LMPD Database

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LMP004325

Record overview

LMPD IDLMP004325
Gene ID123096
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
Gene SymbolSLC25A29
SynonymsC14orf69; CACL; ORNT3
Alternate namesmitochondrial basic amino acids transporter; solute carrier family 25, member 29; mitochondrial ornithine transporter 3; carnitine-acylcarnitine translocase like; carnitine/acylcarnitine translocase-like; mitochondrial carnitine/acylcarnitine carrier protein CACL
Chromosome14
Map Location14q32.2
SummaryThis gene encodes a nuclear-encoded mitochondrial protein that is a member of the large family of solute carrier family 25 (SLC25) mitochondrial transporters. The members of this superfamily are involved in numerous metabolic pathways and cell functions. This gene product was previously reported to be a mitochondrial carnitine-acylcarnitine-like (CACL) translocase (PMID:128829710) or an ornithine transporter (designated ORNT3, PMID:19287344), however, a recent study characterized the main role of this protein as a mitochondrial transporter of basic amino acids, with a preference for arginine and lysine (PMID:24652292). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
OrthologsView orthologs and multiple alignments for SLC25A29

Proteins

mitochondrial basic amino acids transporter isoform 1
Refseq ID:NP_001034444
Protein GI:86198310
UniProt ID:Q8N8R3
mRNA ID:NM_001039355
Length:303
RefSeq Status:REVIEWED
MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGA
AAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSG
IVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQP
SSL
 
mitochondrial basic amino acids transporter isoform 2
Refseq ID:NP_689546
Protein GI:22748727
UniProt ID:Q8N8R3
mRNA ID:NM_152333
Length:237
RefSeq Status:REVIEWED
MGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFG
VYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATF
ATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQPSSL
 
mitochondrial basic amino acids transporter isoform 2
Refseq ID:NP_001278743
Protein GI:625180323
UniProt ID:Q8N8R3
mRNA ID:NM_001291814
Length:237
RefSeq Status:REVIEWED
Protein sequence is identical to GI:22748727 (mRNA isoform)
 
mitochondrial basic amino acids transporter isoform 2
Refseq ID:NP_001278742
Protein GI:625180321
UniProt ID:Q8N8R3
mRNA ID:NM_001291813
Length:237
RefSeq Status:REVIEWED
Protein sequence is identical to GI:22748727 (mRNA isoform)