LMPD Database

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LMP007033

UniProt Annotations

Entry Information
Gene NameYeh1p
Protein EntryYEH1_YEAST
UniProt IDQ07804
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityA steryl ester + H(2)O = a sterol + a fatty acid.
FunctionMediates the hydrolysis of steryl esters, thereby playing a central role in lipid metabolism. Under heme-deficient conditions, it constitutes the major steryl ester hydrolase, suggesting that it plays a central role in mobilization of steryl esters under anaerobic conditions. {ECO:0000269|PubMed:15713625, ECO:0000269|PubMed:16835446}.
InductionUnder heme-deficiency conditions. Heme-deficient induction requires ROX3. {ECO:0000269|PubMed:16835446}.
MiscellaneousPresent with 7770 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PtmNot N-glycosylated.
SimilarityBelongs to the AB hydrolase superfamily. {ECO:0000305}.
Subcellular LocationLipid droplet. Membrane; Peripheral membrane protein.