LMPD Database

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LMP006892

UniProt Annotations

Entry Information
Gene Namedelta(24(24(1)))-sterol reductase
Protein EntryERG4_YEAST
UniProt IDP25340
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityErgosterol + NADP(+) = ergosta- 5,7,22,24(24(1))-tetraen-3-beta-ol + NADPH.
CautionWas originally thought to be a transport protein
CautionWas originally thought to be a transport protein. {ECO:0000305|PubMed:1882555}.
MiscellaneousPresent with 1640 molecules/cell in log phase SD medium
MiscellaneousPresent with 1640 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwaySteroid metabolism; ergosterol biosynthesis; ergosterol from zymosterol: step 5/5.
SimilarityBelongs to the ERG4/ERG24 family
SimilarityBelongs to the ERG4/ERG24 family. {ECO:0000305}.
Subcellular LocationMembrane; Multi-pass membrane protein.