Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: 7-oxo-cholesterol

Legend:graph_icon: View detailed data for replicatesgraph_icon: View time course graphs
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
Details Graph
Individual
Expts
Ave Biol. Reps
LM_ID Name 25-OHC*
*
25-OHC
Ctrl
0 hrs
25-OHC*
*
25-OHC
Ctrl
30 min
25-OHC*
*
25-OHC
Ctrl
1 hr
25-OHC*
*
25-OHC
Ctrl
2 hrs
25-OHC*
*
25-OHC
Ctrl
4 hrs
25-OHC*
*
25-OHC
Ctrl
8 hrs
25-OHC*
*
25-OHC
Ctrl
12 hrs
25-OHC*
*
25-OHC
Ctrl
24 hrs
Units
. . . .
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)
LMST01010049 7-oxo-cholesterol -
39.9
-
80.4
46.4
50.2
78.4
79.2
44.5
33.9
80.5
75
40.3
48.5
78.4
81.9
38.5
47
82.7
80.2
36
41.2
84.2
84.8
28.3
42.2
89.2
91.4
27.9
33.2
79.4
86.2
pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)
LMST01010049 7-oxo-cholesterol -
52.7
-
87.6
63.5
58.9
99.3
48.4
58.9
40.3
86.3
72
41.4
38.6
92.2
92.7
35.6
58.6
68.6
102
39
43.1
95.9
124
33.1
36.3
114
99
33.1
30.6
75.2
96.2
pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)
LMST01010049 7-oxo-cholesterol -
63.8
-
140
83.5
92.5
186
93.3
83.9
101
160
152
57.9
70.1
248
150
53.7
62.2
173
190
71.7
84.7
173
299
77
90.5
272
224
74.3
64.8
199
257
pmol/sample