Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Hepatitis C (mmu05160)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
4930468A
15Rik
KLA  ATP  ATP+KLA
 AK015525 adult male testis cDNA, RIKEN full-length enriched library, clone:4930468A15 product:hypothetical protein, full insert sequence [AK015525] KLA .97 1.00 1.03 .98 1.02 1.01 1.02
ATP 1.03 .97 1.05 1.02 .99 .98 .98
KLA/ATP 1.01 1.00 .97 1.01 .95 .98 .96
Akt1
KLA  ATP  ATP+KLA
 NM_009652 thymoma viral proto-oncogene 1 (Akt1), mRNA [NM_009652] KLA .80 .80 .75 .75 .71 .70 .82
ATP 1.00 1.02 .76 .85 .76 .68 .84
KLA/ATP .82 .80 .64 .68 .67 .61 .72
Akt2
KLA  ATP  ATP+KLA
 NM_007434 thymoma viral proto-oncogene 2 (Akt2), transcript variant 2, mRNA [NM_007434] KLA 1.45 1.49 1.81 1.61 1.83 1.17 .92
ATP 1.12 1.12 1.00 1.28 1.20 .94 1.06
KLA/ATP 1.48 1.70 1.69 1.58 1.57 1.32 1.27
Akt3
KLA  ATP  ATP+KLA
 NM_011785 thymoma viral proto-oncogene 3 (Akt3), mRNA [NM_011785] KLA 3.42 3.45 5.31 5.16 4.65 3.80 2.12
ATP 1.12 1.22 1.10 1.37 1.02 1.11 1.56
KLA/ATP 3.72 4.17 4.62 4.64 2.74 2.05 3.82
Araf
KLA  ATP  ATP+KLA
 NM_009703 v-raf murine sarcoma 3611 viral oncogene homolog (Araf), mRNA [NM_009703] KLA .87 .80 .89 .93 1.10 1.19 1.16
ATP 1.09 1.11 1.19 1.18 .78 .53 1.18
KLA/ATP 1.00 .95 .99 .93 .63 .55 1.27
BB229853
KLA  ATP  ATP+KLA
 BB229853 gb|BB229853 RIKEN full-length enriched, 3 days neonate thymus Mus musculus cDNA clone A630023O21 3. [BB229853] KLA 6.32 5.94 6.13 6.41 7.39 12.33 6.08
ATP .39 .24 .33 .38 1.18 5.75 2.85
KLA/ATP 2.27 2.02 3.25 4.04 7.11 10.22 13.93
Bad
KLA  ATP  ATP+KLA
 AK029400 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4833429M11 product:Bcl-associated death promoter, full insert sequence. [AK029400] KLA 1.15 1.22 1.26 1.31 1.40 1.67 1.59
ATP .95 1.06 1.12 1.06 .78 .89 1.27
KLA/ATP 1.25 1.39 1.33 1.29 1.11 .91 1.38
Braf
KLA  ATP  ATP+KLA
 NM_139294 Braf transforming gene (Braf), mRNA [NM_139294] KLA 1.52 1.57 1.55 1.33 1.83 1.52 1.60
ATP 1.08 1.17 1.02 1.37 .95 1.15 .95
KLA/ATP 1.64 1.69 1.39 1.51 1.04 1.31 1.26
Cd81
KLA  ATP  ATP+KLA
 NM_133655 CD 81 antigen (Cd81), mRNA [NM_133655] KLA .80 .79 .78 .74 .59 .45 .25
ATP .89 .74 .63 .54 .45 .57 .47
KLA/ATP .75 .67 .65 .51 .45 .39 .41
Cdkn1a
KLA  ATP  ATP+KLA
 NM_007669 cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a), transcript variant 1, mRNA [NM_007669] KLA 4.72 4.90 4.96 3.73 2.11 1.14 1.02
ATP 1.14 1.52 .95 1.69 1.47 2.21 .50
KLA/ATP 5.99 7.08 3.86 6.37 3.00 2.55 2.05
Chuk
KLA  ATP  ATP+KLA
 NM_007700 conserved helix-loop-helix ubiquitous kinase (Chuk), mRNA [NM_007700] KLA 1.32 1.42 1.41 1.17 1.32 1.22 1.40
ATP 1.22 1.30 1.18 .97 1.02 1.00 1.37
KLA/ATP 1.56 1.61 1.21 1.09 .83 .84 1.17
Cldn1
KLA  ATP  ATP+KLA
 NM_016674 claudin 1 (Cldn1), mRNA [NM_016674] KLA .97 1.02 1.02 1.05 1.05 .99 1.07
ATP 1.02 .94 1.03 1.08 1.05 .98 1.02
KLA/ATP 1.03 1.02 1.00 1.00 1.17 1.01 1.03
Cldn10
KLA  ATP  ATP+KLA
 NM_021386 claudin 10 (Cldn10), transcript variant 2, mRNA [NM_021386] KLA 1.06 1.05 1.04 1.12 1.08 1.05 1.04
ATP 1.07 .97 .98 1.06 1.00 1.01 .97
KLA/ATP 1.01 1.06 .86 .98 1.03 1.04 1.09
Cldn11
KLA  ATP  ATP+KLA
 NM_008770 claudin 11 (Cldn11), mRNA [NM_008770] KLA 1.05 1.10 1.04 .99 .97 .99 .97
ATP 1.03 1.01 1.08 3.05 1.24 1.11 1.07
KLA/ATP 1.02 .96 1.42 2.53 1.09 1.02 1.03
Cldn13
KLA  ATP  ATP+KLA
 NM_020504 claudin 13 (Cldn13), mRNA [NM_020504] KLA 1.02 1.00 1.02 .97 1.01 .98 .99
ATP .92 .96 1.05 .96 1.02 1.04 1.04
KLA/ATP .93 .94 1.10 1.06 1.00 .93 1.03
Cldn14
KLA  ATP  ATP+KLA
 NM_019500 claudin 14 (Cldn14), mRNA [NM_019500] KLA 1.03 1.12 1.14 1.08 1.09 1.16 1.08
ATP 1.03 .99 1.12 1.04 1.07 1.10 1.06
KLA/ATP 1.07 1.14 1.21 1.12 1.07 1.10 1.08
Cldn15
KLA  ATP  ATP+KLA
 NM_021719 claudin 15 (Cldn15), mRNA [NM_021719] KLA 1.01 1.07 1.04 1.09 1.06 1.11 .98
ATP 1.17 1.26 1.27 1.08 1.24 1.11 1.05
KLA/ATP 1.25 1.31 1.19 1.22 1.70 1.26 1.03
Cldn16
KLA  ATP  ATP+KLA
 NM_053241 claudin 16 (Cldn16), mRNA [NM_053241] KLA 1.08 .98 1.02 1.00 1.06 1.05 1.00
ATP 1.01 1.05 1.01 1.12 1.05 .98 .99
KLA/ATP .98 .95 1.04 1.05 1.02 1.15 1.01
Cldn17
KLA  ATP  ATP+KLA
 NM_181490 claudin 17 (Cldn17), mRNA [NM_181490] KLA .99 1.05 1.01 1.00 .97 .99 1.01
ATP .95 .98 1.06 1.05 .97 1.00 1.00
KLA/ATP 1.04 1.00 .95 1.05 .96 1.02 1.11
Cldn18
KLA  ATP  ATP+KLA
 NM_019815 claudin 18 (Cldn18), mRNA [NM_019815] KLA .99 1.06 .99 .99 1.03 1.13 1.11
ATP .96 1.00 1.10 .98 .95 .98 1.07
KLA/ATP 1.07 .95 1.05 1.07 1.11 1.06 1.02
Cldn19
KLA  ATP  ATP+KLA
 NM_001038590 claudin 19 (Cldn19), transcript variant 1, mRNA [NM_001038590] KLA 1.06 .92 1.01 1.01 1.03 .96 1.00
ATP 1.00 .97 1.05 .93 .95 .91 1.01
KLA/ATP .93 .99 .96 .93 .91 .92 .93
Cldn19
KLA  ATP  ATP+KLA
 NM_153105 claudin 19 (Cldn19), transcript variant 2, mRNA [NM_153105] KLA .97 1.01 1.02 1.05 1.06 .96 1.09
ATP 1.04 .98 1.08 1.02 .98 1.00 .96
KLA/ATP 1.02 1.03 1.03 1.02 1.00 1.02 1.03
Cldn2
KLA  ATP  ATP+KLA
 NM_016675 claudin 2 (Cldn2), mRNA [NM_016675] KLA .98 .93 1.02 1.04 1.00 1.03 1.01
ATP 1.01 1.01 1.00 1.06 1.01 .99 1.08
KLA/ATP 1.07 1.01 .72 1.04 1.04 1.04 1.00
Cldn22
KLA  ATP  ATP+KLA
 NM_029383 claudin 22 (Cldn22), mRNA [NM_029383] KLA .99 .99 .99 .99 .99 .98 .96
ATP 1.01 .95 .99 .98 1.06 .92 .98
KLA/ATP 1.02 1.07 .96 1.00 1.02 1.04 .99
Cldn23
KLA  ATP  ATP+KLA
 NM_027998 claudin 23 (Cldn23), mRNA [NM_027998] KLA 1.33 1.38 1.29 1.23 1.13 1.13 1.20
ATP .99 1.04 1.11 1.41 1.44 1.23 1.14
KLA/ATP 1.42 1.34 1.29 1.33 1.30 1.23 1.73
Cldn3
KLA  ATP  ATP+KLA
 NM_009902 claudin 3 (Cldn3), mRNA [NM_009902] KLA 1.04 1.02 1.06 1.09 1.08 1.13 1.09
ATP 1.02 1.02 1.06 1.03 1.01 1.00 1.01
KLA/ATP 1.07 1.05 1.19 1.10 1.07 1.13 1.15
Cldn4
KLA  ATP  ATP+KLA
 NM_009903 claudin 4 (Cldn4), mRNA [NM_009903] KLA 1.05 .99 .94 1.02 1.05 1.05 .98
ATP 1.01 1.04 1.01 .95 .96 1.09 1.09
KLA/ATP .98 1.11 1.08 1.05 .86 .95 1.07
Cldn5
KLA  ATP  ATP+KLA
 NM_013805 claudin 5 (Cldn5), mRNA [NM_013805] KLA 1.08 1.08 1.23 1.13 1.16 1.18 1.18
ATP 1.01 1.02 1.03 1.03 1.05 1.00 1.06
KLA/ATP 1.14 1.18 1.13 1.09 1.05 1.15 1.16
Cldn6
KLA  ATP  ATP+KLA
 NM_018777 claudin 6 (Cldn6), mRNA [NM_018777] KLA 1.06 1.04 .98 1.01 1.03 .99 .91
ATP .98 1.01 .94 .99 .95 1.14 1.07
KLA/ATP 1.02 .96 1.08 1.04 1.01 .95 1.05
Cldn7
KLA  ATP  ATP+KLA
 NM_016887 claudin 7 (Cldn7), mRNA [NM_016887] KLA 1.21 1.23 1.33 1.38 1.44 1.26 1.01
ATP 1.01 1.01 1.07 1.01 1.04 1.04 1.03
KLA/ATP 1.22 1.28 1.24 2.23 1.42 1.17 1.07
Cldn8
KLA  ATP  ATP+KLA
 NM_018778 claudin 8 (Cldn8), mRNA [NM_018778] KLA .98 .86 1.00 .98 1.02 1.06 .97
ATP .93 .99 1.01 1.00 1.05 1.01 1.03
KLA/ATP .98 1.08 .96 1.00 1.02 .98 1.00
Cldn9
KLA  ATP  ATP+KLA
 NM_020293 claudin 9 (Cldn9), mRNA [NM_020293] KLA 1.29 1.24 1.37 1.34 1.32 1.37 1.55
ATP .92 .90 1.30 1.47 1.43 1.32 1.12
KLA/ATP 1.16 1.26 2.03 1.63 1.89 1.39 1.30
D430028G
21Rik
KLA  ATP  ATP+KLA
 NM_144888 RIKEN cDNA D430028G21 gene (D430028G21Rik), mRNA [NM_144888] KLA .56 .54 .61 .60 .74 1.03 1.06
ATP 1.07 .99 .69 .66 .48 .96 1.38
KLA/ATP .61 .60 .38 .41 .42 1.00 1.40
Ddx58
KLA  ATP  ATP+KLA
 NM_172689 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58), mRNA [NM_172689] KLA 8.80 9.12 9.70 9.96 9.92 7.85 5.67
ATP 1.06 .89 .97 .89 .80 3.03 3.67
KLA/ATP 9.18 9.23 10.31 9.25 7.29 6.93 8.99
Egf
KLA  ATP  ATP+KLA
 NM_010113 epidermal growth factor (Egf), mRNA [NM_010113] KLA .89 .90 .81 .83 .83 .86 .92
ATP 1.03 1.03 .95 .84 .67 .79 .88
KLA/ATP .86 .86 .77 .77 .69 .78 .83
Egfr
KLA  ATP  ATP+KLA
 NM_007912 epidermal growth factor receptor (Egfr), transcript variant 2, mRNA [NM_007912] KLA 1.10 1.07 1.14 1.11 1.08 1.03 .90
ATP .99 1.00 1.04 .98 .97 1.15 1.14
KLA/ATP 1.07 1.10 1.16 1.08 1.01 .97 .94
Egfr
KLA  ATP  ATP+KLA
 NM_207655 epidermal growth factor receptor (Egfr), transcript variant 1, mRNA [NM_207655] KLA 1.57 1.44 1.47 1.31 .96 .92 .76
ATP .97 .93 1.10 1.00 1.41 2.97 .86
KLA/ATP 1.44 1.50 1.61 1.30 1.14 1.21 .82
Eif2ak1
KLA  ATP  ATP+KLA
 AK032508 adult male olfactory brain cDNA, RIKEN full-length enriched library, clone:6430574E03 product:EUKARYOTIC TRANSLATION INITIATION FACTOR 2 ALPHA KINASE 1 (EC 2.7.1.-) (HEME-REGULATED EUKARYOTIC INITIATION FACTOR EIF-2-ALPHA KINASE) (HEME-R KLA .65 .66 .65 .67 .67 .85 1.06
ATP 1.07 1.13 1.10 1.03 .70 .63 .72
KLA/ATP .68 .73 .70 .67 .65 .66 .47
Eif2ak1
KLA  ATP  ATP+KLA
 NM_013557 eukaryotic translation initiation factor 2 alpha kinase 1 (Eif2ak1), mRNA [NM_013557] KLA 1.16 1.19 1.32 1.21 1.58 1.51 1.59
ATP 1.19 1.27 .93 1.28 1.02 1.53 1.60
KLA/ATP 1.36 1.50 1.16 1.38 1.12 1.79 2.42
Eif2ak2
KLA  ATP  ATP+KLA
 NM_011163 eukaryotic translation initiation factor 2-alpha kinase 2 (Eif2ak2), mRNA [NM_011163] KLA 6.20 6.38 6.31 6.36 4.86 4.86 2.93
ATP 1.03 .78 .68 .37 .49 3.38 1.97
KLA/ATP 6.50 5.52 5.25 2.87 3.90 4.33 3.35
Eif2ak3
KLA  ATP  ATP+KLA
 AK041698 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630030N06 product:unclassifiable, full insert sequence. [AK041698] KLA .79 .77 .83 .80 .93 .87 .85
ATP .82 .82 .82 .92 .88 .85 .91
KLA/ATP .77 .76 .78 .80 .84 .86 .81
Eif2ak3
KLA  ATP  ATP+KLA
 NM_010121 eukaryotic translation initiation factor 2 alpha kinase 3 (Eif2ak3), mRNA [NM_010121] KLA .28 .28 .27 .29 .38 .36 .47
ATP 1.17 1.04 .62 .48 .54 .48 .67
KLA/ATP .29 .30 .26 .26 .34 .37 .32
Eif2ak4
KLA  ATP  ATP+KLA
 AF193344 GCN2gamma mRNA, complete cds [AF193344] KLA .78 .78 .66 .72 .79 .83 1.05
ATP .97 1.06 .97 .97 .98 .86 .94
KLA/ATP .81 .73 .62 .84 .81 .88 .90
Eif2ak4
KLA  ATP  ATP+KLA
 NM_013719 eukaryotic translation initiation factor 2 alpha kinase 4 (Eif2ak4), mRNA [NM_013719] KLA .60 .55 .49 .54 .59 .67 .91
ATP 1.11 1.18 1.00 .94 1.33 .90 .98
KLA/ATP .59 .54 .56 .58 .90 .86 .86
Eif2s1
KLA  ATP  ATP+KLA
 NM_026114 eukaryotic translation initiation factor 2, subunit 1 alpha (Eif2s1), mRNA [NM_026114] KLA 1.50 1.49 1.52 1.49 1.24 1.12 1.25
ATP 1.00 .98 1.16 1.05 1.03 1.10 .99
KLA/ATP 1.50 1.54 1.73 1.39 1.24 .87 .66
Eif3e
KLA  ATP  ATP+KLA
 NM_008388 eukaryotic translation initiation factor 3, subunit E (Eif3e), mRNA [NM_008388] KLA 1.24 1.29 1.21 1.17 .99 .75 .84
ATP .96 1.02 1.23 1.34 1.05 .77 .49
KLA/ATP 1.13 1.24 1.32 1.46 1.05 .65 .39
Grb2
KLA  ATP  ATP+KLA
 NM_008163 growth factor receptor bound protein 2 (Grb2), mRNA [NM_008163] KLA .92 .88 .90 1.27 1.43 1.22 1.00
ATP 1.02 .83 .51 .42 .92 .70 .57
KLA/ATP .84 .77 .61 .56 1.56 1.49 .52
Grb2
KLA  ATP  ATP+KLA
 U07617 Grb2 adaptor protein (grb2) mRNA, complete cds. [U07617] KLA .83 .80 .95 1.13 1.38 1.36 1.06
ATP .84 .74 .51 .41 .82 .74 .59
KLA/ATP .77 .70 .57 .54 1.49 1.39 .53
Gsk3b
KLA  ATP  ATP+KLA
 NM_019827 glycogen synthase kinase 3 beta (Gsk3b), mRNA [NM_019827] KLA 1.06 1.03 1.11 1.01 1.26 1.28 1.26
ATP 1.18 1.27 1.15 2.07 2.37 2.32 1.67
KLA/ATP 1.15 1.21 .98 1.50 1.67 2.50 2.99
Hras1
KLA  ATP  ATP+KLA
 NM_008284 Harvey rat sarcoma virus oncogene 1 (Hras1), mRNA [NM_008284] KLA .79 .82 .77 .82 .94 1.03 1.07
ATP 1.01 .95 .69 .83 .79 1.12 1.15
KLA/ATP .84 .77 .61 .65 .82 1.00 1.05
Ifit1
KLA  ATP  ATP+KLA
 NM_008331 interferon-induced protein with tetratricopeptide repeats 1 (Ifit1), mRNA [NM_008331] KLA 135.72 113.87 103.77 80.36 56.00 83.83 37.35
ATP 1.04 .85 .94 .76 2.31 49.86 32.09
KLA/ATP 125.55 117.42 90.59 105.68 85.74 135.36 156.56
Ifna12
KLA  ATP  ATP+KLA
 NM_177361 interferon alpha 12 (Ifna12), mRNA [NM_177361] KLA 1.25 1.26 1.34 1.16 1.06 1.10 1.09
ATP 1.01 .97 1.07 1.09 1.17 1.20 1.07
KLA/ATP 1.12 1.29 1.72 1.54 1.59 1.56 1.05
Ifna13
KLA  ATP  ATP+KLA
 NM_177347 interferon alpha 13 (Ifna13), mRNA [NM_177347] KLA 1.32 1.27 1.26 1.34 1.15 1.24 1.20
ATP .95 1.08 1.29 1.79 1.41 1.22 1.08
KLA/ATP 1.36 1.35 2.04 2.81 2.07 1.44 1.19
Ifna2
KLA  ATP  ATP+KLA
 K01411 gb|Mouse alpha-interferon (MuIFN-alpha), 3 cds & untranslated mRNA [K01411] KLA 1.02 1.03 1.10 .96 .93 .99 1.01
ATP 1.02 .98 1.00 .98 1.02 .97 .95
KLA/ATP 1.02 1.04 1.18 1.08 1.13 1.04 1.01
Ifna2
KLA  ATP  ATP+KLA
 NM_010503 interferon alpha 2 (Ifna2), mRNA [NM_010503] KLA 1.08 1.06 1.07 1.06 .98 1.02 1.05
ATP .94 1.06 1.11 1.30 1.24 1.25 1.21
KLA/ATP 1.03 1.20 1.19 1.35 1.52 1.60 1.18
Ifna4
KLA  ATP  ATP+KLA
 NM_010504 interferon alpha 4 (Ifna4), mRNA [NM_010504] KLA .99 1.04 1.05 .97 1.00 .96 .99
ATP 1.01 .96 .98 1.01 1.00 1.00 .97
KLA/ATP 1.10 1.09 1.05 1.04 1.01 .97 1.01
Ifna5
KLA  ATP  ATP+KLA
 NM_010505 interferon alpha 5 (Ifna5), mRNA [NM_010505] KLA 1.15 1.23 1.51 1.26 1.03 1.06 1.05
ATP .99 .94 1.11 1.00 1.09 1.07 1.03
KLA/ATP 1.12 1.29 1.46 1.47 1.24 1.32 1.03
Ifna9
KLA  ATP  ATP+KLA
 NM_010507 interferon alpha 9 (Ifna9), mRNA [NM_010507] KLA 1.05 1.09 1.20 1.06 1.08 1.06 1.02
ATP .99 1.08 1.18 1.21 1.09 .99 .97
KLA/ATP 1.09 1.23 1.19 1.24 1.18 1.16 1.04
Ifnab
KLA  ATP  ATP+KLA
 BC116864 interferon alpha B, mRNA (cDNA clone MGC:151241 IMAGE:40126183), complete cds [BC116864] KLA 1.20 1.33 1.29 1.30 1.20 1.20 1.08
ATP .99 .99 1.00 1.25 1.13 1.19 1.04
KLA/ATP 1.30 1.39 1.44 1.48 1.49 1.54 1.22
Ifnar1
KLA  ATP  ATP+KLA
 NM_010508 interferon (alpha and beta) receptor 1 (Ifnar1), mRNA [NM_010508] KLA 1.35 1.29 1.19 1.39 1.60 1.47 1.49
ATP 1.18 1.25 .94 1.06 1.07 1.48 1.52
KLA/ATP 1.56 1.57 .98 1.43 1.08 1.79 3.54
Ifnar2
KLA  ATP  ATP+KLA
 NM_010509 interferon (alpha and beta) receptor 2 (Ifnar2), transcript variant 1, mRNA [NM_010509] KLA 1.45 1.43 1.67 1.87 2.31 1.84 1.36
ATP .99 .92 .87 1.03 1.38 1.79 1.43
KLA/ATP 1.48 1.48 1.24 1.54 1.77 2.10 2.81
Ifnb1
KLA  ATP  ATP+KLA
 NM_010510 interferon beta 1, fibroblast (Ifnb1), mRNA [NM_010510] KLA 49.82 46.57 34.05 16.05 5.94 7.31 8.49
ATP .99 1.02 1.89 4.78 6.31 4.44 1.79
KLA/ATP 49.22 61.83 134.08 144.05 110.96 31.78 11.24
Ikbkb
KLA  ATP  ATP+KLA
 NM_010546 inhibitor of kappaB kinase beta (Ikbkb), mRNA [NM_010546] KLA 1.88 2.10 2.14 1.83 1.73 1.31 1.19
ATP .81 .74 .55 .49 .59 1.05 .96
KLA/ATP 1.86 1.73 1.39 1.12 .89 1.17 1.24
Ikbke
KLA  ATP  ATP+KLA
 NM_019777 inhibitor of kappaB kinase epsilon (Ikbke), mRNA [NM_019777] KLA 6.03 5.91 6.38 6.89 7.05 6.70 4.74
ATP 1.02 1.11 .82 1.16 1.18 2.08 1.90
KLA/ATP 6.04 6.71 5.69 5.30 2.49 2.33 5.43
Ikbkg
KLA  ATP  ATP+KLA
 AK042138 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630062P04 product:unclassifiable, full insert sequence. [AK042138] KLA .92 .87 .78 .78 .87 .88 .62
ATP .84 .71 .80 .50 1.15 2.33 .61
KLA/ATP .72 .69 .74 .48 1.06 1.97 .68
Ikbkg
KLA  ATP  ATP+KLA
 NM_010547 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 1, mRNA [NM_010547] KLA 1.51 1.63 1.74 1.83 1.83 1.73 1.72
ATP .80 .79 .82 .75 .66 2.58 2.37
KLA/ATP 1.43 1.42 1.17 1.04 .71 1.54 3.17
Ikbkg
KLA  ATP  ATP+KLA
 NM_178590 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 2, mRNA [NM_178590] KLA .84 .93 .86 .91 1.03 .89 .88
ATP 1.03 .98 .68 .56 .51 .93 .68
KLA/ATP .89 .81 .55 .52 .41 .67 .65
Irf1
KLA  ATP  ATP+KLA
 NM_008390 interferon regulatory factor 1 (Irf1), mRNA [NM_008390] KLA 10.08 9.47 8.27 7.31 6.74 6.39 3.17
ATP .95 .81 .80 3.61 2.99 4.15 1.77
KLA/ATP 10.40 10.08 6.59 8.23 12.18 7.53 7.82
Irf3
KLA  ATP  ATP+KLA
 ENSMUST00000107835 ens|Interferon regulatory factor 3 (IRF-3). [Source:Uniprot/SWISSPROT;Acc:P70671] [ENSMUST00000107835] KLA .55 .56 .60 .72 .88 .88 .98
ATP .77 .58 .50 .46 .80 .97 1.03
KLA/ATP .51 .46 .49 .53 .92 .85 .79
Irf3
KLA  ATP  ATP+KLA
 NM_016849 interferon regulatory factor 3 (Irf3), mRNA [NM_016849] KLA .79 .75 .71 .83 .88 1.07 .99
ATP .92 .84 .88 .61 .54 1.27 1.22
KLA/ATP .78 .78 .75 .58 .70 1.13 1.38
Irf7
KLA  ATP  ATP+KLA
 NM_016850 interferon regulatory factor 7 (Irf7), mRNA [NM_016850] KLA 4.90 4.72 5.85 5.82 7.67 10.64 15.44
ATP 1.14 1.10 .86 1.18 .96 2.46 12.17
KLA/ATP 5.41 5.22 4.15 6.29 5.31 9.74 29.08
Irf9
KLA  ATP  ATP+KLA
 NM_008394 interferon regulatory factor 9 (Irf9), mRNA [NM_008394] KLA 1.96 1.99 2.13 1.83 1.81 1.85 1.71
ATP 1.08 1.06 .96 1.19 1.21 2.33 2.42
KLA/ATP 2.31 2.30 1.92 2.85 2.29 3.20 4.37
Jak1
KLA  ATP  ATP+KLA
 AK029232 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4831433J01 product:Janus kinase 1, full insert sequence. [AK029232] KLA 1.25 1.13 1.19 1.31 1.24 1.17 1.14
ATP 1.01 1.11 .96 1.38 1.06 1.26 1.05
KLA/ATP 1.19 1.29 1.27 1.59 1.18 1.38 1.24
Jak1
KLA  ATP  ATP+KLA
 NM_146145 Janus kinase 1 (Jak1), mRNA [NM_146145] KLA 1.71 1.75 1.79 1.81 1.72 1.37 1.21
ATP 1.03 1.01 .75 1.04 1.32 1.90 1.14
KLA/ATP 1.84 1.73 1.49 2.07 2.01 1.83 1.68
Kras
KLA  ATP  ATP+KLA
 NM_021284 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Kras), mRNA [NM_021284] KLA .53 .49 .40 .42 .49 .95 1.05
ATP .98 1.01 1.16 1.17 1.39 1.29 1.74
KLA/ATP .50 .47 .50 .56 1.00 1.24 1.58
Ldlr
KLA  ATP  ATP+KLA
 NM_010700 low density lipoprotein receptor (Ldlr), mRNA [NM_010700] KLA 2.17 2.00 2.07 1.87 1.38 .78 1.00
ATP .98 .87 1.53 1.14 1.01 1.52 1.60
KLA/ATP 1.86 1.76 2.52 1.55 1.59 .84 .82
Ldlr
KLA  ATP  ATP+KLA
 Z19521 gb|M.musculus Ldlr mRNA encoding low density lipoprotein receptor. [Z19521] KLA 1.94 1.93 2.24 2.01 1.73 1.08 1.26
ATP 1.12 1.21 1.47 1.65 1.28 1.45 1.67
KLA/ATP 2.22 2.28 2.17 2.27 1.50 1.13 1.29
Mapk1
KLA  ATP  ATP+KLA
 NM_001038663 mitogen-activated protein kinase 1 (Mapk1), transcript variant 2, mRNA [NM_001038663] KLA .97 1.03 .93 .86 .79 1.01 1.04
ATP .96 1.18 1.01 1.13 .84 1.04 1.16
KLA/ATP .99 .99 .84 .87 .63 .96 1.26
Mapk1
KLA  ATP  ATP+KLA
 NM_011949 mitogen-activated protein kinase 1 (Mapk1), transcript variant 1, mRNA [NM_011949] KLA .88 .80 .80 .73 .75 .76 .65
ATP .97 .96 1.06 .88 .90 .68 .48
KLA/ATP .82 .81 .78 .65 .64 .64 .45
Mapk10
KLA  ATP  ATP+KLA
 AK076990 adult male testis cDNA, RIKEN full-length enriched library, clone:4930597C01 product:mitogen activated protein kinase 10, full insert sequence. [AK076990] KLA 1.03 1.05 .98 1.04 .94 .95 1.02
ATP 1.00 .99 1.06 .97 1.01 .96 .99
KLA/ATP 1.07 1.01 .95 1.05 .82 .95 .87
Mapk10
KLA  ATP  ATP+KLA
 NM_009158 mitogen-activated protein kinase 10 (Mapk10), transcript variant 1, mRNA [NM_009158] KLA .95 1.00 .97 1.01 .99 1.01 .95
ATP 1.01 1.02 .98 1.01 1.04 1.01 .99
KLA/ATP 1.05 .99 1.01 .98 .92 .97 .98
Mapk11
KLA  ATP  ATP+KLA
 NM_011161 mitogen-activated protein kinase 11 (Mapk11), mRNA [NM_011161] KLA 1.28 1.30 1.41 1.46 1.58 1.29 .98
ATP .96 .95 .89 .82 .79 1.09 .85
KLA/ATP 1.44 1.42 1.32 1.23 1.23 .74 .66
Mapk12
KLA  ATP  ATP+KLA
 NM_013871 mitogen-activated protein kinase 12 (Mapk12), mRNA [NM_013871] KLA .94 .86 .87 .81 .77 .68 .49
ATP .97 .83 .92 .90 .86 .90 .51
KLA/ATP .91 .89 .88 .85 1.12 1.14 .53
Mapk13
KLA  ATP  ATP+KLA
 NM_011950 mitogen-activated protein kinase 13 (Mapk13), mRNA [NM_011950] KLA 1.22 1.21 1.35 1.26 1.24 1.13 1.01
ATP 1.08 1.00 1.20 1.20 1.13 1.22 1.39
KLA/ATP 1.22 1.27 1.30 1.30 1.21 1.11 1.47
Mapk14
KLA  ATP  ATP+KLA
 NM_011951 mitogen-activated protein kinase 14 (Mapk14), mRNA [NM_011951] KLA .70 .70 .62 .54 .67 .88 1.11
ATP 1.03 .98 .87 .69 .48 .78 .66
KLA/ATP .74 .68 .52 .46 .38 .45 .62
Mapk3
KLA  ATP  ATP+KLA
 NM_011952 mitogen-activated protein kinase 3 (Mapk3), mRNA [NM_011952] KLA .81 .85 .88 .72 .79 .73 .90
ATP 1.13 1.30 .92 1.48 1.08 .68 1.03
KLA/ATP 1.01 1.01 .66 1.13 .77 .77 1.16
Mapk8
KLA  ATP  ATP+KLA
 AK162915 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330031O19 product:mitogen activated protein kinase 8, full insert sequence [AK162915] KLA .94 .86 .80 .83 .77 .85 .83
ATP 1.08 1.12 .94 .80 .83 .71 .75
KLA/ATP .83 .81 .80 .74 .74 .75 .67
Mapk8
KLA  ATP  ATP+KLA
 AK163829 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130070A06 product:mitogen activated protein kinase 8, full insert sequence [AK163829] KLA .65 .61 .66 .70 .90 1.02 1.03
ATP .99 .94 1.68 1.44 1.75 1.84 1.10
KLA/ATP .63 .67 1.11 1.00 2.01 1.68 1.15
Mapk8
KLA  ATP  ATP+KLA
 NM_016700 mitogen-activated protein kinase 8 (Mapk8), mRNA [NM_016700] KLA .96 1.00 .94 .96 .94 .99 1.04
ATP 1.01 1.05 1.01 .99 1.03 .98 1.02
KLA/ATP .96 .97 .96 .97 .93 .94 .96
Mapk9
KLA  ATP  ATP+KLA
 NM_016961 mitogen-activated protein kinase 9 (Mapk9), transcript variant 2, mRNA [NM_016961] KLA 1.28 1.37 1.59 1.60 1.61 1.43 1.38
ATP 1.03 .99 .74 .71 .79 1.20 1.01
KLA/ATP 1.53 1.30 1.07 .99 .83 1.10 1.40
Mapk9
KLA  ATP  ATP+KLA
 NM_207692 mitogen-activated protein kinase 9 (Mapk9), transcript variant 1, mRNA [NM_207692] KLA 1.39 1.53 1.69 1.69 1.55 1.44 1.51
ATP .95 .92 .75 .85 .70 1.46 1.17
KLA/ATP 1.37 1.35 .99 1.18 .91 1.22 1.62
Mm.10799
6
KLA  ATP  ATP+KLA
 94407580 Unknown KLA .97 .95 .93 1.00 .95 1.00 1.00
ATP .95 1.03 .96 .92 1.03 .93 1.05
KLA/ATP .99 .91 .97 .92 .90 .90 .92
Mm.14301
KLA  ATP  ATP+KLA
 21630282 Unknown KLA 3.97 3.92 3.89 4.78 4.16 4.22 3.83
ATP .97 .93 1.27 1.16 1.01 2.62 4.12
KLA/ATP 3.93 4.01 4.75 4.44 4.41 3.51 5.56
Mm.15909
3
KLA  ATP  ATP+KLA
 149272242 Unknown KLA 1.01 .97 1.01 1.01 1.05 1.02 .99
ATP 1.04 1.01 .95 1.02 .99 .94 .96
KLA/ATP .96 1.01 1.04 .94 .94 1.05 .98
Mm.21312
8
KLA  ATP  ATP+KLA
 141801344 Unknown KLA .96 .95 .83 .77 .52 .99 1.32
ATP .80 .82 1.09 .80 .83 1.19 1.46
KLA/ATP .78 .92 .98 .62 .71 .94 1.41
Mm.22094
6
KLA  ATP  ATP+KLA
 27545180 Unknown KLA 1.00 .93 .97 1.05 1.06 1.29 1.13
ATP .90 .94 1.25 1.18 .85 .62 1.20
KLA/ATP .86 .99 1.14 .99 .83 .70 1.26
Mm.25381
9
KLA  ATP  ATP+KLA
 118130676 Unknown KLA 1.81 1.88 1.96 1.62 1.89 2.44 1.56
ATP .92 .91 1.24 1.01 1.16 2.06 1.95
KLA/ATP 1.62 1.86 1.86 1.41 1.89 2.37 1.97
Mm.27970
KLA  ATP  ATP+KLA
 13994135 Unknown KLA 1.06 1.11 1.16 1.07 1.11 1.08 .95
ATP 1.02 1.09 1.05 1.05 .94 1.16 1.32
KLA/ATP 1.10 1.19 1.11 1.04 1.08 1.02 1.33
Mm.37195
6
KLA  ATP  ATP+KLA
 94405889 Unknown KLA 57.25 49.51 48.65 57.96 50.90 57.18 41.44
ATP 1.02 .90 1.21 1.10 2.19 27.45 33.37
KLA/ATP 48.99 49.58 73.18 63.02 73.34 72.06 76.66
Mm.37708
7
KLA  ATP  ATP+KLA
 158631169 Unknown KLA .98 .98 1.06 1.06 .91 .97 1.04
ATP 1.00 1.07 1.01 1.06 1.09 .99 1.02
KLA/ATP 1.08 1.06 1.16 1.11 1.16 1.12 1.04
Mm.37899
0
KLA  ATP  ATP+KLA
 144227203 Unknown KLA 5.51 4.67 4.55 6.22 4.34 4.26 2.87
ATP 1.00 .76 .68 .41 .53 3.65 1.93
KLA/ATP 4.53 4.63 5.45 2.73 3.51 4.58 3.75
Mm.4387
KLA  ATP  ATP+KLA
 133892666 Unknown KLA .85 .87 .85 .89 .77 .91 1.18
ATP 1.01 1.01 .87 1.07 .75 .86 .93
KLA/ATP .88 .86 .77 .81 .72 .91 .84
Mm.46002
4
KLA  ATP  ATP+KLA
 38348245 Unknown KLA 1.22 1.25 1.25 1.19 1.22 1.47 1.14
ATP 1.03 .94 1.01 1.01 2.67 2.31 1.37
KLA/ATP 1.35 1.19 1.27 1.22 1.99 1.83 1.45
Mm.47351
0
KLA  ATP  ATP+KLA
 162287332 Unknown KLA 4.46 4.82 5.29 4.00 2.26 1.25 1.10
ATP 1.24 1.72 1.02 2.08 1.66 2.53 .55
KLA/ATP 6.11 7.67 4.29 6.99 3.11 2.86 2.30
Mm.57127
KLA  ATP  ATP+KLA
 117168292 Unknown KLA 1.20 1.25 1.28 1.18 1.14 1.13 1.12
ATP .98 .95 1.11 1.06 1.05 1.05 1.09
KLA/ATP 1.22 1.24 1.48 1.55 1.40 1.21 1.07
Nfkb1
KLA  ATP  ATP+KLA
 BC050841 nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, mRNA (cDNA clone IMAGE:6392793), complete cds. [BC050841] KLA 5.81 4.96 4.77 3.21 3.37 2.00 1.71
ATP 1.39 1.52 3.25 12.63 13.64 4.80 1.08
KLA/ATP 7.21 8.69 19.53 23.93 11.70 2.85 2.01
Nfkb1
KLA  ATP  ATP+KLA
 M57999 gb|Mouse transcription factor NF-kappa-B DNA binding subunit mRNA, complete cds. [M57999] KLA 8.55 7.87 7.35 6.13 3.51 1.85 1.38
ATP .98 .96 1.21 3.06 5.29 4.67 .69
KLA/ATP 7.32 7.20 8.71 10.82 5.55 2.77 1.54
Nfkbia
KLA  ATP  ATP+KLA
 NM_010907 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA [NM_010907] KLA 18.65 18.46 13.63 17.88 14.25 9.17 7.92
ATP .91 1.09 7.11 32.39 17.44 10.49 1.72
KLA/ATP 15.57 17.66 15.73 23.91 13.83 10.73 9.48
Nr1h3
KLA  ATP  ATP+KLA
 NM_013839 nuclear receptor subfamily 1, group H, member 3 (Nr1h3), mRNA [NM_013839] KLA 1.80 1.74 1.73 2.19 4.14 5.99 8.67
ATP 1.12 .93 .69 .83 1.14 1.09 2.92
KLA/ATP 1.86 1.77 1.13 1.15 1.44 1.38 6.71
Nras
KLA  ATP  ATP+KLA
 NM_010937 neuroblastoma ras oncogene (Nras), mRNA [NM_010937] KLA 1.20 1.22 1.27 1.20 1.09 .91 .84
ATP .98 .91 .69 .61 .59 .67 .78
KLA/ATP 1.22 1.14 .97 .79 .73 .61 .72
OTTMUSG0
0000016644
KLA  ATP  ATP+KLA
 NM_001110517 predicted gene, OTTMUSG00000016644 (OTTMUSG00000016644), transcript variant 1, mRNA [NM_001110517] KLA 111.73 107.32 111.47 133.12 110.94 145.92 83.83
ATP 1.00 .93 1.20 1.40 1.93 24.54 43.21
KLA/ATP 99.78 116.52 147.75 125.04 144.55 182.77 171.34
Oas1a
KLA  ATP  ATP+KLA
 NM_145211 2-5 oligoadenylate synthetase 1A (Oas1a), mRNA [NM_145211] KLA 2.26 2.33 2.50 2.33 3.11 3.74 3.99
ATP .99 1.04 .93 1.03 .91 1.63 3.44
KLA/ATP 2.49 2.39 1.91 2.51 2.28 3.09 6.06
Oas1b
KLA  ATP  ATP+KLA
 NM_001083925 2-5 oligoadenylate synthetase 1B (Oas1b), mRNA [NM_001083925] KLA 3.54 3.55 4.22 4.22 4.93 5.27 4.14
ATP 1.13 1.08 1.05 1.19 1.06 2.13 2.67
KLA/ATP 3.53 3.76 3.24 5.16 4.36 4.05 7.31
Oas1g
KLA  ATP  ATP+KLA
 NM_011852 2-5 oligoadenylate synthetase 1G (Oas1g), mRNA [NM_011852] KLA 2.58 2.75 2.53 2.84 2.60 2.74 2.56
ATP .97 1.03 1.20 1.17 1.07 1.82 2.47
KLA/ATP 2.58 2.80 2.68 2.60 2.21 2.27 3.01
Oas2
KLA  ATP  ATP+KLA
 NM_145227 2-5 oligoadenylate synthetase 2 (Oas2), mRNA [NM_145227] KLA 3.37 3.26 3.43 2.80 3.59 3.57 2.15
ATP 1.10 1.20 1.04 .86 .94 3.23 3.09
KLA/ATP 3.85 3.75 3.15 3.70 4.00 5.52 7.31
Oas3
KLA  ATP  ATP+KLA
 NM_145226 2-5 oligoadenylate synthetase 3 (Oas3), mRNA [NM_145226] KLA 2.32 2.35 2.67 2.63 3.37 3.80 4.07
ATP 1.06 1.10 1.02 1.26 1.02 1.47 3.58
KLA/ATP 2.62 2.57 2.39 3.18 2.67 3.05 6.15
Ocln
KLA  ATP  ATP+KLA
 NM_008756 occludin (Ocln), mRNA [NM_008756] KLA 1.02 1.04 1.03 1.03 .99 1.05 1.00
ATP 1.03 .98 1.01 1.07 1.05 1.05 1.04
KLA/ATP 1.09 1.00 1.03 1.05 1.06 1.03 1.01
Pdk1
KLA  ATP  ATP+KLA
 AK165090 2 days pregnant adult female ovary cDNA, RIKEN full-length enriched library, clone:E330005M21 product:hypothetical protein, full insert sequence. [AK165090] KLA .86 .77 .71 .67 .45 .29 .35
ATP 1.06 .88 1.21 .72 .60 .26 .15
KLA/ATP .81 .74 .97 .57 .51 .22 .09
Pdk1
KLA  ATP  ATP+KLA
 NM_172665 pyruvate dehydrogenase kinase, isoenzyme 1 (Pdk1), nuclear gene encoding mitochondrial protein, mRNA [NM_172665] KLA .92 .94 .91 .79 .63 .46 .51
ATP .95 1.03 1.06 1.02 .63 .31 .37
KLA/ATP .88 .91 .91 .89 .62 .31 .27
Pias1
KLA  ATP  ATP+KLA
 NM_019663 protein inhibitor of activated STAT 1 (Pias1), mRNA [NM_019663] KLA 1.60 1.58 1.85 1.69 1.49 1.22 1.00
ATP 1.09 1.10 .93 .86 .96 .68 .88
KLA/ATP 1.64 1.41 1.29 1.32 1.37 1.01 1.26
Pik3ca
KLA  ATP  ATP+KLA
 ENSMUST00000108243 ens|Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K). [Source:Uniprot/SWISSPROT;Acc:P42337] [ENSMUST00000108243] KLA 1.07 1.01 .91 .90 .98 .96 .86
ATP 1.03 .87 1.12 .63 1.22 1.86 .60
KLA/ATP 1.05 .82 .91 .61 1.17 1.26 .63
Pik3ca
KLA  ATP  ATP+KLA
 NM_008839 phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca), mRNA [NM_008839] KLA 1.15 1.11 1.05 .82 .99 1.03 1.27
ATP .98 1.00 .79 .75 .96 1.32 1.10
KLA/ATP 1.10 .98 .64 .72 .80 1.20 1.41
Pik3cb
KLA  ATP  ATP+KLA
 NM_029094 phosphatidylinositol 3-kinase, catalytic, beta polypeptide (Pik3cb), mRNA [NM_029094] KLA 1.06 1.06 1.03 .73 .68 .98 1.69
ATP 1.04 1.21 .95 1.02 .85 .93 1.73
KLA/ATP 1.15 1.27 .73 .83 .58 .81 1.81
Pik3cd
KLA  ATP  ATP+KLA
 NM_008840 phosphatidylinositol 3-kinase catalytic delta polypeptide (Pik3cd), transcript variant 1, mRNA [NM_008840] KLA 2.28 2.42 3.10 4.17 3.35 2.31 1.34
ATP 1.02 .91 .99 .63 .30 .67 .80
KLA/ATP 2.14 2.23 2.70 1.51 1.17 .85 .72
Pik3cd
KLA  ATP  ATP+KLA
 U86587 phosphatidylinositol 3-kinase catalytic subunit p110 delta mRNA, complete cds. [U86587] KLA 2.21 2.24 3.71 3.17 3.67 2.66 1.48
ATP 1.00 1.03 .93 .96 .46 .75 .97
KLA/ATP 2.27 2.32 1.97 2.02 1.01 .99 .98
Pik3cg
KLA  ATP  ATP+KLA
 NM_020272 phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg), mRNA [NM_020272] KLA .53 .53 .61 .64 .97 .86 .79
ATP 1.01 1.13 .88 .89 .52 .53 .53
KLA/ATP .58 .53 .43 .60 .40 .43 .62
Pik3r1
KLA  ATP  ATP+KLA
 NM_001077495 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 2, mRNA [NM_001077495] KLA 1.05 1.07 1.03 1.00 1.01 1.20 .85
ATP .97 1.02 1.48 1.42 1.76 1.33 1.23
KLA/ATP 1.11 1.12 1.06 1.17 1.24 .99 1.12
Pik3r2
KLA  ATP  ATP+KLA
 NM_008841 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2), mRNA [NM_008841] KLA .50 .50 .48 .43 .46 .66 .75
ATP .78 .68 .45 .43 .28 .57 1.37
KLA/ATP .49 .38 .32 .33 .38 .67 1.10
Pik3r3
KLA  ATP  ATP+KLA
 NM_181585 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) (Pik3r3), mRNA [NM_181585] KLA 1.59 1.49 1.37 1.17 1.05 1.55 1.41
ATP 1.12 1.00 1.33 1.70 2.01 2.37 2.02
KLA/ATP 1.63 1.54 1.58 1.70 2.43 2.68 1.92
Pik3r5
KLA  ATP  ATP+KLA
 NM_177320 phosphoinositide-3-kinase, regulatory subunit 5, p101 (Pik3r5), mRNA [NM_177320] KLA 3.57 3.58 4.16 3.54 4.11 2.59 2.39
ATP 1.08 1.08 .93 1.67 3.11 1.88 1.34
KLA/ATP 3.91 3.70 3.30 3.80 2.70 2.04 3.00
Ppara
KLA  ATP  ATP+KLA
 NM_011144 peroxisome proliferator activated receptor alpha (Ppara), transcript variant 1, mRNA [NM_011144] KLA 1.01 3.31 .99 1.02 1.00 1.00 .98
ATP 1.00 1.02 .99 1.00 1.00 1.00 1.01
KLA/ATP 1.01 1.01 1.02 .99 1.00 1.02 .99
Ppp2ca
KLA  ATP  ATP+KLA
 NM_019411 protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Ppp2ca), mRNA [NM_019411] KLA 1.17 1.13 1.18 1.20 1.54 1.45 1.34
ATP 1.09 1.20 1.07 1.33 1.56 2.04 1.43
KLA/ATP 1.14 1.17 1.15 1.49 1.59 2.37 2.02
Ppp2cb
KLA  ATP  ATP+KLA
 NM_017374 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Ppp2cb), mRNA [NM_017374] KLA 1.32 1.33 1.37 1.24 1.27 1.09 1.18
ATP .94 .93 .82 .91 1.22 2.01 1.08
KLA/ATP 1.24 1.14 .80 .97 1.13 1.54 1.18
Ppp2r1a
KLA  ATP  ATP+KLA
 NM_016891 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (Ppp2r1a), mRNA [NM_016891] KLA 1.44 1.39 1.47 1.37 1.69 1.33 1.16
ATP 1.18 1.55 .85 1.67 1.38 .99 1.24
KLA/ATP 1.66 1.98 .97 2.33 1.41 1.65 1.38
Ppp2r1b
KLA  ATP  ATP+KLA
 NM_001034085 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform (Ppp2r1b), transcript variant 1, mRNA [NM_001034085] KLA 1.26 1.17 1.14 1.13 1.12 1.11 .99
ATP .90 .90 .96 .98 1.59 1.71 1.16
KLA/ATP 1.23 1.16 .99 1.00 1.54 1.34 1.24
Ppp2r1b
KLA  ATP  ATP+KLA
 NM_028614 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform (Ppp2r1b), transcript variant 2, mRNA [NM_028614] KLA 2.38 2.38 2.53 1.80 1.52 .95 1.16
ATP 1.17 1.29 1.04 1.09 1.16 1.19 1.00
KLA/ATP 2.59 2.78 1.82 2.31 1.34 1.03 .75
Ppp2r2a
KLA  ATP  ATP+KLA
 NM_028032 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform (Ppp2r2a), mRNA [NM_028032] KLA 2.18 2.42 2.58 2.17 2.08 1.83 1.57
ATP 1.06 1.12 .90 1.28 1.76 1.70 1.39
KLA/ATP 2.55 2.38 1.62 2.68 2.25 2.55 1.86
Ppp2r2b
KLA  ATP  ATP+KLA
 AK086561 15 days embryo head cDNA, RIKEN full-length enriched library, clone:D930037C08 product:unclassifiable, full insert sequence [AK086561] KLA .94 1.02 1.07 1.02 1.02 .97 .98
ATP 1.01 1.04 1.01 .99 .97 .95 1.00
KLA/ATP 1.04 1.06 1.01 .96 1.02 .90 .93
Ppp2r2b
KLA  ATP  ATP+KLA
 NM_028392 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform (Ppp2r2b), transcript variant 2, mRNA [NM_028392] KLA 1.01 1.02 .96 1.00 1.04 1.01 1.00
ATP 1.00 .96 1.07 .93 .95 1.01 1.03
KLA/ATP .95 1.01 1.06 1.07 .98 1.02 1.03
Ppp2r2c
KLA  ATP  ATP+KLA
 NM_172994 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform (Ppp2r2c), mRNA [NM_172994] KLA .97 .98 .96 1.02 1.02 1.06 1.01
ATP .96 1.05 1.03 .98 1.01 1.04 1.06
KLA/ATP .98 .98 1.00 .96 1.00 .86 1.10
Ppp2r2d
KLA  ATP  ATP+KLA
 NM_026391 protein phosphatase 2, regulatory subunit B, delta isoform (Ppp2r2d), mRNA [NM_026391] KLA 1.07 1.03 1.14 1.18 1.16 1.27 1.13
ATP .96 .93 .95 .76 1.34 2.21 1.22
KLA/ATP 1.01 1.01 1.01 .87 1.91 2.19 2.18
Psme3
KLA  ATP  ATP+KLA
 NM_011192 proteaseome (prosome, macropain) 28 subunit, 3 (Psme3), mRNA [NM_011192] KLA 1.10 1.16 1.13 1.05 1.05 1.04 1.18
ATP 1.02 1.14 1.07 1.36 1.16 1.35 1.12
KLA/ATP 1.14 1.31 1.14 1.33 1.09 1.13 1.16
Raf1
KLA  ATP  ATP+KLA
 AK036317 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630056E02 product:v-raf-1 leukemia viral oncogene 1, full insert sequence. [AK036317] KLA 1.47 1.34 1.55 1.29 1.59 1.32 1.46
ATP 1.05 .98 .54 .63 3.32 2.07 1.01
KLA/ATP 1.57 1.33 .79 .96 2.26 1.38 1.35
Raf1
KLA  ATP  ATP+KLA
 NM_029780 v-raf-leukemia viral oncogene 1 (Raf1), mRNA [NM_029780] KLA 1.65 1.64 1.93 1.77 1.77 1.72 1.81
ATP .95 .96 .83 .80 2.22 2.92 1.19
KLA/ATP 1.68 1.64 1.39 1.32 1.85 2.50 2.06
Rela
KLA  ATP  ATP+KLA
 NM_009045 v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela), mRNA [NM_009045] KLA 2.05 2.05 2.07 1.75 1.83 1.58 1.33
ATP 1.03 1.08 1.10 1.44 1.61 2.48 1.05
KLA/ATP 2.17 2.27 2.05 2.47 1.93 2.35 2.02
Ripk1
KLA  ATP  ATP+KLA
 NM_009068 receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1), mRNA [NM_009068] KLA 1.32 1.33 1.50 1.09 1.00 1.11 1.13
ATP .98 .94 .60 .59 1.35 1.56 1.45
KLA/ATP 1.48 1.30 1.01 1.05 1.36 1.53 1.37
Rnasel
KLA  ATP  ATP+KLA
 NM_011882 ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent) (Rnasel), mRNA [NM_011882] KLA .25 .24 .26 .35 .50 .47 .31
ATP .98 .91 .60 .40 .36 1.12 .53
KLA/ATP .24 .25 .23 .22 .32 1.16 .52
Rxra
KLA  ATP  ATP+KLA
 NM_011305 retinoid X receptor alpha (Rxra), mRNA [NM_011305] KLA .53 .55 .50 .52 .54 .85 1.09
ATP .95 1.00 1.18 1.00 .82 1.20 1.65
KLA/ATP .57 .55 .58 .55 .67 1.07 1.57
Scarb1
KLA  ATP  ATP+KLA
 NM_016741 scavenger receptor class B, member 1 (Scarb1), mRNA [NM_016741] KLA .62 .60 .60 .51 .45 .40 .48
ATP 1.04 1.14 .68 .89 .53 .46 .82
KLA/ATP .73 .67 .40 .55 .34 .30 .39
Socs3
KLA  ATP  ATP+KLA
 NM_007707 suppressor of cytokine signaling 3 (Socs3), mRNA [NM_007707] KLA 7.56 6.68 6.29 7.36 6.47 7.03 5.33
ATP 1.51 1.75 4.63 6.27 6.92 7.74 4.64
KLA/ATP 6.82 6.77 9.19 8.32 9.51 8.98 8.33
Sos1
KLA  ATP  ATP+KLA
 NM_009231 Son of sevenless homolog 1 (Drosophila) (Sos1), mRNA [NM_009231] KLA 2.36 2.40 3.42 3.15 2.78 1.81 1.71
ATP .99 1.00 .99 1.15 1.14 1.25 1.24
KLA/ATP 2.41 2.26 1.95 2.44 1.47 1.66 1.37
Sos2
KLA  ATP  ATP+KLA
 XM_127051 gb|PREDICTED: Mus musculus Son of sevenless homolog 2 (Drosophila) (Sos2), mRNA [XM_127051] KLA .81 .77 .79 .92 1.04 1.06 1.20
ATP 1.00 1.00 1.09 .79 .68 .81 .94
KLA/ATP .77 .69 .71 .60 .64 .77 1.07
Stat1
KLA  ATP  ATP+KLA
 NM_009283 signal transducer and activator of transcription 1 (Stat1), mRNA [NM_009283] KLA 2.90 2.72 3.00 3.64 4.58 6.51 5.58
ATP 1.01 .92 .89 .72 .51 2.22 3.07
KLA/ATP 2.73 2.65 2.34 1.95 1.99 4.70 8.66
Stat2
KLA  ATP  ATP+KLA
 NM_019963 signal transducer and activator of transcription 2 (Stat2), mRNA [NM_019963] KLA 5.64 4.80 4.99 6.48 6.28 9.50 5.36
ATP .90 .80 1.03 .66 .97 4.90 4.07
KLA/ATP 4.47 4.88 6.34 4.27 6.76 9.49 11.43
Stat3
KLA  ATP  ATP+KLA
 NM_213659 signal transducer and activator of transcription 3 (Stat3), transcript variant 1, mRNA [NM_213659] KLA 4.36 4.42 4.67 6.02 4.95 3.45 1.46
ATP 1.01 .97 1.07 1.17 2.47 4.04 1.47
KLA/ATP 4.02 4.57 6.65 6.51 7.06 7.39 3.61
Tbk1
KLA  ATP  ATP+KLA
 NM_019786 TANK-binding kinase 1 (Tbk1), mRNA [NM_019786] KLA 2.55 2.76 3.22 2.67 2.56 2.29 1.96
ATP 1.13 1.30 1.12 1.07 1.29 1.41 1.40
KLA/ATP 2.84 3.17 2.58 2.43 1.70 2.15 2.37
Ticam1
KLA  ATP  ATP+KLA
 NM_174989 toll-like receptor adaptor molecule 1 (Ticam1), mRNA [NM_174989] KLA 1.45 1.63 2.02 2.36 3.12 2.34 2.21
ATP 1.16 1.19 .90 2.58 4.78 2.04 1.80
KLA/ATP 1.79 1.71 1.07 2.89 5.60 3.26 3.50
Tlr3
KLA  ATP  ATP+KLA
 NM_126166 toll-like receptor 3 (Tlr3), mRNA [NM_126166] KLA 8.54 10.04 12.64 11.83 10.51 7.08 3.09
ATP 1.09 1.16 1.16 1.16 .77 1.77 2.23
KLA/ATP 10.00 11.77 10.12 12.97 10.43 8.74 7.11
Tnf
KLA  ATP  ATP+KLA
 NM_013693 tumor necrosis factor (Tnf), mRNA [NM_013693] KLA 13.35 12.76 10.71 9.03 10.64 7.39 8.32
ATP 2.01 2.48 8.27 19.20 9.72 4.09 1.49
KLA/ATP 12.72 15.76 12.73 17.34 5.10 3.61 6.07
Tnfrsf1a
KLA  ATP  ATP+KLA
 NM_011609 tumor necrosis factor receptor superfamily, member 1a (Tnfrsf1a), mRNA [NM_011609] KLA 1.74 1.71 1.90 2.16 1.95 1.74 1.16
ATP .95 .83 .55 .41 .41 1.55 1.32
KLA/ATP 1.58 1.49 1.19 1.03 .98 2.02 2.10
Tradd
KLA  ATP  ATP+KLA
 NM_001033161 TNFRSF1A-associated via death domain (Tradd), mRNA [NM_001033161] KLA .77 .71 .82 .89 .89 1.11 1.06
ATP 1.00 .90 1.01 .73 .59 1.34 1.50
KLA/ATP .79 .73 .83 .63 .72 1.11 1.73
Traf2
KLA  ATP  ATP+KLA
 NM_009422 Tnf receptor-associated factor 2 (Traf2), mRNA [NM_009422] KLA 3.38 3.62 3.49 3.36 3.49 3.39 2.68
ATP .97 1.04 1.00 1.10 1.54 2.40 1.55
KLA/ATP 3.38 3.16 2.93 2.74 2.67 3.11 4.70
Traf3
KLA  ATP  ATP+KLA
 NM_011632 Tnf receptor-associated factor 3 (Traf3), transcript variant 1, mRNA [NM_011632] KLA .52 .49 .51 .49 .80 .98 1.22
ATP .93 .92 .95 1.13 2.70 1.80 1.42
KLA/ATP .56 .50 .49 1.07 2.94 1.92 1.65
Traf6
KLA  ATP  ATP+KLA
 NM_009424 Tnf receptor-associated factor 6 (Traf6), mRNA [NM_009424] KLA 1.19 1.28 1.34 1.20 1.23 1.23 1.28
ATP 1.06 1.12 .92 1.15 2.46 1.84 1.40
KLA/ATP 1.32 1.37 .89 1.16 1.45 1.49 1.46
Trp53
KLA  ATP  ATP+KLA
 NM_011640 transformation related protein 53 (Trp53), mRNA [NM_011640] KLA 1.25 1.37 1.11 .86 .72 .71 .95
ATP 1.15 1.32 .90 1.85 1.26 .68 .70
KLA/ATP 1.66 1.49 .80 1.76 .81 .65 .74
Tyk2
KLA  ATP  ATP+KLA
 NM_018793 tyrosine kinase 2 (Tyk2), mRNA [NM_018793] KLA 2.91 2.95 3.42 3.26 3.85 2.35 1.42
ATP 1.09 1.01 .68 .64 .59 .86 1.10
KLA/ATP 2.95 3.04 2.23 1.82 1.24 1.27 2.09