Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: GnRH signaling pathway (mmu04912)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
Adcy1
KLA  ATP  ATP+KLA
 BC050125 adenylate cyclase 1, mRNA (cDNA clone IMAGE:30015692). [BC050125] KLA 1.05 1.03 .98 1.04 1.05 1.09 1.10
ATP .90 1.02 .99 .97 1.03 .95 1.01
KLA/ATP .99 1.04 .90 .98 .98 1.00 1.03
Adcy1
KLA  ATP  ATP+KLA
 NM_009622 adenylate cyclase 1 (Adcy1), mRNA [NM_009622] KLA 1.07 1.02 1.06 1.07 1.03 1.02 1.01
ATP 1.02 1.04 1.00 .99 .99 .95 .97
KLA/ATP .97 1.05 1.02 1.05 1.01 .98 1.05
Adcy2
KLA  ATP  ATP+KLA
 NM_153534 adenylate cyclase 2 (Adcy2), mRNA [NM_153534] KLA .79 .82 .83 .73 .61 .66 .90
ATP 1.10 1.09 1.02 1.04 .88 .58 .53
KLA/ATP .84 .87 .77 .75 .68 .60 .43
Adcy3
KLA  ATP  ATP+KLA
 NM_138305 adenylate cyclase 3 (Adcy3), mRNA [NM_138305] KLA .84 .84 .83 .78 .66 .55 .49
ATP 1.09 1.05 .89 1.02 .84 .62 1.52
KLA/ATP .93 .87 .75 .85 .66 .83 .77
Adcy4
KLA  ATP  ATP+KLA
 NM_080435 adenylate cyclase 4 (Adcy4), mRNA [NM_080435] KLA 1.05 1.07 .96 1.00 1.04 1.05 1.05
ATP 1.02 1.05 1.02 1.48 1.37 1.08 1.09
KLA/ATP 1.00 1.05 .91 1.19 1.35 1.27 1.08
Adcy5
KLA  ATP  ATP+KLA
 NM_001012765 adenylate cyclase 5 (Adcy5), mRNA [NM_001012765] KLA 1.06 1.00 .97 1.01 1.03 .95 .93
ATP .95 1.08 1.08 1.07 .97 1.03 .97
KLA/ATP .97 .92 1.04 .99 .91 .96 1.04
Adcy6
KLA  ATP  ATP+KLA
 NM_007405 adenylate cyclase 6 (Adcy6), mRNA [NM_007405] KLA 1.10 1.16 1.16 1.09 1.08 1.06 .99
ATP 1.05 .97 1.08 1.12 1.08 1.08 1.04
KLA/ATP 1.14 1.20 1.29 1.30 1.25 1.11 1.07
Adcy7
KLA  ATP  ATP+KLA
 NM_001037724 adenylate cyclase 7 (Adcy7), transcript variant 3, mRNA [NM_001037724] KLA .43 .39 .35 .32 .45 .72 .84
ATP .90 .84 .62 .41 .53 .42 .94
KLA/ATP .39 .34 .23 .17 .41 .34 .67
Adcy7
KLA  ATP  ATP+KLA
 NM_007406 adenylate cyclase 7 (Adcy7), transcript variant 1, mRNA [NM_007406] KLA .51 .52 .48 .41 .59 .81 .99
ATP 1.01 1.02 .62 .52 .53 .38 .98
KLA/ATP .53 .48 .30 .27 .42 .36 .65
Adcy8
KLA  ATP  ATP+KLA
 NM_009623 adenylate cyclase 8 (Adcy8), mRNA [NM_009623] KLA 1.00 1.00 1.07 .97 1.04 .98 1.02
ATP 1.04 1.05 1.14 1.03 .99 1.00 .97
KLA/ATP 1.05 1.04 1.00 1.03 .98 .94 .96
Adcy9
KLA  ATP  ATP+KLA
 NM_009624 adenylate cyclase 9 (Adcy9), mRNA [NM_009624] KLA .18 .15 .13 .15 .17 .19 .33
ATP 1.33 1.16 .97 .98 .62 .56 .86
KLA/ATP .19 .16 .17 .18 .20 .25 .38
Atf4
KLA  ATP  ATP+KLA
 NM_009716 activating transcription factor 4 (Atf4), mRNA [NM_009716] KLA .91 1.06 1.13 1.31 1.92 2.59 3.01
ATP 1.05 1.14 1.34 2.88 4.84 2.36 2.56
KLA/ATP 1.14 1.08 1.17 2.40 3.72 3.54 3.62
Cacna1d
KLA  ATP  ATP+KLA
 NM_001083616 calcium channel, voltage-dependent, L type, alpha 1D subunit (Cacna1d), transcript variant 2, mRNA [NM_001083616] KLA 1.57 1.58 2.50 3.62 4.55 2.93 .99
ATP 1.12 .99 .97 .94 .75 1.71 1.48
KLA/ATP 1.47 1.51 1.82 1.56 1.67 2.93 4.60
Cacna1d
KLA  ATP  ATP+KLA
 NM_028981 calcium channel, voltage-dependent, L type, alpha 1D subunit (Cacna1d), transcript variant 1, mRNA [NM_028981] KLA 1.20 1.26 1.43 1.62 2.07 1.66 1.00
ATP 1.03 1.03 .97 .97 .93 1.20 1.26
KLA/ATP 1.16 1.12 1.10 1.14 1.08 1.44 2.56
Cacna1f
KLA  ATP  ATP+KLA
 NM_019582 calcium channel, voltage-dependent, alpha 1F subunit (Cacna1f), mRNA [NM_019582] KLA 1.03 .98 1.05 1.06 1.00 1.02 1.01
ATP 1.05 1.05 .95 .98 .97 .96 1.01
KLA/ATP 1.01 1.03 .94 1.01 1.01 1.00 .99
Cacna1s
KLA  ATP  ATP+KLA
 NM_001081023 calcium channel, voltage-dependent, L type, alpha 1S subunit (Cacna1s), mRNA [NM_001081023] KLA 1.03 1.01 .96 1.06 1.00 1.00 1.05
ATP 1.01 .98 1.02 1.02 1.05 1.07 1.05
KLA/ATP .99 1.05 1.02 1.05 1.03 1.05 1.00
Calm1
KLA  ATP  ATP+KLA
 NM_009790 calmodulin 1 (Calm1), mRNA [NM_009790] KLA 1.20 1.26 1.30 1.06 1.16 1.09 1.18
ATP 1.07 1.20 1.00 1.29 .99 .64 .58
KLA/ATP 1.31 1.31 .93 1.31 .97 .83 .59
Calm2
KLA  ATP  ATP+KLA
 NM_007589 calmodulin 2 (Calm2), mRNA [NM_007589] KLA .79 .81 .71 .67 .54 .45 .64
ATP .99 1.03 1.04 .93 .82 .52 .76
KLA/ATP .76 .78 .76 .77 .73 .47 .42
Calm3
KLA  ATP  ATP+KLA
 NM_007590 calmodulin 3 (Calm3), mRNA [NM_007590] KLA .95 .96 .93 1.03 1.05 1.08 1.00
ATP .93 .96 .99 .97 .93 .84 .72
KLA/ATP .89 .93 .90 .91 1.02 .98 .70
Calm4
KLA  ATP  ATP+KLA
 NM_020036 calmodulin 4 (Calm4), mRNA [NM_020036] KLA 1.02 .96 1.05 1.00 .99 1.00 1.01
ATP 1.10 1.05 1.03 1.01 .94 .98 .98
KLA/ATP .99 1.12 1.01 1.03 .98 1.07 1.02
Calm5
KLA  ATP  ATP+KLA
 NM_001008706 calmodulin 5 (Calm5), mRNA [NM_001008706] KLA 1.02 1.11 .99 .98 1.07 1.01 1.09
ATP 1.07 1.05 1.04 1.04 1.01 1.04 .99
KLA/ATP 1.00 1.00 .97 1.07 1.00 1.07 .98
Calml3
KLA  ATP  ATP+KLA
 NM_027416 calmodulin-like 3 (Calml3), mRNA [NM_027416] KLA 1.01 .95 1.05 .91 1.01 .98 .89
ATP .91 1.05 1.04 1.01 .93 1.07 .99
KLA/ATP 1.01 .96 .97 .96 .97 .92 .99
Camk2a
KLA  ATP  ATP+KLA
 NM_177407 calcium/calmodulin-dependent protein kinase II alpha (Camk2a), transcript variant 2, mRNA [NM_177407] KLA .98 .97 .98 .95 .97 1.02 .97
ATP .98 1.11 1.02 .89 .94 .89 .82
KLA/ATP .99 .95 1.02 .88 .88 .87 .87
Camk2b
KLA  ATP  ATP+KLA
 NM_007595 calcium/calmodulin-dependent protein kinase II, beta (Camk2b), mRNA [NM_007595] KLA 1.09 1.28 1.42 1.41 1.37 1.24 .68
ATP .94 .87 .95 .91 .67 .44 .48
KLA/ATP 1.16 1.24 1.40 1.13 1.14 .81 .49
Camk2d
KLA  ATP  ATP+KLA
 AK032524 adult male olfactory brain cDNA, RIKEN full-length enriched library, clone:6430579P05 product:calcium/calmodulin-dependent protein kinase II, delta, full insert sequence. [AK032524] KLA 1.31 1.45 1.42 1.21 1.34 1.18 1.16
ATP 1.04 1.29 1.39 1.24 .94 .91 1.22
KLA/ATP 1.46 1.64 1.42 1.24 1.00 .93 1.10
Camk2d
KLA  ATP  ATP+KLA
 NM_001025439 calcium/calmodulin-dependent protein kinase II, delta (Camk2d), transcript variant 1, mRNA [NM_001025439] KLA 1.76 1.75 1.72 1.89 1.47 1.55 1.24
ATP 1.06 1.06 .93 1.01 1.22 .98 2.28
KLA/ATP 1.84 1.78 1.40 1.57 1.07 .60 1.97
Camk2g
KLA  ATP  ATP+KLA
 NM_178597 calcium/calmodulin-dependent protein kinase II gamma (Camk2g), transcript variant 1, mRNA [NM_178597] KLA .23 .24 .23 .44 .70 .73 .70
ATP .91 .85 1.07 .86 .58 .59 .95
KLA/ATP .22 .20 .35 .25 .54 .59 .71
Cdc42
KLA  ATP  ATP+KLA
 NM_009861 cell division cycle 42 homolog (S. cerevisiae) (Cdc42), mRNA [NM_009861] KLA 1.04 1.01 1.02 1.04 1.12 1.21 1.12
ATP 1.07 1.10 1.04 1.06 1.02 .95 1.14
KLA/ATP .94 1.04 1.01 .97 .95 1.02 1.25
Cga
KLA  ATP  ATP+KLA
 NM_009889 glycoprotein hormones, alpha subunit (Cga), mRNA [NM_009889] KLA .98 .95 .95 1.01 1.01 .95 1.01
ATP .96 .89 .84 .90 1.03 .88 .98
KLA/ATP .99 .98 .83 .89 .98 .91 .86
Egfr
KLA  ATP  ATP+KLA
 NM_007912 epidermal growth factor receptor (Egfr), transcript variant 2, mRNA [NM_007912] KLA 1.10 1.07 1.14 1.11 1.08 1.03 .90
ATP .99 1.00 1.04 .98 .97 1.15 1.14
KLA/ATP 1.07 1.10 1.16 1.08 1.01 .97 .94
Egfr
KLA  ATP  ATP+KLA
 NM_207655 epidermal growth factor receptor (Egfr), transcript variant 1, mRNA [NM_207655] KLA 1.57 1.44 1.47 1.31 .96 .92 .76
ATP .97 .93 1.10 1.00 1.41 2.97 .86
KLA/ATP 1.44 1.50 1.61 1.30 1.14 1.21 .82
Elk1
KLA  ATP  ATP+KLA
 AK082260 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230030F12 product:ELK1, member of ETS oncogene family, full insert sequence. [AK082260] KLA 1.02 1.01 1.01 .97 1.00 1.03 1.06
ATP 1.02 1.07 1.06 1.03 1.02 1.02 1.00
KLA/ATP 1.08 .99 .97 1.01 1.02 1.06 .95
Fshb
KLA  ATP  ATP+KLA
 NM_008045 follicle stimulating hormone beta (Fshb), mRNA [NM_008045] KLA 1.05 1.05 1.01 .98 1.05 1.03 1.07
ATP 1.02 1.01 1.02 .94 1.02 1.02 .96
KLA/ATP 1.10 1.03 .99 1.00 1.07 1.06 .98
Gna11
KLA  ATP  ATP+KLA
 NM_010301 guanine nucleotide binding protein, alpha 11 (Gna11), mRNA [NM_010301] KLA .62 .65 .69 .79 .94 1.00 .96
ATP 1.00 .94 .63 .53 .79 1.13 1.22
KLA/ATP .64 .60 .56 .55 .81 1.16 1.18
Gnaq
KLA  ATP  ATP+KLA
 NM_008139 guanine nucleotide binding protein, alpha q polypeptide (Gnaq), mRNA [NM_008139] KLA .82 .82 .69 .64 .60 .55 .55
ATP 1.06 1.02 .87 .67 .50 .66 .57
KLA/ATP .82 .79 .66 .55 .41 .33 .48
Gnas
KLA  ATP  ATP+KLA
 AF107847 neuroendocrine-specific Golgi protein p55 isoform 1 (XLalphas) alternatively spliced mRNA, complete cds. [AF107847] KLA 1.04 .94 1.00 1.05 1.04 .98 1.00
ATP .98 .97 .96 1.00 .99 .98 1.02
KLA/ATP 1.04 1.02 .96 .95 1.01 .96 1.01
Gnas
KLA  ATP  ATP+KLA
 AK017423 10 days neonate head cDNA, RIKEN full-length enriched library, clone:5530400H20 product:novel noncoding RNA overlapping the exon 1A, 1 and 2 of Gnas, full insert sequence. [AK017423] KLA .85 1.08 .97 .92 1.05 1.03 1.08
ATP .99 1.30 2.11 1.73 1.23 1.01 1.02
KLA/ATP .96 1.06 1.58 1.34 1.29 1.05 .91
Gnas
KLA  ATP  ATP+KLA
 NM_001077510 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus (Gnas), transcript variant 8, mRNA [NM_001077510] KLA .99 1.03 .97 .91 1.03 .95 .97
ATP 1.04 1.19 1.15 1.61 1.24 .91 1.00
KLA/ATP 1.06 .97 1.01 1.46 1.04 .85 1.01
Gnas
KLA  ATP  ATP+KLA
 S49980 gb|stimulatory G protein alpha subunit {clone WC-16} [mice, whole cochlea, mRNA Partial, 356 nt]. [S49980] KLA .91 .88 1.03 .87 .90 .84 1.01
ATP 1.16 1.22 1.02 1.55 1.16 .80 .99
KLA/ATP 1.01 1.13 .86 1.12 .97 .85 1.08
Gnrh1
KLA  ATP  ATP+KLA
 NM_008145 gonadotropin releasing hormone 1 (Gnrh1), mRNA [NM_008145] KLA .80 .84 .94 .97 .93 1.04 .97
ATP 1.01 1.10 1.21 1.12 3.15 1.61 .95
KLA/ATP .84 .92 1.03 .93 2.48 1.56 1.23
Gnrhr
KLA  ATP  ATP+KLA
 NM_010323 gonadotropin releasing hormone receptor (Gnrhr), mRNA [NM_010323] KLA 1.01 .98 1.04 1.00 1.01 .96 .99
ATP 1.03 1.00 .98 1.06 1.01 1.00 .99
KLA/ATP 1.05 1.04 1.00 .97 1.00 .98 1.08
Grb2
KLA  ATP  ATP+KLA
 NM_008163 growth factor receptor bound protein 2 (Grb2), mRNA [NM_008163] KLA .92 .88 .90 1.27 1.43 1.22 1.00
ATP 1.02 .83 .51 .42 .92 .70 .57
KLA/ATP .84 .77 .61 .56 1.56 1.49 .52
Grb2
KLA  ATP  ATP+KLA
 U07617 Grb2 adaptor protein (grb2) mRNA, complete cds. [U07617] KLA .83 .80 .95 1.13 1.38 1.36 1.06
ATP .84 .74 .51 .41 .82 .74 .59
KLA/ATP .77 .70 .57 .54 1.49 1.39 .53
Hbegf
KLA  ATP  ATP+KLA
 NM_010415 heparin-binding EGF-like growth factor (Hbegf), mRNA [NM_010415] KLA 4.85 5.22 4.43 2.64 1.67 1.05 .85
ATP 1.16 1.29 9.30 21.54 19.63 14.93 4.45
KLA/ATP 5.32 5.51 13.94 26.41 22.89 13.95 5.50
Hras1
KLA  ATP  ATP+KLA
 NM_008284 Harvey rat sarcoma virus oncogene 1 (Hras1), mRNA [NM_008284] KLA .79 .82 .77 .82 .94 1.03 1.07
ATP 1.01 .95 .69 .83 .79 1.12 1.15
KLA/ATP .84 .77 .61 .65 .82 1.00 1.05
Itpr1
KLA  ATP  ATP+KLA
 NM_010585 inositol 1,4,5-triphosphate receptor 1 (Itpr1), mRNA [NM_010585] KLA 3.66 3.69 6.74 8.11 7.08 4.40 1.22
ATP 1.08 .95 1.19 .94 1.09 1.00 .68
KLA/ATP 3.48 3.58 5.86 6.03 4.01 2.31 .97
Itpr2
KLA  ATP  ATP+KLA
 NM_019923 inositol 1,4,5-triphosphate receptor 2 (Itpr2), transcript variant 1, mRNA [NM_019923] KLA 1.41 1.38 1.43 1.42 1.30 1.07 1.01
ATP 1.00 1.00 .97 .97 1.07 1.15 1.06
KLA/ATP 1.39 1.48 1.64 1.42 1.07 .83 .95
Itpr3
KLA  ATP  ATP+KLA
 NM_080553 inositol 1,4,5-triphosphate receptor 3 (Itpr3), mRNA [NM_080553] KLA .55 .51 .45 .41 .34 .34 .45
ATP 1.01 .92 1.02 .57 .46 .34 1.22
KLA/ATP .56 .48 .48 .29 .33 .27 .65
Jun
KLA  ATP  ATP+KLA
 NM_010591 Jun oncogene (Jun), mRNA [NM_010591] KLA 1.08 .96 1.09 1.09 .75 .88 .81
ATP 1.26 1.48 4.45 8.73 4.02 1.16 1.99
KLA/ATP 1.12 1.38 3.52 5.17 3.32 .49 1.42
Kras
KLA  ATP  ATP+KLA
 NM_021284 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Kras), mRNA [NM_021284] KLA .53 .49 .40 .42 .49 .95 1.05
ATP .98 1.01 1.16 1.17 1.39 1.29 1.74
KLA/ATP .50 .47 .50 .56 1.00 1.24 1.58
Lhb
KLA  ATP  ATP+KLA
 AK138425 adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230101A12 product:luteinizing hormone beta, full insert sequence [AK138425] KLA 1.06 1.01 1.02 .98 1.00 1.07 .91
ATP 1.02 1.04 .91 .96 .90 1.05 .95
KLA/ATP .98 .96 1.01 1.03 1.04 1.00 1.09
Lhb
KLA  ATP  ATP+KLA
 NM_008497 luteinizing hormone beta (Lhb), mRNA [NM_008497] KLA 1.16 1.26 1.24 1.20 1.29 1.29 1.23
ATP 1.01 1.01 1.12 1.19 1.22 1.21 1.23
KLA/ATP 1.12 1.12 1.33 1.53 1.47 1.42 1.44
Map2k1
KLA  ATP  ATP+KLA
 NM_008927 mitogen-activated protein kinase kinase 1 (Map2k1), mRNA [NM_008927] KLA 1.82 2.00 2.31 2.03 2.51 2.20 1.51
ATP .99 1.14 .81 .87 .90 1.57 1.11
KLA/ATP 1.90 2.03 1.50 1.93 1.63 2.03 2.06
Map2k2
KLA  ATP  ATP+KLA
 NM_023138 mitogen-activated protein kinase kinase 2 (Map2k2), mRNA [NM_023138] KLA .96 1.01 1.09 .99 1.11 1.15 1.42
ATP 1.07 1.05 .74 .86 1.04 1.16 1.21
KLA/ATP 1.14 1.03 .68 .78 .85 1.01 1.20
Map2k3
KLA  ATP  ATP+KLA
 NM_008928 mitogen-activated protein kinase kinase 3 (Map2k3), mRNA [NM_008928] KLA .88 .88 .73 .65 .99 1.34 .92
ATP 1.04 1.09 .89 1.62 1.93 1.75 1.17
KLA/ATP 1.00 .92 .66 1.21 1.80 2.24 2.10
Map2k4
KLA  ATP  ATP+KLA
 NM_009157 mitogen-activated protein kinase kinase 4 (Map2k4), mRNA [NM_009157] KLA 3.67 3.75 4.23 3.90 3.30 1.87 1.12
ATP 1.05 1.11 1.04 .93 1.16 2.62 1.02
KLA/ATP 3.70 4.13 3.27 4.13 2.98 3.03 1.82
Map2k6
KLA  ATP  ATP+KLA
 NM_011943 mitogen-activated protein kinase kinase 6 (Map2k6), mRNA [NM_011943] KLA .68 .67 .64 .67 .62 .59 .61
ATP 1.02 1.12 1.04 1.10 .79 .61 .61
KLA/ATP .73 .69 .71 .74 .66 .62 .98
Map2k7
KLA  ATP  ATP+KLA
 BC070467 mitogen activated protein kinase kinase 7, mRNA (cDNA clone MGC:96654 IMAGE:30615302), complete cds [BC070467] KLA .77 .79 .88 .77 .97 .96 1.27
ATP 1.11 1.26 .93 1.19 1.13 1.45 1.16
KLA/ATP .89 .88 .59 .89 .86 1.32 1.28
Map2k7
KLA  ATP  ATP+KLA
 NM_001042557 mitogen-activated protein kinase kinase 7 (Map2k7), transcript variant 1, mRNA [NM_001042557] KLA .96 .95 1.02 .96 .95 1.09 1.19
ATP 1.02 1.07 .88 .97 .93 1.10 1.17
KLA/ATP 1.01 .99 .80 .87 .76 1.21 1.16
Map3k1
KLA  ATP  ATP+KLA
 NM_011945 mitogen-activated protein kinase kinase kinase 1 (Map3k1), mRNA [NM_011945] KLA .30 .25 .37 .56 .68 1.07 .85
ATP .88 .86 1.26 1.04 1.07 .77 .78
KLA/ATP .28 .24 .59 .99 1.49 .97 1.24
Map3k2
KLA  ATP  ATP+KLA
 NM_011946 mitogen-activated protein kinase kinase kinase 2 (Map3k2), mRNA [NM_011946] KLA .80 .79 .74 .79 .93 1.00 1.09
ATP .99 .97 1.05 1.13 1.79 1.27 1.14
KLA/ATP .81 .76 .77 .84 1.39 1.29 1.26
Map3k3
KLA  ATP  ATP+KLA
 NM_011947 mitogen-activated protein kinase kinase kinase 3 (Map3k3), mRNA [NM_011947] KLA .60 .63 .60 .58 .81 1.03 1.26
ATP .97 .91 .55 .58 .71 .81 .99
KLA/ATP .68 .57 .42 .53 .61 .85 1.23
Map3k4
KLA  ATP  ATP+KLA
 AK035823 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630008E23 product:mitogen activated protein kinase kinase kinase 4, full insert sequence. [AK035823] KLA 1.04 .92 1.04 .92 .96 .98 1.01
ATP 1.00 .95 .99 .99 1.01 .95 1.01
KLA/ATP .99 1.06 .94 1.02 1.03 1.00 .97
Map3k4
KLA  ATP  ATP+KLA
 NM_011948 mitogen-activated protein kinase kinase kinase 4 (Map3k4), mRNA [NM_011948] KLA .56 .57 .58 .66 .81 .94 .99
ATP .97 .93 1.13 .98 .65 .60 .95
KLA/ATP .54 .54 .64 .61 .69 .70 .91
Mapk1
KLA  ATP  ATP+KLA
 NM_001038663 mitogen-activated protein kinase 1 (Mapk1), transcript variant 2, mRNA [NM_001038663] KLA .97 1.03 .93 .86 .79 1.01 1.04
ATP .96 1.18 1.01 1.13 .84 1.04 1.16
KLA/ATP .99 .99 .84 .87 .63 .96 1.26
Mapk1
KLA  ATP  ATP+KLA
 NM_011949 mitogen-activated protein kinase 1 (Mapk1), transcript variant 1, mRNA [NM_011949] KLA .88 .80 .80 .73 .75 .76 .65
ATP .97 .96 1.06 .88 .90 .68 .48
KLA/ATP .82 .81 .78 .65 .64 .64 .45
Mapk10
KLA  ATP  ATP+KLA
 AK076990 adult male testis cDNA, RIKEN full-length enriched library, clone:4930597C01 product:mitogen activated protein kinase 10, full insert sequence. [AK076990] KLA 1.03 1.05 .98 1.04 .94 .95 1.02
ATP 1.00 .99 1.06 .97 1.01 .96 .99
KLA/ATP 1.07 1.01 .95 1.05 .82 .95 .87
Mapk10
KLA  ATP  ATP+KLA
 NM_009158 mitogen-activated protein kinase 10 (Mapk10), transcript variant 1, mRNA [NM_009158] KLA .95 1.00 .97 1.01 .99 1.01 .95
ATP 1.01 1.02 .98 1.01 1.04 1.01 .99
KLA/ATP 1.05 .99 1.01 .98 .92 .97 .98
Mapk11
KLA  ATP  ATP+KLA
 NM_011161 mitogen-activated protein kinase 11 (Mapk11), mRNA [NM_011161] KLA 1.28 1.30 1.41 1.46 1.58 1.29 .98
ATP .96 .95 .89 .82 .79 1.09 .85
KLA/ATP 1.44 1.42 1.32 1.23 1.23 .74 .66
Mapk12
KLA  ATP  ATP+KLA
 NM_013871 mitogen-activated protein kinase 12 (Mapk12), mRNA [NM_013871] KLA .94 .86 .87 .81 .77 .68 .49
ATP .97 .83 .92 .90 .86 .90 .51
KLA/ATP .91 .89 .88 .85 1.12 1.14 .53
Mapk13
KLA  ATP  ATP+KLA
 NM_011950 mitogen-activated protein kinase 13 (Mapk13), mRNA [NM_011950] KLA 1.22 1.21 1.35 1.26 1.24 1.13 1.01
ATP 1.08 1.00 1.20 1.20 1.13 1.22 1.39
KLA/ATP 1.22 1.27 1.30 1.30 1.21 1.11 1.47
Mapk14
KLA  ATP  ATP+KLA
 NM_011951 mitogen-activated protein kinase 14 (Mapk14), mRNA [NM_011951] KLA .70 .70 .62 .54 .67 .88 1.11
ATP 1.03 .98 .87 .69 .48 .78 .66
KLA/ATP .74 .68 .52 .46 .38 .45 .62
Mapk3
KLA  ATP  ATP+KLA
 NM_011952 mitogen-activated protein kinase 3 (Mapk3), mRNA [NM_011952] KLA .81 .85 .88 .72 .79 .73 .90
ATP 1.13 1.30 .92 1.48 1.08 .68 1.03
KLA/ATP 1.01 1.01 .66 1.13 .77 .77 1.16
Mapk7
KLA  ATP  ATP+KLA
 NM_011841 mitogen-activated protein kinase 7 (Mapk7), mRNA [NM_011841] KLA .46 .43 .53 .80 1.03 1.38 1.55
ATP .96 .80 .84 .62 1.76 2.01 1.67
KLA/ATP .39 .40 .47 .50 2.55 1.93 2.48
Mapk8
KLA  ATP  ATP+KLA
 AK162915 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330031O19 product:mitogen activated protein kinase 8, full insert sequence [AK162915] KLA .94 .86 .80 .83 .77 .85 .83
ATP 1.08 1.12 .94 .80 .83 .71 .75
KLA/ATP .83 .81 .80 .74 .74 .75 .67
Mapk8
KLA  ATP  ATP+KLA
 AK163829 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130070A06 product:mitogen activated protein kinase 8, full insert sequence [AK163829] KLA .65 .61 .66 .70 .90 1.02 1.03
ATP .99 .94 1.68 1.44 1.75 1.84 1.10
KLA/ATP .63 .67 1.11 1.00 2.01 1.68 1.15
Mapk8
KLA  ATP  ATP+KLA
 NM_016700 mitogen-activated protein kinase 8 (Mapk8), mRNA [NM_016700] KLA .96 1.00 .94 .96 .94 .99 1.04
ATP 1.01 1.05 1.01 .99 1.03 .98 1.02
KLA/ATP .96 .97 .96 .97 .93 .94 .96
Mapk9
KLA  ATP  ATP+KLA
 NM_016961 mitogen-activated protein kinase 9 (Mapk9), transcript variant 2, mRNA [NM_016961] KLA 1.28 1.37 1.59 1.60 1.61 1.43 1.38
ATP 1.03 .99 .74 .71 .79 1.20 1.01
KLA/ATP 1.53 1.30 1.07 .99 .83 1.10 1.40
Mapk9
KLA  ATP  ATP+KLA
 NM_207692 mitogen-activated protein kinase 9 (Mapk9), transcript variant 1, mRNA [NM_207692] KLA 1.39 1.53 1.69 1.69 1.55 1.44 1.51
ATP .95 .92 .75 .85 .70 1.46 1.17
KLA/ATP 1.37 1.35 .99 1.18 .91 1.22 1.62
Mm.13153
0
KLA  ATP  ATP+KLA
 161086915 Unknown KLA 1.00 1.07 1.14 1.08 .97 1.00 .93
ATP 1.04 .99 1.00 .95 .99 1.02 .90
KLA/ATP 1.08 1.18 1.14 1.16 1.04 1.06 1.08
Mm.27970
KLA  ATP  ATP+KLA
 13994135 Unknown KLA 1.06 1.11 1.16 1.07 1.11 1.08 .95
ATP 1.02 1.09 1.05 1.05 .94 1.16 1.32
KLA/ATP 1.10 1.19 1.11 1.04 1.08 1.02 1.33
Mm.28968
1
KLA  ATP  ATP+KLA
 6754177 Unknown KLA 5.70 5.98 5.26 3.13 1.73 .87 .76
ATP 1.12 1.23 10.71 22.34 24.13 18.42 4.28
KLA/ATP 5.68 6.39 18.15 29.48 26.96 19.85 6.17
Mm.33050
7
KLA  ATP  ATP+KLA
 67906182 Unknown KLA .94 .98 .99 1.03 1.05 1.07 .98
ATP .95 1.02 .97 .98 .99 1.05 1.02
KLA/ATP 1.02 1.05 1.01 1.03 .99 .98 .97
Mm.35830
9
KLA  ATP  ATP+KLA
 158517802 Unknown KLA .63 .61 .71 .69 .91 1.05 .78
ATP 1.00 .94 1.06 .83 5.04 3.12 .78
KLA/ATP .62 .59 .86 .69 4.90 2.07 1.10
Mm.41137
KLA  ATP  ATP+KLA
 148747308 Unknown KLA 1.03 1.00 .95 .92 1.04 .98 .96
ATP 1.02 .98 .98 .90 .95 .92 1.07
KLA/ATP .91 .89 1.01 .95 1.00 .96 .99
Mm.41292
2
KLA  ATP  ATP+KLA
 145966829 Unknown KLA 3.65 3.76 3.75 3.79 3.42 1.75 1.10
ATP 1.11 1.17 1.04 .90 1.37 2.90 1.00
KLA/ATP 3.31 3.97 3.38 3.84 3.04 3.31 2.09
Mm.44160
1
KLA  ATP  ATP+KLA
 145966786 Unknown KLA 1.08 .94 1.01 .97 .79 .78 .71
ATP 1.09 .92 1.10 .75 .65 .92 .69
KLA/ATP 1.01 .92 1.16 .81 .69 .56 .63
Mm.45825
9
KLA  ATP  ATP+KLA
 116292181 Unknown KLA .84 .86 .91 .85 .98 .98 1.00
ATP 1.05 1.06 .94 .95 1.00 .89 .89
KLA/ATP .92 .84 .87 .93 .91 .92 .82
Mmp14
KLA  ATP  ATP+KLA
 NM_008608 matrix metallopeptidase 14 (membrane-inserted) (Mmp14), mRNA [NM_008608] KLA 35.40 35.40 32.92 45.56 49.47 56.29 43.99
ATP 1.01 1.01 1.36 1.97 4.97 15.97 19.45
KLA/ATP 33.50 33.70 42.96 38.89 35.59 38.08 57.15
Mmp2
KLA  ATP  ATP+KLA
 NM_008610 matrix metallopeptidase 2 (Mmp2), mRNA [NM_008610] KLA 1.12 1.24 1.48 1.26 1.44 1.19 1.09
ATP 1.05 1.01 1.07 1.08 .93 1.01 1.14
KLA/ATP 1.23 1.26 1.16 1.15 .95 1.11 1.04
Nras
KLA  ATP  ATP+KLA
 NM_010937 neuroblastoma ras oncogene (Nras), mRNA [NM_010937] KLA 1.20 1.22 1.27 1.20 1.09 .91 .84
ATP .98 .91 .69 .61 .59 .67 .78
KLA/ATP 1.22 1.14 .97 .79 .73 .61 .72
Pla2g4a
KLA  ATP  ATP+KLA
 NM_008869 phospholipase A2, group IVA (cytosolic, calcium-dependent) (Pla2g4a), mRNA [NM_008869] KLA 3.93 4.49 4.86 6.40 6.44 3.10 1.68
ATP 1.13 1.36 1.27 1.30 1.02 5.37 1.47
KLA/ATP 3.64 4.45 4.76 7.11 2.96 4.08 2.60
Pla2g4b
KLA  ATP  ATP+KLA
 NM_145378 phospholipase A2, group IVB (cytosolic) (Pla2g4b), mRNA [NM_145378] KLA 1.09 1.18 .95 1.01 .97 .97 .77
ATP 1.05 1.14 1.28 .94 .88 1.18 .70
KLA/ATP 1.23 1.43 1.21 1.02 1.15 1.16 .78
Pla2g4c
KLA  ATP  ATP+KLA
 AK145339 1 cell embryo 1 cell cDNA, RIKEN full-length enriched library, clone:I0C0013F18 product:weakly similar to Cytosolic phospholipase A2 gamma [Homo sapiens], full insert sequence [AK145339] KLA 1.09 1.21 1.33 1.17 1.26 1.30 1.05
ATP .97 1.06 1.00 .98 .98 .98 1.05
KLA/ATP 1.19 1.16 1.18 1.13 1.04 1.02 1.06
Pla2g4c
KLA  ATP  ATP+KLA
 NM_001004762 phospholipase A2, group IVC (cytosolic, calcium-independent) (Pla2g4c), mRNA [NM_001004762] KLA .93 1.00 .94 .93 .94 .94 .96
ATP .98 .96 1.13 .97 .99 .89 .96
KLA/ATP 1.01 1.01 1.07 1.01 .94 1.01 .92
Pla2g4e
KLA  ATP  ATP+KLA
 AK049063 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230096D22 product:hypothetical Lysophospholipase catalytic domain containing protein, full insert sequence. [AK049063] KLA 1.03 1.09 1.01 1.01 1.06 .94 1.05
ATP 1.03 1.00 1.06 1.01 .96 1.05 1.05
KLA/ATP .98 1.00 1.01 .98 1.03 .95 1.01
Pla2g4e
KLA  ATP  ATP+KLA
 NM_177845 phospholipase A2, group IVE (Pla2g4e), mRNA [NM_177845] KLA .97 .95 1.01 .97 1.02 1.03 1.05
ATP .98 .99 1.00 1.10 .98 1.00 1.02
KLA/ATP 1.05 .93 .96 1.03 1.08 1.05 .99
Pla2g4f
KLA  ATP  ATP+KLA
 NM_001024145 phospholipase A2, group IVF (Pla2g4f), mRNA [NM_001024145] KLA 1.08 .99 1.04 1.02 1.04 .98 1.01
ATP .99 1.04 .99 1.03 1.12 1.01 1.25
KLA/ATP .97 1.04 1.10 1.06 1.04 1.03 1.03
Plcb1
KLA  ATP  ATP+KLA
 AK129166 mRNA for mKIAA0581 protein [AK129166] KLA 1.02 .98 .91 .91 .92 .95 .89
ATP 1.03 1.02 1.02 1.01 .90 1.02 1.04
KLA/ATP .98 .97 .91 .93 .92 1.01 1.16
Plcb1
KLA  ATP  ATP+KLA
 NM_019677 phospholipase C, beta 1 (Plcb1), mRNA [NM_019677] KLA .99 .94 .95 .97 .93 .92 .91
ATP 1.00 .96 .99 .95 .99 1.03 .98
KLA/ATP .93 .96 .94 .93 .87 1.00 1.06
Plcb2
KLA  ATP  ATP+KLA
 NM_177568 phospholipase C, beta 2 (Plcb2), mRNA [NM_177568] KLA .70 .68 .64 .67 .65 .76 .88
ATP .95 .94 1.04 .94 .72 .57 1.19
KLA/ATP .69 .68 .72 .63 .65 .55 .70
Plcb3
KLA  ATP  ATP+KLA
 NM_008874 phospholipase C, beta 3 (Plcb3), mRNA [NM_008874] KLA 1.72 1.78 1.82 1.65 1.67 1.44 1.21
ATP .97 1.04 .81 .87 .78 .88 .94
KLA/ATP 1.69 1.89 1.44 1.66 1.12 .73 .93
Plcb4
KLA  ATP  ATP+KLA
 AK082509 0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230058B11 product:unclassifiable, full insert sequence. [AK082509] KLA 1.06 1.03 .97 .98 1.02 1.01 .99
ATP .99 1.07 1.09 .95 .97 .97 1.02
KLA/ATP .98 1.00 1.03 .96 1.02 .91 .98
Plcb4
KLA  ATP  ATP+KLA
 NM_013829 phospholipase C, beta 4 (Plcb4), mRNA [NM_013829] KLA .88 .94 .81 .82 .81 .86 1.01
ATP 1.00 1.01 .92 .93 .88 .85 .89
KLA/ATP .97 .94 .78 .80 .78 .86 .97
Pld1
KLA  ATP  ATP+KLA
 NM_008875 phospholipase D1 (Pld1), mRNA [NM_008875] KLA .71 .73 .67 .73 .88 .96 1.25
ATP .99 .88 .73 .68 .45 1.23 1.12
KLA/ATP .70 .67 .58 .59 .48 .91 1.48
Pld2
KLA  ATP  ATP+KLA
 NM_008876 phospholipase D2 (Pld2), mRNA [NM_008876] KLA .51 .54 .48 .51 .73 .79 1.02
ATP 1.06 1.10 .88 1.03 1.04 1.29 1.00
KLA/ATP .63 .52 .40 .57 .65 1.03 1.35
Prkaca
KLA  ATP  ATP+KLA
 NM_008854 protein kinase, cAMP dependent, catalytic, alpha (Prkaca), mRNA [NM_008854] KLA .71 .74 .72 .70 .72 .84 .85
ATP 1.05 .98 .89 .92 .76 .60 1.02
KLA/ATP .79 .74 .55 .65 .60 .65 .93
Prkacb
KLA  ATP  ATP+KLA
 NM_011100 protein kinase, cAMP dependent, catalytic, beta (Prkacb), mRNA [NM_011100] KLA .69 .70 .66 .58 .51 .55 .59
ATP 1.02 1.19 .97 1.01 .69 .38 .56
KLA/ATP .72 .73 .57 .62 .47 .41 .45
Prkca
KLA  ATP  ATP+KLA
 NM_011101 protein kinase C, alpha (Prkca), mRNA [NM_011101] KLA 1.00 .96 .94 .95 .95 .89 .96
ATP 1.00 1.03 .91 .94 .82 .87 1.13
KLA/ATP 1.02 .95 .91 .86 .78 .84 .94
Prkcb1
KLA  ATP  ATP+KLA
 NM_008855 protein kinase C, beta 1 (Prkcb1), mRNA [NM_008855] KLA .92 .95 .93 .78 .77 1.08 1.83
ATP 1.03 1.12 1.09 1.23 .90 2.08 .96
KLA/ATP .98 .99 .82 .89 .62 1.01 1.08
Prkcd
KLA  ATP  ATP+KLA
 NM_011103 protein kinase C, delta (Prkcd), mRNA [NM_011103] KLA 1.72 1.84 1.90 1.68 2.01 1.61 1.64
ATP 1.00 1.03 .68 .81 1.38 1.26 .98
KLA/ATP 1.77 1.79 1.16 1.19 1.33 1.25 1.56
Prkx
KLA  ATP  ATP+KLA
 NM_016979 protein kinase, X-linked (Prkx), mRNA [NM_016979] KLA 3.61 3.79 4.67 4.66 4.85 4.19 1.43
ATP .98 .90 .63 .61 1.12 1.90 1.29
KLA/ATP 3.56 3.36 2.62 2.06 2.26 2.87 2.31
Ptk2b
KLA  ATP  ATP+KLA
 NM_172498 PTK2 protein tyrosine kinase 2 beta (Ptk2b), mRNA [NM_172498] KLA 1.34 1.39 1.78 1.70 2.36 2.26 1.77
ATP 1.08 1.21 .59 .69 .65 .71 1.17
KLA/ATP 1.41 1.55 1.07 1.33 1.07 1.24 1.80
Raf1
KLA  ATP  ATP+KLA
 AK036317 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630056E02 product:v-raf-1 leukemia viral oncogene 1, full insert sequence. [AK036317] KLA 1.47 1.34 1.55 1.29 1.59 1.32 1.46
ATP 1.05 .98 .54 .63 3.32 2.07 1.01
KLA/ATP 1.57 1.33 .79 .96 2.26 1.38 1.35
Raf1
KLA  ATP  ATP+KLA
 NM_029780 v-raf-leukemia viral oncogene 1 (Raf1), mRNA [NM_029780] KLA 1.65 1.64 1.93 1.77 1.77 1.72 1.81
ATP .95 .96 .83 .80 2.22 2.92 1.19
KLA/ATP 1.68 1.64 1.39 1.32 1.85 2.50 2.06
Sos1
KLA  ATP  ATP+KLA
 NM_009231 Son of sevenless homolog 1 (Drosophila) (Sos1), mRNA [NM_009231] KLA 2.36 2.40 3.42 3.15 2.78 1.81 1.71
ATP .99 1.00 .99 1.15 1.14 1.25 1.24
KLA/ATP 2.41 2.26 1.95 2.44 1.47 1.66 1.37
Sos2
KLA  ATP  ATP+KLA
 XM_127051 gb|PREDICTED: Mus musculus Son of sevenless homolog 2 (Drosophila) (Sos2), mRNA [XM_127051] KLA .81 .77 .79 .92 1.04 1.06 1.20
ATP 1.00 1.00 1.09 .79 .68 .81 .94
KLA/ATP .77 .69 .71 .60 .64 .77 1.07
Src
KLA  ATP  ATP+KLA
 NM_009271 Rous sarcoma oncogene (Src), transcript variant 1, mRNA [NM_009271] KLA 6.99 7.23 7.54 5.99 5.34 3.39 3.00
ATP 1.02 1.06 1.06 2.08 4.41 5.03 3.97
KLA/ATP 7.44 7.51 5.48 6.24 4.86 5.86 7.90