LMPD Database

LMP006701

Gene Information

Entrez Gene ID	57580
Gene Name	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Gene Symbol	PREX1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:HPA	C	cytoplasm
GO:0005829	IDA:UniProtKB	C	cytosol
GO:0043198	IEA:Ensembl	C	dendritic shaft
GO:0030426	IEA:Ensembl	C	growth cone
GO:0043231	IDA:HPA	C	intracellular membrane-bounded organelle
GO:0048471	IEA:Ensembl	C	perinuclear region of cytoplasm
GO:0005886	TAS:UniProtKB	C	plasma membrane
GO:0019899	TAS:UniProtKB	F	enzyme binding
GO:0005543	IDA:UniProtKB	F	phospholipid binding
GO:0005100	TAS:UniProtKB	F	Rho GTPase activator activity
GO:0005089	TAS:UniProtKB	F	Rho guanyl-nucleotide exchange factor activity
GO:0030041	TAS:UniProtKB	P	actin filament polymerization
GO:0007186	IEA:Ensembl	P	G-protein coupled receptor signaling pathway
GO:0035556	IEA:InterPro	P	intracellular signal transduction
GO:0042119	TAS:UniProtKB	P	neutrophil activation
GO:0030593	IEA:Ensembl	P	neutrophil chemotaxis
GO:0032855	IEA:Ensembl	P	positive regulation of Rac GTPase activity
GO:1900026	IEA:Ensembl	P	positive regulation of substrate adhesion-dependent cell spreading
GO:0030833	IEA:Ensembl	P	regulation of actin filament polymerization
GO:0050773	IEA:Ensembl	P	regulation of dendrite development
GO:0006801	TAS:UniProtKB	P	superoxide metabolic process
GO:0030217	IEA:Ensembl	P	T cell differentiation

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04062	Chemokine signaling pathway
ko04062	Chemokine signaling pathway