LMPD Database

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LMP007023

UniProt Annotations

Entry Information
Gene NameCam1p
Protein EntryEF1G1_YEAST
UniProt IDP29547
SpeciesYeast (S288c)
Comments
Comment typeDescription
DomainThs GST-like domain mediates the interaction to eEFB1 and may be responsible for dimerization of the eEF1 complex.
FunctionSubunit of the eukaryotic elongation factor 1 complex (eEF1). Probably plays a role in anchoring the complex to other cellular components. May be involved in transcriptional regulation of MXR1. {ECO:0000269|PubMed:12824466}.
MiscellaneousPresent with 60865 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
MiscellaneousThere are 2 isoforms for eEF1Bgamma in yeast.
PathwayProtein biosynthesis; polypeptide chain elongation.
SimilarityContains 1 EF-1-gamma C-terminal domain. {ECO:0000255|PROSITE-ProRule:PRU00519}.
SimilarityContains 1 GST C-terminal domain. {ECO:0000305}.
SimilarityContains 1 GST N-terminal domain. {ECO:0000305}.
Subcellular LocationCytoplasm. Nucleus.
SubunitThe eukaryotic elongation factor 1 complex (eEF1) is probably a heterohexamer. Two trimeric complexes, each composed of eEF1A (TEF1 or TEF2), eEF1Balpha (EFB1) and eEF1Bgamma (CAM1 or TEF4), are probably dimerized via the eF1Bgamma subunits. The eEF1B subcomplex with the GEF activity is formed of eEF1Balpha and eEF1Bgamma. CAM1 interacts with EFB1. Component of a complex bound to MXR1 promoter region. {ECO:0000269|PubMed:12972429}.