LMPD Database

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LMP007448

UniProt Annotations

Entry Information
Gene NameCax4p
Protein EntryCAX4_YEAST
UniProt IDP53223
SpeciesYeast (S288c)
Comments
Comment typeDescription
Biophysicochemical PropertiespH dependence: Optimum pH is 6-7.;
Biophysicochemical PropertiespH dependence: Optimum pH is 6-7.;
Catalytic ActivityDolichyl diphosphate + H(2)O = dolichyl phosphate + phosphate.
FunctionNon-essential protein which is required for efficient N- glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate
FunctionNon-essential protein which is required for efficient N- glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate. {ECO:0000269|PubMed:10024662, ECO:0000269|PubMed:11504728}.
InteractionSelf; NbExp=1; IntAct=EBI-23136, EBI-23136; P25376:AGP1; NbExp=1; IntAct=EBI-23136, EBI-2357; P38242:ALG14; NbExp=1; IntAct=EBI-23136, EBI-21477; P08456:CHO1; NbExp=1; IntAct=EBI-23136, EBI-14055; P40975:PMP2; NbExp=1; IntAct=EBI-23136, EBI-2043041; P39986:SPF1; NbExp=1; IntAct=EBI-23136, EBI-3128;
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the dolichyldiphosphatase family
SimilarityBelongs to the dolichyldiphosphatase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:11504728}; Multi-pass membrane protein {ECO:0000269|PubMed:11504728}.
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .