.09 1.40 1.14 1.40
Smad3
KLA  ATP  ATP+KLA
 NM_016769 MAD homolog 3 (Drosophila) (Smad3), mRNA [NM_016769] KLA .64 .60 .57 .64 .70 1.25 1.52
ATP 1.02 1.02 .84 1.21 2.42 .90 1.19
KLA/ATP .64 .60 .65 .66 1.29 1.26 2.26
Smad4
KLA  ATP  ATP+KLA
 NM_008540 MAD homolog 4 (Drosophila) (Smad4), mRNA [NM_008540] KLA 1.11 1.11 1.13 1.09 1.02 .98 1.08
ATP 1.00 1.04 .92 .76 1.67 1.44 .92
KLA/ATP 1.09 1.01 .87 .89 1.64 1.43 .99
Smad5
KLA  ATP  ATP+KLA
 NM_008541 MAD homolog 5 (Drosophila) (Smad5), mRNA [NM_008541] KLA .62 .59 .53 .53 .59 .71 .76
ATP 1.02 .95 .92 .62 .78 .90 .59
KLA/ATP .59 .59 .57 .46 .75 .88 .52
Smad6
KLA  ATP  ATP+KLA
 NM_008542 MAD homolog 6 (Drosophila) (Smad6), mRNA [NM_008542] KLA .71 .74 .47 .60 .98 2.87 4.17
ATP 1.07 1.07 .80 1.15 2.35 1.34 3.16
KLA/ATP .67 .76 .52 .63 .81 1.31 4.48
Smad7
KLA  ATP  ATP+KLA
 NM_001042660 MAD homolog 7 (Drosophila) (Smad7), mRNA [NM_001042660] KLA .58 .57 .41 .72 .72 1.04 .97
ATP 1.14 1.16 1.84 4.55 2.55 1.97 1.44
KLA/ATP .64 .58 .65 2.41 2.10 1.98 2.69
Smad9
KLA  ATP  ATP+KLA
 AF175408 SMAD8 protein (Smad8) mRNA, complete cds. [AF175408] KLA 1.01 1.01 .90 1.02 1.00 .96 .94
ATP 1.03 1.04 .96 1.03 1.02 1.08 1.09
KLA/ATP .97 .92 1.07 1.00 .99 .94 1.04
Smad9
KLA  ATP  ATP+KLA
 NM_019483 MAD homolog 9 (Drosophila) (Smad9), mRNA [NM_019483] KLA .92 .97 1.07 1.01 1.01 .98 1.04
ATP 1.04 1.02 .95 .97 1.03 .90 .98
KLA/ATP .94 1.07 .94 1.03 1.03 .98 .98
Smurf1
KLA  ATP  ATP+KLA
 NM_001038627 SMAD specific E3 ubiquitin protein ligase 1 (Smurf1), transcript variant 1, mRNA [NM_001038627] KLA 1.94 1.84 1.87 1.68 1.85 2.06 2.12
ATP 1.04 1.10 1.05 1.05 1.43 2.14 2.38
KLA/ATP 1.95 2.05 1.81 1.79 1.55 2.17 3.75
Smurf2
KLA  ATP  ATP+KLA
 NM_025481 SMAD specific E3 ubiquitin protein ligase 2 (Smurf2), mRNA [NM_025481] KLA .66 .66 .71 .75 1.11 1.14 1.16
ATP 1.03 1.10 1.22 .90 1.15 1.09 1.19
KLA/ATP .71 .72 .76 .65 1.04 .96 1.30
Sp1
KLA  ATP  ATP+KLA
 NM_013672 trans-acting transcription factor 1 (Sp1), mRNA [NM_013672] KLA .81 .75 .67 .79 .89 1.00 .84
ATP .96 1.01 1.13 .93 1.30 1.51 .84
KLA/ATP .73 .74 .81 .66 1.38 1.34 1.20
Tfdp1
KLA  ATP  ATP+KLA
 BC058633 transcription factor Dp 1, mRNA (cDNA clone IMAGE:6416171), partial cds [BC058633] KLA .71 .75 .68 .62 .52 .54 .51
ATP .99 1.09 .94 .96 .68 .60 .53
KLA/ATP .76 .75 .58 .61 .45 .57 .36
Tfdp1
KLA  ATP  ATP+KLA
 NM_009361 transcription factor Dp 1 (Tfdp1), mRNA [NM_009361] KLA .70 .71 .65 .55 .48 .52 .50
ATP .97 1.14 .94 1.00 .65 .53 .51
KLA/ATP .66 .71 .52 .55 .38 .48 .33
Tgfb1
KLA  ATP  ATP+KLA
 NM_011577 transforming growth factor, beta 1 (Tgfb1), mRNA [NM_011577] KLA .87 .89 .90 .70 .83 .77 1.12
ATP 1.20 1.41 .80 1.49 1.11 .93 .99
KLA/ATP 1.10 1.20 .53 1.05 .66 .85 .90
Tgfb2
KLA  ATP  ATP+KLA
 NM_009367 transforming growth factor, beta 2 (Tgfb2), mRNA [NM_009367] KLA 1.01 .91 .98 .98 .92 1.19 .96
ATP .99 1.03 1.00 1.02 .99 1.07 .93
KLA/ATP 1.02 .99 1.03 .98 1.04 1.06 .96
Tgfb3
KLA  ATP  ATP+KLA
 NM_009368 transforming growth factor, beta 3 (Tgfb3), mRNA [NM_009368] KLA .67 .64 .58 .56 .49 .52 .61
ATP .90 .92 1.33 1.08 .78 .65 .74
KLA/ATP .58 .60 .74 .61 .76 1.36 1.51
Tgfbr1
KLA  ATP  ATP+KLA
 NM_009370 transforming growth factor, beta receptor I (Tgfbr1), mRNA [NM_009370] KLA .73 .74 .59 .54 .52 .64 .84
ATP .99 1.12 .99 1.16 1.22 .84 .93
KLA/ATP .75 .78 .58 .64 .62 .59 .77
Tgfbr2
KLA  ATP  ATP+KLA
 AK090393 10 days pregnant adult female ovary and uterus cDNA, RIKEN full-length enriched library, clone:G630098D03 product:transforming growth factor, beta receptor II, full insert sequence. [AK090393] KLA .98 .89 1.00 .96 .94 1.00 .92
ATP .99 .99 .90 .94 .93 .96 1.02
KLA/ATP .92 .96 .98 .98 .98 .95 1.01
Tgfbr2
KLA  ATP  ATP+KLA
 NM_009371 transforming growth factor, beta receptor II (Tgfbr2), transcript variant 1, mRNA [NM_009371] KLA .55 .50 .58 .50 .52 .55 .44
ATP .98 .75 .50 .32 .41 .29 .50
KLA/ATP .59 .45 .32 .23 .31 .27 .25
Tgfbr2
KLA  ATP  ATP+KLA
 NM_029575 transforming growth factor, beta receptor II (Tgfbr2), transcript variant 2, mRNA [NM_029575] KLA .95 .93 .99 .95 .88 1.02 .82
ATP .87 .93 .84 .84 .74 .72 1.00
KLA/ATP .89 .85 .83 .85 .76 .80 .79
Thbs1
KLA  ATP  ATP+KLA
 NM_011580 thrombospondin 1 (Thbs1), mRNA [NM_011580] KLA 2.22 2.22 2.74 3.10 4.57 7.17 7.22
ATP 1.16 2.53 8.45 12.26 15.50 43.06 35.83
KLA/ATP 2.46 3.43 8.29 17.50 28.16 46.17 54.67
Tnf
KLA  ATP  ATP+KLA
 NM_013693 tumor necrosis factor (Tnf), mRNA [NM_013693] KLA 13.35 12.76 10.71 9.03 10.64 7.39 8.32
ATP 2.01 2.48 8.27 19.20 9.72 4.09 1.49
KLA/ATP 12.72 15.76 12.73 17.34 5.10 3.61 6.07
Zfyve16
KLA  ATP  ATP+KLA
 NM_173392 zinc finger, FYVE domain containing 16 (Zfyve16), mRNA [NM_173392] KLA 1.04 1.03 1.02 1.05 .99 1.06 1.01
ATP 1.03 1.06 1.00 .76 .86 1.01 .98
KLA/ATP 1.00 1.04 .95 .78 .84 .98 1.10
Zfyve9
KLA  ATP  ATP+KLA
 AK081320 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130005E21 product:unclassifiable, full insert sequence. [AK081320] KLA .99 .99 1.02 .96 1.06 .94 1.06
ATP 1.01 .97 .98 .97 1.06 1.00 1.03
KLA/ATP .97 1.00 .99 1.01 1.20 .97 .96
Zfyve9
KLA  ATP  ATP+KLA
 BC094578 cDNA clone IMAGE:6851752 [BC094578] KLA .94 .98 .89 .92 .88 .93 .87
ATP 1.00 1.10 1.04 .91 .93 1.00 .91
KLA/ATP .93 .93 .88 .92 .86 .86 .90