Microarray data for Ppap2a: fold-change ratios

Bone marrow-derived macrophage cells treated with Kdo2-Lipid A (KLA) and ATP

Gene Time course graph Description Treatment 15min 30min 1h 2h 4h 8h 20h
Ppap2a
KLA  ATP  ATP+KLA
phosphatidic acid phosphatase 2a (Ppap2a), transcript variant 2, mRNA [NM_008903] KLA 2.62 2.86 4.01 5.61 7.84 10.88 16.35
 ATP 1.01 1.02 1.09 1.28 1.27 2.38 1.44
 ATP+KLA 2.78 2.78 2.99 3.43 2.85 3.59 6.59

Bone marrow-derived macrophage cells treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ppap2a
25OHC/Ctl - treatment with 25-OHC / no treatment
25-OHC*/* - lipid depleted media containing compactin and treatment with 25-OHC / lipid depleted media containing compactin only
phosphatidic acid phosphatase 2a (Ppap2a), transcript variant 2, mRNA [NM_008903] 25OHC/Ctl (?) 1.03 1.05 1.00 .93 .95 .88 1.04
 25-OHC*/* (?) 1.00 1.00 1.12 .90 .89 .82 .73
 
 

Thioglycolate-elicited macrophage cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ppap2a
KLA  Compactin  Compactin+KLA
phosphatidic acid phosphatase 2a (Ppap2a), transcript variant 2, mRNA [NM_008903] KLA 1.05 .99 1.29 2.73 7.14 10.56 10.34
 Compactin 1.01 .94 1.07 .97 .84 .88 .61
 Compactin+KLA 1.07 .92 1.28 2.85 8.53 10.79 9.15

RAW 264.7 cells treated with Kdo2-Lipid A (KLA) and compactin

Gene Time course graph Description Treatment 30min 1h 2h 4h 8h 12h 24h
Ppap2a
KLA  Compactin  Compactin+KLA
phosphatidic acid phosphatase 2a (Ppap2a), transcript variant 2, mRNA [NM_008903] KLA 1.02 1.10 1.18 1.33 1.46 1.43 1.53
 Compactin 1.20 1.18 1.09 1.18 1.03 .99 1.32
 Compactin+KLA 1.18 1.16 1.17 1.19 1.31 1.49 1.58