LMPD Database

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LMP007166

UniProt Annotations

Entry Information
Gene Namephytoceramidase
Protein EntryYPC1_YEAST
UniProt IDP38298
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionHydrolyzes phytoceramide and also dihydroceramide into phytosphingosine or dihydrosphingosine. Prefers phytoceramide. Has also reverse hydrolysis activity, catalyzing synthesis of phytoceramide and dihydroceramide from palmitic acid and phytosphingosine or dihydrosphingosine. Is not responsible for the breakdown of unsaturated ceramide.
InteractionP25376:AGP1; NbExp=1; IntAct=EBI-2103141, EBI-2357; P08456:CHO1; NbExp=1; IntAct=EBI-2103141, EBI-14055; P53337:ERV29; NbExp=1; IntAct=EBI-2103141, EBI-23662; P41543:OST1; NbExp=1; IntAct=EBI-2103141, EBI-12651; P40975:PMP2; NbExp=1; IntAct=EBI-2103141, EBI-2043041; Q04947:RTN1; NbExp=1; IntAct=EBI-2103141, EBI-38020; P32368:SAC1; NbExp=1; IntAct=EBI-2103141, EBI-16210; P39986:SPF1; NbExp=1; IntAct=EBI-2103141, EBI-3128; P23255:TAF2; NbExp=1; IntAct=EBI-2103141, EBI-18862; P38800:YHR080C; NbExp=1; IntAct=EBI-2103141, EBI-24597;
SimilarityBelongs to the alkaline ceramidase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.