LMPD Database

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LMP007497

UniProt Annotations

Entry Information
Gene Nametranscription factor IIF subunit TFG1
Protein EntryT2FA_YEAST
UniProt IDP41895
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionTFIIF is a general transcription initiation factor that binds to RNA polymerase II. Its functions include the recruitment of RNA polymerase II to the promoter bound DNA-TBP-TFIIB complex, decreasing the affinity of RNA polymerase II for non-specific DNA, allowing for the subsequent recruitment of TFIIE and TFIIH, and facilitating RNA polymerase II elongation. {ECO:0000269|PubMed:1331085}.
MiscellaneousPresent with 1920 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PtmPhosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases. {ECO:0000250}.
SimilarityBelongs to the TFIIF alpha subunit family. {ECO:0000305}.
Subcellular LocationNucleus.
SubunitTFIIF is composed of three different subunits: TFG1/RAP74, TFG2/RAP30 and TAF14.