LMPD Database

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LMP006824

UniProt Annotations

Entry Information
Gene NameSwf1p
Protein EntrySWF1_YEAST
UniProt IDQ04629
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
DomainThe DHHC domain is required for palmitoyltransferase activity.
FunctionPalmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs SNC1, SNC2, SYN8 and TLG1, at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins
FunctionPalmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs SNC1, SNC2, SYN8 and TLG1, at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins. {ECO:0000269|PubMed:15973437}.
SimilarityBelongs to the DHHC palmitoyltransferase family. SWF1 subfamily
SimilarityBelongs to the DHHC palmitoyltransferase family. SWF1 subfamily. {ECO:0000305}.
SimilarityContains 1 DHHC-type zinc finger
SimilarityContains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:15973437}; Multi-pass membrane protein {ECO:0000269|PubMed:15973437}.
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .