Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: 7alpha-hydroxy-cholesterol

Legend:graph_icon: View detailed data for replicatesgraph_icon: View time course graphs
Ctrl:Untreated BMDM cells (control)
25-OHC: Cells treated with 25-OH-cholesterol at time 0
*: BMDM cells in lipid-depleted media containing compactin
25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0
Details Graph
Individual
Expts
Ave Biol. Reps
LM_ID Name 25-OHC*
*
25-OHC
Ctrl
0 hrs
25-OHC*
*
25-OHC
Ctrl
30 min
25-OHC*
*
25-OHC
Ctrl
1 hr
25-OHC*
*
25-OHC
Ctrl
2 hrs
25-OHC*
*
25-OHC
Ctrl
4 hrs
25-OHC*
*
25-OHC
Ctrl
8 hrs
25-OHC*
*
25-OHC
Ctrl
12 hrs
25-OHC*
*
25-OHC
Ctrl
24 hrs
Units
. . . .
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)
LMST01010013 7alpha-hydroxy-cholesterol -
9.2
-
6.65
7.91
20.6
8.54
9.94
3.56
34.3
10.6
11.1
28.6
7.11
11.5
4.04
27.6
19.5
15.7
6.16
15.2
11.2
8.7
4.84
20.8
9.79
9.36
12.2
25.6
23.4
31.6
44.2
pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)
LMST01010013 7alpha-hydroxy-cholesterol -
10.1
-
13.4
12.1
9.98
17.4
7.14
12.6
5.8
15
14.4
8.78
6.66
17.1
17.8
10.4
9.8
15
13.5
10.7
8.59
22.8
18.2
8.89
5.64
20.6
11
11.1
6.33
18
13.5
pmol/sample
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
 
Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp
(BCD100322)
LMST01010013 7alpha-hydroxy-cholesterol -
13.4
-
26.3
18.5
19.4
35.6
15.7
18.2
17
34.3
29.6
11.6
13.7
41.1
26.8
11.3
10.8
34
26.5
20.9
20.2
40.3
47.1
24.4
18.3
96
41.4
28.2
21.2
68.8
51.9
pmol/sample