LMPD Database

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LMP007383

UniProt Annotations

Entry Information
Gene NameTsc3p
Protein EntryTSC3_YEAST
UniProt IDQ3E790
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionStimulates the activity of serine palmitoyltransferase (SPT).
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:10713067, ECO:0000269|PubMed:14562095}; Single-pass membrane protein {ECO:0000269|PubMed:10713067, ECO:0000269|PubMed:14562095}.
Subcellular LocationEndoplasmic reticulum membrane ; Single-pass membrane protein {ECO:0000269|PubMed:10713067, ECO:0000269|PubMed:14562095}.
SubunitInteracts with the serine palmitoyltransferase complex LCB1-LCB2. Component of the SPOTS complex, at least composed of LCB1/2 (LCB1 and/or LCB2), ORM1/2 (ORM1 and/or ORM2), SAC1 and TSC3
SubunitInteracts with the serine palmitoyltransferase complex LCB1-LCB2. Component of the SPOTS complex, at least composed of LCB1/2 (LCB1 and/or LCB2), ORM1/2 (ORM1 and/or ORM2), SAC1 and TSC3. {ECO:0000269|PubMed:10713067, ECO:0000269|PubMed:20182505}.