Heatmap of Kdo timecourse data for lipid category ST (Ratio Kdo/ctrl values)

Gene symbols are linked to timecourse plots and probe annotations.

Lipids

Genes

symbol genename 30 1 1.5 2 4 6 8 12 18 24
Ch25h cholesterol 25-hydroxylase 1.12 1.00 1.66 3.17 4.08 1.88 1.73 1.31 1.18 1.18
Cyp51 cytochrome P450, family 51 1.24 1.82 1.81 1.75 1.09 0.87 1.06 1.08 0.58 0.41
Dhcr24 24-dehydrocholesterol reductase 1.05 1.09 1.10 0.95 0.57 0.55 0.52 0.61 0.47 0.30
Dhcr7 7-dehydrocholesterol reductase 1.08 1.01 0.91 0.70 0.41 0.55 0.53 0.70 0.60 0.56
Ebp phenylalkylamine Ca2+ antagonist (emopamil) binding protein 0.88 0.89 0.89 0.83 0.68 0.68 0.63 0.63 0.63 0.63
Fdft1 farnesyl diphosphate farnesyl transferase 1 1.09 1.14 1.16 1.16 1.05 0.92 1.03 1.05 0.91 0.79
Fdps farnesyl diphosphate synthetase 1.12 0.87 0.83 0.81 0.74 0.70 0.72 0.70 0.55 0.44
Ggps1 geranylgeranyl diphosphate synthase 1 0.90 0.94 0.99 1.02 1.32 1.67 1.58 1.61 1.48 1.58
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 1.55 1.94 2.04 1.87 1.76 1.72 1.65 1.69 1.40 1.05
Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 0.79 0.97 1.00 0.90 1.07 1.15 1.08 0.92 0.88 0.90
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 1.55 1.68 1.75 1.77 1.64 1.27 1.33 1.19 0.82 0.67
Idi1 isopentenyl-diphosphate delta isomerase 1.46 1.72 1.85 1.77 1.60 1.11 1.10 0.90 0.48 0.34
Lss lanosterol synthase 1.05 1.11 1.07 1.00 0.97 0.91 0.94 1.05 0.83 0.62
Mvd mevalonate (diphospho) decarboxylase 1.04 0.96 1.09 0.92 0.75 0.67 0.67 0.69 0.62 0.51
Mvk mevalonate kinase 1.16 1.14 1.14 1.00 0.88 0.91 0.80 0.89 0.80 0.67
Nsdhl NAD(P) dependent steroid dehydrogenase-like 1.14 1.21 1.25 1.19 1.04 0.95 0.98 1.00 0.66 0.56
Pmvk phosphomevalonate kinase 1.16 1.31 1.22 1.19 1.02 0.99 0.89 0.94 0.76 0.54
Sc4mol sterol-C4-methyl oxidase-like 1.28 1.65 1.68 1.56 0.97 1.11 1.23 1.29 0.76 0.67
Sc5d sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) 1.33 1.13 1.10 1.03 0.89 0.87 0.83 0.80 0.83 0.70
Soat1 sterol O-acyltransferase 1 1.02 0.98 0.98 0.94 1.01 1.62 1.65 2.27 3.03 2.92
Soat2 sterol O-acyltransferase 2 1.00 1.02 1.12 1.04 1.07 2.11 2.01 3.09 4.13 3.85
Sqle squalene epoxidase 1.07 1.11 1.18 1.07 0.74 0.77 1.07 0.89 0.72 0.64
Tm7sf2 transmembrane 7 superfamily member 2 0.88 0.86 0.90 0.84 0.81 0.69 0.59 0.52 0.46 0.48